Expression pattern and phosphorylation status of Smad2/3 in different subtypes of human first trimester trophoblast.

[1]  C. Fiala,et al.  Notch1 controls development of the extravillous trophoblast lineage in the human placenta , 2016, Proceedings of the National Academy of Sciences.

[2]  C. Fiala,et al.  Wingless ligand 5a is a critical regulator of placental growth and survival , 2016, Scientific Reports.

[3]  D. D. de Kretser,et al.  Activins in reproductive biology and beyond. , 2016, Human reproduction update.

[4]  M. Post,et al.  Aberrant TGFβ Signaling Contributes to Altered Trophoblast Differentiation in Preeclampsia. , 2016, Endocrinology.

[5]  C. Fiala,et al.  Neuregulin-1-mediated ErbB2–ErbB3 signalling protects human trophoblasts against apoptosis to preserve differentiation , 2015, Journal of Cell Science.

[6]  P. Leung,et al.  Activin A Increases Human Trophoblast Invasion by Inducing SNAIL-Mediated MMP2 Up-Regulation Through ALK4. , 2015, The Journal of clinical endocrinology and metabolism.

[7]  B. Stranger,et al.  Human HLA-G+ extravillous trophoblasts: Immune-activating cells that interact with decidual leukocytes , 2015, Proceedings of the National Academy of Sciences.

[8]  Liling Li,et al.  TGF-β induces fascin expression in gastric cancer via phosphorylation of smad3 linker area. , 2015, American journal of cancer research.

[9]  L. Ermini,et al.  Aberrant TGFβ Signalling Contributes to Dysregulation of Sphingolipid Metabolism in Intrauterine Growth Restriction. , 2015, The Journal of clinical endocrinology and metabolism.

[10]  H. Huber,et al.  Axl activates autocrine transforming growth factor‐β signaling in hepatocellular carcinoma , 2015, Hepatology.

[11]  Hongyan Yuan,et al.  Mucin1 mediates autocrine transforming growth factor beta signaling through activating the c-Jun N-terminal kinase/activator protein 1 pathway in human hepatocellular carcinoma cells. , 2015, The international journal of biochemistry & cell biology.

[12]  P. Leung,et al.  Activin A, B, and AB increase human trophoblast cell invasion by up-regulating N-cadherin. , 2014, The Journal of clinical endocrinology and metabolism.

[13]  J. James,et al.  The relationship between TGFβ, low oxygen and the outgrowth of extravillous trophoblasts from anchoring villi during the first trimester of pregnancy. , 2014, Cytokine.

[14]  V. Fock,et al.  Extravillous Trophoblast-Associated ADAM12 Exerts Pro-Invasive Properties, Including Induction of Integrin Beta 1-Mediated Cellular Spreading1 , 2014, Biology of reproduction.

[15]  A. Moffett,et al.  Uterine NK cells: active regulators at the maternal-fetal interface. , 2014, The Journal of clinical investigation.

[16]  C. Fiala,et al.  Wnt-dependent T-cell factor-4 controls human etravillous trophoblast motility. , 2014, Endocrinology.

[17]  P. Leung,et al.  Transforming Growth Factor-β1 Inhibits Trophoblast Cell Invasion by Inducing Snail-mediated Down-regulation of Vascular Endothelial-cadherin Protein* , 2013, The Journal of Biological Chemistry.

[18]  Wenhua Zheng,et al.  Transforming growth factor-β signalling: role and consequences of Smad linker region phosphorylation. , 2013, Cellular signalling.

[19]  K. Matsuzaki Smad phospho-isoforms direct context-dependent TGF-β signaling. , 2013, Cytokine & growth factor reviews.

[20]  S. Fisher,et al.  Reversal of gene dysregulation in cultured cytotrophoblasts reveals possible causes of preeclampsia. , 2013, The Journal of clinical investigation.

[21]  G. Sapkota,et al.  Phosphatases in SMAD regulation , 2012, FEBS letters.

[22]  C. Fiala,et al.  Evaluation of human first trimester decidual and telomerase-transformed endometrial stromal cells as model systems of in vitro decidualization , 2011, Reproductive biology and endocrinology : RB&E.

[23]  L. Harris,et al.  IFPA Gabor Than Award lecture: Transformation of the spiral arteries in human pregnancy: key events in the remodelling timeline. , 2011, Placenta.

[24]  M. Westwood,et al.  Transforming growth factor-{beta} (TGF{beta}) receptors I/II differentially regulate TGF{beta}1 and IGF-binding protein-3 mitogenic effects in the human placenta. , 2010, Endocrinology.

[25]  R. Crystal,et al.  A SNAIL1–SMAD3/4 transcriptional repressor complex promotes TGF-β mediated epithelial–mesenchymal transition , 2009, Nature Cell Biology.

[26]  C. Sturgis,et al.  Transforming Growth Factor-β1, Transforming Growth Factor-β2, and Transforming Growth Factor-β3 Enhance Ovarian Cancer Metastatic Potential by Inducing a Smad3-Dependent Epithelial-to-Mesenchymal Transition , 2008, Molecular Cancer Research.

[27]  R. Pijnenborg,et al.  The uterine spiral arteries in human pregnancy: facts and controversies. , 2006, Placenta.

[28]  Rebecca L. Jones,et al.  TGF-β superfamily expression and actions in the endometrium and placenta , 2006 .

[29]  J. Massagué,et al.  Smad transcription factors. , 2005, Genes & development.

[30]  S. Robson,et al.  Inhibition of Trophoblast Cell Invasion by TGFB1, 2, and 3 Is Associated with a Decrease in Active Proteases1 , 2005, Biology of reproduction.

[31]  E. Jauniaux,et al.  Endometrial glands as a source of nutrients, growth factors and cytokines during the first trimester of human pregnancy: A morphological and immunohistochemical study , 2004, Reproductive biology and endocrinology : RB&E.

[32]  A. Moffett-King Natural killer cells and pregnancy , 2002, Nature Reviews Immunology.

[33]  M. Vidaud,et al.  Characterization of Human Villous and Extravillous Trophoblasts Isolated from First Trimester Placenta , 2001, Laboratory Investigation.

[34]  M. Gassmann,et al.  Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFβ3 , 2000 .

[35]  J. Wrana Regulation of Smad Activity , 2000, Cell.

[36]  K. Lim,et al.  Human cytotrophoblast differentiation/invasion is abnormal in pre-eclampsia. , 1997, The American journal of pathology.

[37]  J. Sugawara,et al.  Hepatocyte Growth Factor Stimulates Proliferation, Migration, and Lumen Formation of Human Endometrial Epithelial Cells In Vitro , 1997 .

[38]  C. Damsky,et al.  Preeclampsia is associated with failure of human cytotrophoblasts to mimic a vascular adhesion phenotype. One cause of defective endovascular invasion in this syndrome? , 1997, The Journal of clinical investigation.

[39]  K. Kaji [Platelet-derived growth factor (PDGF)]. , 1995, Nihon rinsho. Japanese journal of clinical medicine.

[40]  W. Stetler-Stevenson,et al.  Resistance of malignant trophoblast cells to both the anti-proliferative and anti-invasive effects of transforming growth factor-beta. , 1994, Experimental cell research.

[41]  K. McCrae,et al.  Localization of transforming growth factor-beta at the human fetal-maternal interface: role in trophoblast growth and differentiation. , 1992, Biology of reproduction.

[42]  N. Chegini,et al.  Platelet-derived growth factor (PDGF), epidermal growth factor (EGF), and EGF and PDGF beta-receptors in human endometrial tissue: localization and in vitro action. , 1992, Endocrinology.

[43]  R. Pijnenborg,et al.  Placental bed spiral arteries in the hypertensive disorders of pregnancy , 1991, British journal of obstetrics and gynaecology.

[44]  J. Hustin,et al.  Histological study of the materno-embryonic interface in spontaneous abortion. , 1990, Placenta.

[45]  C. Labarrere,et al.  Inadequate maternal vascular response to placentation in pregnancies complicated by preeclampsia and by small‐for‐gestational‐age infants , 1987, British journal of obstetrics and gynaecology.

[46]  T. Khong,et al.  Inadequate maternal vascular response to placentation in pregnancies complicated by pre‐eclampsia and by small‐for‐gestational age infants , 1986 .

[47]  J. Bland,et al.  Uteroplacental arterial changes related to interstitial trophoblast migration in early human pregnancy. , 1983, Placenta.

[48]  C. Fiala,et al.  Notch signaling plays a critical role in motility and differentiation of human first-trimester cytotrophoblasts. , 2014, Endocrinology.

[49]  D. Charnock-Jones,et al.  The influence of the intrauterine environment on human placental development. , 2010, The International journal of developmental biology.

[50]  Rebecca L. Jones,et al.  TGF-beta superfamily expression and actions in the endometrium and placenta. , 2006, Reproduction.

[51]  J. Massagué How cells read TGF-beta signals. , 2000, Nature reviews. Molecular cell biology.

[52]  M. Gassmann,et al.  Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFbeta(3) , 2000, The Journal of clinical investigation.

[53]  J. Massagué TGF-beta signal transduction. , 1998, Annual review of biochemistry.

[54]  J. Cross,et al.  Activin Is a Local Regulator of Human Cytotrophoblast Cell Differentiation * , 1997 .

[55]  Caroline,et al.  Distribution patterns of extracellular matrix components and adhesion receptors are intricately modulated during first trimester cytotrophoblast differentiation along the invasive pathway, in vivo. , 1992, The Journal of clinical investigation.

[56]  R. Pijnenborg,et al.  Trophoblastic invasion of human decidua from 8 to 18 weeks of pregnancy. , 1980, Placenta.