In order to improve the quality of higher education and teaching, higher education courses requires the perpetual reform, which can make the higher education courses follow the frontier development of discipline and keep on the times. Based on using appropriate teaching material, stimulating students’ interest, training the quality of teachers, improving teaching methods, teaching methods and other aspects, this paper proposes some suggestions for experimental design course to improve teaching means and methods, which can enable students to improve the learning interest, deepen the understanding of theoretical knowledge, and through a variety of ways to eventually reach the goal of mastering the course, laid a solid foundation for the future study and work.