A randomized sequential trial of creatine in amyotrophic lateral sclerosis
暂无分享,去创建一个
J. Veldink | H. Franssen | I. van der Tweel | J. Wokke | M. de Visser | Geert Jan Groeneveld | S. Kalmijn | C. Beijer | L. H. Berg
[1] W. Hemmer,et al. Creatine kinase in non-muscle tissues and cells , 1994, Molecular and Cellular Biochemistry.
[2] T. Wallimann,et al. Creatine supplementation in health and disease. Effects of chronic creatine ingestion in vivo: Down-regulation of the expression of creatine transporter isoforms in skeletal muscle , 1998, Molecular and Cellular Biochemistry.
[3] E. Schon,et al. Mitochondrial DNA and respiratory chain function in spinal cords of ALS patients , 2002, Journal of neurochemistry.
[4] Jeffrey D. Rothstein,et al. From charcot to lou gehrig: deciphering selective motor neuron death in als , 2001, Nature Reviews Neuroscience.
[5] G. Mora,et al. Effects of creatine supplementation on exercise performance and muscular strength in amyotrophic lateral sclerosis: preliminary results , 2001, Journal of the Neurological Sciences.
[6] O. Andreassen,et al. Creatine Increases Survival and Delays Motor Symptoms in a Transgenic Animal Model of Huntington's Disease , 2001, Neurobiology of Disease.
[7] A Whitehead,et al. Interim analyses and sequential designs in phase III studies. , 2001, British journal of clinical pharmacology.
[8] M. Beal,et al. Potential for creatine and other therapies targeting cellular energy dysfunction in neurological disorders , 2001, Annals of neurology.
[9] J. Whitehead. Monotherapy trials: sequential design , 2001, Epilepsy Research.
[10] A. Schapira,et al. Mitochondrial dysfunction in neurodegenerative disorders and ageing. , 2001, Advances in experimental medicine and biology.
[11] O. Andreassen,et al. Creatine increase survival and delays motor symptoms in a transgenic animal model of Huntington's disease. , 2001, Neurobiology of disease.
[12] M. Mattson,et al. Dietary supplement creatine protects against traumatic brain injury , 2000, Annals of neurology.
[13] M. Beal. Energetics in the pathogenesis of neurodegenerative diseases , 2000, Trends in Neurosciences.
[14] E. Joosten,et al. Chronic Mitochondrial Inhibition Induces Selective Motoneuron Death In Vitro: A New Model for Amyotrophic Lateral Sclerosis , 2000, Journal of neurochemistry.
[15] M. Tarnopolsky,et al. Acute creatine loading increases fat-free mass, but does not affect blood pressure, plasma creatinine, or CK activity in men and women. , 2000, Medicine and science in sports and exercise.
[16] M. Dalakas,et al. Viral hide-and-seek in sporadic ALS , 2000, Neurology.
[17] M. Swash,et al. El Escorial revisited: Revised criteria for the diagnosis of amyotrophic lateral sclerosis , 2000, Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases.
[18] R. Harris. Effects and Safety of Dietary and Supplementary Creatine , 2000 .
[19] Margaret A. Johnson,et al. Mitochondrial enzyme activity in amyotrophic lateral sclerosis: Implications for the role of mitochondria in neuronal cell death , 1999, Annals of neurology.
[20] J. Frahm,et al. Brain water diffusion in normal and creatine‐supplemented rats during transient global ischemia , 1999, Magnetic resonance in medicine.
[21] M. Tarnopolsky,et al. Creatine monohydrate increases strength in patients with neuromuscular disease , 1999, Neurology.
[22] Ole A. Andreassen,et al. Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis , 1999, Nature Medicine.
[23] B P Gardner,et al. Efficacy and safety of oral sildenafil (Viagra) in men with erectile dysfunction caused by spinal cord injury , 1998, Neurology.
[24] M. Mattson,et al. Protein modification by the lipid peroxidation product 4‐hydroxynonenal in the spinal cords of amyotrophic lateral sclerosis patients , 1998, Annals of neurology.
[25] C. Armon,et al. Linear estimates of rates of disease progression as predictors of survival in patients with ALS entering clinical trials 1 Presented in part at the 8th International Symposium on ALS/MND held in Glasgow, Scotland, November 3–5th, 1997. 1 , 1998, Journal of the Neurological Sciences.
[26] Gary L. Pattee,et al. Mitochondria in Sporadic Amyotrophic Lateral Sclerosis , 1998, Experimental Neurology.
[27] J. Kong,et al. Massive Mitochondrial Degeneration in Motor Neurons Triggers the Onset of Amyotrophic Lateral Sclerosis in Mice Expressing a Mutant SOD1 , 1998, The Journal of Neuroscience.
[28] W. Kunz,et al. Impairment of mitochondrial function in skeletal muscle of patients with amyotrophic lateral sclerosis , 1998, Journal of the Neurological Sciences.
[29] M. Tarnopolsky,et al. A randomized, controlled trial of creatine monohydrate in patients with mitochondrial cytopathies , 1997, Muscle & nerve.
[30] C. Bosco,et al. Effect of Oral Creatine Supplementation on Jumping and Running Performance , 1997, International journal of sports medicine.
[31] G. Parry,et al. Placebo-controlled trial of gabapentin in patients with amyotrophic lateral sclerosis , 1996, Neurology.
[32] T. Wallimann,et al. Differential effects of creatine depletion on the regulation of enzyme activities and on creatine-stimulated mitochondrial respiration in skeletal muscle, heart, and brain. , 1996, Biochimica et biophysica acta.
[33] P. Andres,et al. A comparison of three measures of disease progression in ALS , 1996, Journal of the Neurological Sciences.
[34] P. Leigh,et al. Dose-ranging study of riluzole in amyotrophic lateral sclerosis , 1996, The Lancet.
[35] M. Gurney,et al. Benefit of vitamin E, riluzole, and gababapentin in a transgenic model of familial amyotrophic lateral sclerosis , 1996, Annals of neurology.
[36] G. Parry,et al. Placebo-controlled trial of gabapentin in patients with amyotrophic lateral sclerosis. WALS Study Group. Western Amyotrophic Lateral Sclerosis Study Group. , 1996, Neurology.
[37] P. Leigh,et al. Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis/Riluzole Study Group II. , 1996, Lancet.
[38] A. Levey,et al. Selective loss of glial glutamate transporter GLT‐1 in amyotrophic lateral sclerosis , 1995, Annals of neurology.
[39] S H Appel,et al. Natural history of amyotrophic lateral sclerosis in a database population. Validation of a scoring system and a model for survival prediction. , 1995, Brain : a journal of neurology.
[40] D. Borchelt,et al. An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria , 1995, Neuron.
[41] C. Earnest,et al. The effect of creatine monohydrate ingestion on anaerobic power indices, muscular strength and body composition. , 1995, Acta physiologica Scandinavica.
[42] V. Meininger,et al. A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group. , 1994, The New England journal of medicine.
[43] A. Pestronk,et al. Trial of immunosuppression in amyotrophic lateral sclerosis using total lymphoid irradiation , 1994, Annals of neurology.
[44] C. Beyer. Creatine measurement in serum and urine with an automated enzymatic method. , 1993, Clinical chemistry.
[45] E Hultman,et al. Influence of oral creatine supplementation of muscle torque during repeated bouts of maximal voluntary exercise in man. , 1993, Clinical science.
[46] W. Hemmer,et al. Functional aspects of creatine kinase in brain. , 1993, Developmental neuroscience.
[47] E Hultman,et al. Elevation of creatine in resting and exercised muscle of normal subjects by creatine supplementation. , 1992, Clinical science.
[48] C. Sherbourne,et al. The MOS 36-Item Short-Form Health Survey (SF-36) , 1992 .
[49] Ware J.E.Jr.,et al. THE MOS 36- ITEM SHORT FORM HEALTH SURVEY (SF- 36) CONCEPTUAL FRAMEWORK AND ITEM SELECTION , 1992 .
[50] M. Palmer. Clinical Trials: A Practical Approach , 1985 .
[51] L. Freedman. Tables of the number of patients required in clinical trials using the logrank test. , 1982, Statistics in medicine.