Definitive relationships among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the U.S. NTP.

[1]  J. French,et al.  Development and validation of a cellular transplant model for leukemia in Fischer rats: a short-term assay for potential anti-leukemic chemicals. , 1989, Leukemia research.

[2]  R. Cattley,et al.  Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (Wy-14,643) in rats. , 1988, Cancer research.

[3]  R. Tennant,et al.  Chemical structure, Salmonella mutagenicity and extent of carcinogenicity as indicators of genotoxic carcinogenesis among 222 chemicals tested in rodents by the U.S. NCI/NTP. , 1988, Mutation research.

[4]  M. D. Hogan,et al.  The impact of toxicity on carcinogenicity studies: implications for risk assessment. , 1988, Carcinogenesis.

[5]  J. Selkirk,et al.  An overview of prechronic and chronic toxicity/carcinogenicity experimental study designs and criteria used by the National Toxicology Program. , 1990, Environmental health perspectives.

[6]  C. F. Wilkinson,et al.  Thyroid follicular cell carcinogenesis. , 1989, Fundamental and applied toxicology : official journal of the Society of Toxicology.

[7]  D. Bleyl,et al.  IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. Overall Evaluations of Carcinogenicity: An Updating of IARC Monographs vol. 1 to 42. Supplement 7. 440 Seiten. International Agency for Research on Cancer, Lyon 1987. Preis: 65, – s.Fr , 1989 .

[8]  C. Westmoreland,et al.  Effects of azobenzene and aniline in the rodent bone marrow micronucleus test. , 1990, Carcinogenesis.

[9]  F. M. Johnson,et al.  Short-term tests are unable to distinguish between human carcinogens and noncarcinogens. , 1986, Cancer investigation.

[10]  B H Margolin,et al.  Prediction of chemical carcinogenicity in rodents from in vitro genetic toxicity assays. , 1987, Science.

[11]  R R Maronpot,et al.  Activated oncogenes in B6C3F1 mouse liver tumors: implications for risk assessment. , 1987, Science.

[12]  G. Williams,et al.  The decision-point approach for systematic carcinogen testing. , 1981, Food and cosmetics toxicology.

[13]  J. Ashby,et al.  Genetic activity of the human carcinogen sulphur mustard towards Salmonella and the mouse bone marrow. , 1991, Mutation research.

[14]  J. Ashby,et al.  Methyl vinyl sulphone: a new class of Michael-type genotoxin. , 1990, Mutation research.

[15]  I. Issemann,et al.  Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators , 1990, Nature.

[16]  R. Tennant,et al.  Classification according to chemical structure, mutagenicity to Salmonella and level of carcinogenicity of a further 39 chemicals tested for carcinogenicity by the U.S. National Toxicology Program. , 1991, Mutation research.

[17]  M. Shelby.  The genetic toxicity of human carcinogens and its implications. , 1988, Mutation research.

[18]  E Zeiger,et al.  Activity of human carcinogens in the Salmonella and rodent bone-marrow cytogenetics tests. , 1990, Mutation research.

[19]  J Ashby,et al.  The prospects for a simplified and internationally harmonized approach to the detection of possible human carcinogens and mutagens. , 1986, Mutagenesis.

[20]  T. Goldsworthy,et al.  Chlorinated hydrocarbon-induced peroxisomal enzyme activity in relation to species and organ carcinogenicity. , 1987, Toxicology and applied pharmacology.

[21]  D. Brusick,et al.  The Salmonella typhimurium/mammalian microsomal assay. A report of the U.S. Environmental Protection Agency Gene-Tox Program. , 1986, Mutation research.

[22]  J Ashby,et al.  Correlations between bioassay dose-level, mutagenicity to Salmonella, chemical structure and sites of carcinogenesis among 226 chemicals evaluated for carcinogenicity by the U.S. NTP. , 1990, Mutation research.

[23]  B. Ames,et al.  Too many rodent carcinogens: mitogenesis increases mutagenesis. , 1990, Science.

[24]  T. Goldsworthy,et al.  Potential role of alpha-2 mu-globulin, protein droplet accumulation, and cell replication in the renal carcinogenicity of rats exposed to trichloroethylene, perchloroethylene, and pentachloroethane. , 1988, Toxicology and applied pharmacology.