Meta-analysis of 20 genome-wide linkage studies evidenced new regions linked to asthma and atopy

[1]  S. Holgate,et al.  Genetics of allergic disease. , 2010, The Journal of allergy and clinical immunology.

[2]  A. Singleton,et al.  Genomewide association studies and human disease. , 2009, The New England journal of medicine.

[3]  N. Camp,et al.  Significant evidence for linkage to chromosome 5q13 in a genome-wide scan for asthma in an extended pedigree resource , 2009, European Journal of Human Genetics.

[4]  D. Postma,et al.  Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction , 2009, Nature Genetics.

[5]  J. Bousquet,et al.  Effect of 17q21 variants and smoking exposure in early-onset asthma. , 2008, The New England journal of medicine.

[6]  B. Maher.  Personal genomes: The case of the missing heritability , 2008, Nature.

[7]  Manuel A. R. Ferreira,et al.  Meta-analysis of genome-wide linkage studies of asthma and related traits , 2008, Respiratory research.

[8]  D. Vercelli,et al.  Discovering susceptibility genes for asthma and allergy , 2008, Nature Reviews Immunology.

[9]  S. Rich,et al.  5. Genetics of allergic disease. , 2008, The Journal of allergy and clinical immunology.

[10]  U. Wahn,et al.  Variants in a Novel Epidermal Collagen Gene (COL29A1) Are Associated with Atopic Dermatitis , 2007, PLoS biology.

[11]  M. Lathrop,et al.  Scores of asthma and asthma severity reveal new regions of linkage in EGEA study families , 2007, European Respiratory Journal.

[12]  Gonçalo R. Abecasis,et al.  Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma , 2007, Nature.

[13]  M. Pericak-Vance,et al.  A genome-wide search for linkage to asthma phenotypes in the genetics of asthma international network families: evidence for a major susceptibility locus on chromosome 2p , 2007, European Journal of Human Genetics.

[14]  D. Schlessinger,et al.  IRAK-M is involved in the pathogenesis of early-onset persistent asthma. , 2007, American journal of human genetics.

[15]  S. Fisher,et al.  Meta-analysis of genome-wide linkage studies for multiple sclerosis, using an extended GSMA method , 2007, European Journal of Human Genetics.

[16]  K. Barnes,et al.  Quantitative linkage genome scan for atopy in a large collection of Caucasian families , 2007, Human Genetics.

[17]  N. Freimer,et al.  Sex-specific linkage to total serum immunoglobulin E in families of children with asthma in Costa Rica. , 2007, Human molecular genetics.

[18]  N. Freimer,et al.  Significant linkage to airway responsiveness on chromosome 12q24 in families of children with asthma in Costa Rica , 2006, Human Genetics.

[19]  S. Wenzel.  Asthma: defining of the persistent adult phenotypes , 2006, The Lancet.

[20]  M. Pericak-Vance,et al.  A genome-wide search for linkage to asthma phenotypes in the genetics of asthma international network families: evidence for a major susceptibility locus on chromosome 2p , 2006, European Journal of Human Genetics.

[21]  Larry Wasserman,et al.  Using linkage genome scans to improve power of association in genome scans. , 2006, American journal of human genetics.

[22]  Douglas F. Levinson,et al.  GSMA: software implementation of the genome search meta-analysis method , 2005, Bioinform..

[23]  Nicholas G Martin,et al.  Robust estimation of experimentwise P values applied to a genome scan of multiple asthma traits identifies a new region of significant linkage on chromosome 20q13. , 2005, American journal of human genetics.

[24]  John P. A. Ioannidis,et al.  HEGESMA: genome search meta-analysis and heterogeneity testing , 2005, Bioinform..

[25]  D. Postma,et al.  Genomewide screen for pulmonary function in 200 families ascertained for asthma. , 2005, American journal of respiratory and critical care medicine.

[26]  M. Shimizu,et al.  Positional identification of an asthma susceptibility gene on human chromosome 5q33. , 2005, American journal of respiratory and critical care medicine.

[27]  D. Postma,et al.  Genome screen for asthma and bronchial hyperresponsiveness: interactions with passive smoke exposure. , 2005, The Journal of allergy and clinical immunology.

[28]  John P A Ioannidis,et al.  Heterogeneity testing in meta‐analysis of genome searches , 2005, Genetic epidemiology.

[29]  Daniel H. Schneider,et al.  Fine mapping and positional candidate studies identify HLA-G as an asthma susceptibility gene on chromosome 6p21. , 2005, American journal of human genetics.

[30]  K. Strauch,et al.  A genome‐wide screen on the genetics of atopy in a multiethnic European population reveals a major atopy locus on chromosome 3q21.3 , 2005, Allergy.

[31]  M. Wjst,et al.  Phenotypic and genetic heterogeneity in a genome-wide linkage study of asthma families , 2005, BMC pulmonary medicine.

[32]  J. Bousquet,et al.  Clustering patterns of LOD scores for asthma-related phenotypes revealed by a genome-wide screen in 295 French EGEA families. , 2004, Human molecular genetics.

[33]  David M. Evans,et al.  Major quantitative trait locus for eosinophil count is located on chromosome 2q. , 2004, The Journal of allergy and clinical immunology.

[34]  A. Togias,et al.  Genome scan for loci linked to mite sensitivity: the Collaborative Study on the Genetics of Asthma (CSGA) , 2004, Genes and Immunity.

[35]  Ricardo Segurado,et al.  Genome scan meta-analysis of schizophrenia and bipolar disorder, part I: Methods and power analysis. , 2003, American journal of human genetics.

[36]  M. Leppert,et al.  A genome-wide scan of pulmonary function measures in the National Heart, Lung, and Blood Institute Family Heart Study. , 2003, American journal of respiratory and critical care medicine.

[37]  T. Beaty,et al.  Evidence for gene-environment interactions in a linkage study of asthma and smoking exposure. , 2003, The Journal of allergy and clinical immunology.

[38]  J. Gulcher,et al.  A major susceptibility gene for asthma maps to chromosome 14q24. , 2002, American journal of human genetics.

[39]  R. Dahl,et al.  Asthma and atopy – a total genome scan for susceptibility genes , 2002, Allergy.

[40]  Steuart Rorke,et al.  Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness , 2002, Nature.

[41]  D. Postma,et al.  Genome-wide search for atopy susceptibility genes in Dutch families with asthma. , 2002, The Journal of allergy and clinical immunology.

[42]  S. Lewitzky,et al.  A genomewide search for quantitative-trait loci underlying asthma. , 2001, American journal of human genetics.

[43]  T. Beaty,et al.  Genomewide screen and identification of gene-gene interactions for asthma-susceptibility loci in three U.S. populations: collaborative study on the genetics of asthma. , 2001, American journal of human genetics.

[44]  M. Daly,et al.  A susceptibility locus for asthma-related traits on chromosome 7 revealed by genome-wide scan in a founder population , 2001, Nature Genetics.

[45]  T. Beaty,et al.  Genome‐wide linkage analyses of total serum IgE using variance components analysis in asthmatic families , 2001, Genetic epidemiology.

[46]  D. Postma,et al.  Major genes regulating total serum immunoglobulin E levels in families with asthma. , 2000, American journal of human genetics.

[47]  T. Arinami,et al.  Significant evidence for linkage of mite-sensitive childhood asthma to chromosome 5q31-q33 near the interleukin 12 B locus by a genome-wide search in Japanese families. , 2000, Genomics.

[48]  M. Wjst.  Specific IgE--one gene fits all? German Asthma Genetics Group. , 1999, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[49]  J. Lanchbury,et al.  Meta‐analysis of genome searches , 1999, Annals of human genetics.

[50]  M. Wjst,et al.  A Genome-wide Search for Linkage to Asthma , 1999 .

[51]  E. Lander,et al.  Genome-Wide Search for Asthma Susceptibility Loci in a Founder Population , 1998 .

[52]  Farhad Imani,et al.  A genome-wide search for asthma susceptibility loci in ethnically diverse populations , 1997, Nature Genetics.

[53]  G. Lathrop,et al.  A genome-wide search for quantitative trait loci underlying asthma , 1996, Nature.

[54]  T. Beaty,et al.  A genome-wide search for allergic response (atopy) genes in three ethnic groups: Collaborative Study on the Genetics of Asthma , 2003, Human Genetics.

[55]  M. Wjst,et al.  A genome-wide search for linkage to asthma. German Asthma Genetics Group. , 1999, Genomics.

[56]  E. Lander,et al.  Genome-wide search for asthma susceptibility loci in a founder population. The Collaborative Study on the Genetics of Asthma. , 1998, Human molecular genetics.

[57]  A genome-wide search for asthma susceptibility loci in ethnically diverse populations. The Collaborative Study on the Genetics of Asthma (CSGA). , 1997, Nature genetics.