Immunization with genetically attenuated P52-deficient Plasmodium berghei sporozoites induces a long-lasting effector memory CD8+ T cell response in the liver

[1]  D. Doolan,et al.  Harnessing immune responses against Plasmodium for rational vaccine design. , 2011, Trends in parasitology.

[2]  N. Van Rooijen,et al.  Prolonged Antigen Presentation Is Required for Optimal CD8+ T Cell Responses against Malaria Liver Stage Parasites , 2010, PLoS pathogens.

[3]  Sumana Chakravarty,et al.  Development of a metabolically active, non-replicating sporozoite vaccine to prevent Plasmodium falciparum malaria , 2010, Human vaccines.

[4]  R. Ménard,et al.  Role of Plasmodium berghei cGMP-dependent Protein Kinase in Late Liver Stage Development* , 2009, The Journal of Biological Chemistry.

[5]  S. Kappe,et al.  Genetically Attenuated Parasite Vaccines Induce Contact-Dependent CD8+ T Cell Killing of Plasmodium yoelii Liver Stage-Infected Hepatocytes1 , 2009, The Journal of Immunology.

[6]  Lyric C. Bartholomay,et al.  Memory CD8 T cell responses exceeding a large but definable threshold provide long-term immunity to malaria , 2008, Proceedings of the National Academy of Sciences.

[7]  Daniel G. Anderson,et al.  Heme oxygenase-1 is an anti-inflammatory host factor that promotes murine plasmodium liver infection. , 2008, Cell host & microbe.

[8]  M. Mota,et al.  Genetically attenuated P36p-deficient Plasmodium berghei sporozoites confer long-lasting and partial cross-species protection. , 2007, International journal for parasitology.

[9]  S. Kappe,et al.  Genetically attenuated Plasmodium berghei liver stages induce sterile protracted protection that is mediated by major histocompatibility complex Class I-dependent interferon-gamma-producing CD8+ T cells. , 2007, The Journal of infectious diseases.

[10]  I. Coppens,et al.  Plasmodium yoelii Sporozoites with Simultaneous Deletion of P52 and P36 Are Completely Attenuated and Confer Sterile Immunity against Infection , 2007, Infection and Immunity.

[11]  D. Doolan,et al.  Immune response to pre-erythrocytic stages of malaria parasites. , 2006, Current molecular medicine.

[12]  Y. Chinzei,et al.  Two proteins with 6‐cys motifs are required for malarial parasites to commit to infection of the hepatocyte , 2005, Molecular microbiology.

[13]  M. Mota,et al.  Genetically attenuated, P36p-deficient malarial sporozoites induce protective immunity and apoptosis of infected liver cells. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[14]  S. Kappe,et al.  Plasmodium liver stage developmental arrest by depletion of a protein at the parasite-host interface. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[15]  S. Kappe,et al.  Genetically modified Plasmodium parasites as a protective experimental malaria vaccine , 2005, Nature.

[16]  Jackie Williams,et al.  Protracted Protection to Plasmodium berghei Malaria Is Linked to Functionally and Phenotypically Heterogeneous Liver Memory CD8+ T Cells1 , 2003, The Journal of Immunology.

[17]  U. Krzych,et al.  Memory phenotype CD8+ T cells persist in livers of mice protected against malaria by immunization with attenuated Plasmodium bergheisporozoites , 1999, European journal of immunology.

[18]  A. Azad,et al.  Maintenance of protective immunity against malaria by persistent hepatic parasites derived from irradiated sporozoites. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[19]  R. Gwadz,et al.  Simple centrifugation method for rapid separation of sporozoites from mosquitoes. , 1984, The Journal of parasitology.

[20]  U. Krzych,et al.  The dissection of CD8 T cells during liver-stage infection. , 2005, Current topics in microbiology and immunology.