Program for testing biological interventions to promote healthy aging

[1]  J. Morrow,et al.  Measurement of F(2)-isoprostanes as an index of oxidative stress in vivo. , 2000, Free radical biology & medicine.

[2]  Pier Paolo Pandolfi,et al.  The p66shc adaptor protein controls oxidative stress response and life span in mammals , 1999, Nature.

[3]  C. K. Lee,et al.  Gene expression profile of aging and its retardation by caloric restriction. , 1999, Science.

[4]  R. Miller,et al.  Kleemeier award lecture: are there genes for aging? , 1999, The journals of gerontology. Series A, Biological sciences and medical sciences.

[5]  J. Tower,et al.  FLP Recombinase-Mediated Induction of Cu/Zn-Superoxide Dismutase Transgene Expression Can Extend the Life Span of Adult Drosophila melanogaster Flies , 1999, Molecular and Cellular Biology.

[6]  B. Ames,et al.  Acetyl-L-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[7]  A. Elia,et al.  Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons , 1998, Nature Genetics.

[8]  Koutarou D. Kimura,et al.  daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. , 1997, Science.

[9]  Andrzej Bartke,et al.  Dwarf mice and the ageing process , 1996, Nature.

[10]  G. Ruvkun,et al.  A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans , 1996, Nature.

[11]  R. Bucala,et al.  Prevention of cardiovascular and renal pathology of aging by the advanced glycation inhibitor aminoguanidine. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[12]  L. Packer,et al.  The Spin-Trap N-tert-α-Phenylbutylnitrone Prolongs the Life Span of the Senescence-Accelerated Mouse , 1995 .

[13]  D. Ingram,et al.  Diet restriction in rhesus monkeys lowers fasting and glucose-stimulated glucoregulatory end points. , 1995, The American journal of physiology.

[14]  R. Bergman,et al.  Dietary restriction increases insulin sensitivity and lowers blood glucose in rhesus monkeys. , 1994, The American journal of physiology.

[15]  W. Pierpaoli,et al.  Pineal control of aging: effect of melatonin and pineal grafting on aging mice. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[16]  R. Floyd,et al.  Reversal of age-related increase in brain protein oxidation, decrease in enzyme activity, and loss in temporal and spatial memory by chronic administration of the spin-trapping compound N-tert-butyl-alpha-phenylnitrone. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[17]  Richard Weindruch,et al.  The Retardation of Aging and Disease by Dietary Restriction , 1988 .

[18]  W. Cefalu,et al.  A study of caloric restriction and cardiovascular aging in cynomolgus monkeys (Macaca fascicularis): a potential model for aging research. , 1997, The journals of gerontology. Series A, Biological sciences and medical sciences.