Increased sensitivity of the microsomal oxidation of ethanol to inhibition by pyrazole and 4-methylpyrazole after chronic ethanol treatment.

[1]  A. Cederbaum,et al.  Inhibition of microsomal oxidation of ethanol by pyrazole and 4-methylpyrazole in vitro. Increased effectiveness after induction by pyrazole and 4-methylpyrazole. , 1986, The Biochemical journal.

[2]  G. Krikun,et al.  Rat liver microsomal induction of the oxidation of drugs and alcohols, and sodium dodecyl sulfate-gel profiles after in vivo treatment with pyrazole or 4-methylpyrazole. , 1986, Journal of Pharmacology and Experimental Therapeutics.

[3]  A. Cederbaum,et al.  Interaction of pyrazole and 4-methylpyrazole with hepatic microsomes: effect on cytochrome P-450 content, microsomal oxidation of alcohols, and binding spectra. , 1985, Alcoholism, clinical and experimental research.

[4]  M. J. Coon,et al.  Metabolism of nitrosamines by purified rabbit liver cytochrome P-450 isozymes. , 1985, Cancer research.

[5]  A. Cederbaum,et al.  Increased content of cytochrome P-450 and 4-methylpyrazole binding spectrum after 4-methylpyrazole treatment. , 1985, Biochemical and biophysical research communications.

[6]  C. Lieber.  Alcohol and the Liver: 1984 Update , 1984, Hepatology.

[7]  G. Krikun,et al.  Increased microsomal oxidation of alcohols after pyrazole treatment and its similarities to the induction by ethanol consumption. , 1984, Biochimica et biophysica acta.

[8]  C. Lieber.  Microsomal ethanol oxidizing system (MEOS): Interaction with ethanol, drugs and carcinogens , 1983, Pharmacology Biochemistry and Behavior.

[9]  A. Cederbaum,et al.  The effect of EDTA and iron on the oxidation of hydroxyl radical scavenging agents and ethanol by rat liver microsomes. , 1983, Biochemical and biophysical research communications.

[10]  M. J. Coon,et al.  Catalytic activity of cytochrome P-450 isozyme 3a isolated from liver microsomes of ethanol-treated rabbits. Oxidation of alcohols. , 1982, The Journal of biological chemistry.

[11]  C. Lieber,et al.  The feeding of alcohol in liquid diets: two decades of applications and 1982 update. , 1982, Alcoholism, clinical and experimental research.

[12]  S. Damgaard.  The D(V/K) isotope effect of the cytochrome P-450-mediated oxidation of ethanol and its biological applications. , 1982, European journal of biochemistry.

[13]  A. Cederbaum,et al.  Pyrazole and 4-methylpyrazole inhibit oxidation of ethanol and dimethyl sulfoxide by hydroxyl radicals generated from ascorbate, xanthine oxidase, and rat liver microsomes. , 1982, Archives of biochemistry and biophysics.

[14]  E. Haliday,et al.  Induction of microsomal dimethylnitrosamine demethylase by pyrazole. , 1982, Biochemical Pharmacology.

[15]  C. S. Yang,et al.  Pyrazole-induced cytochrome P-450 in rat liver microsomes: an isozyme with high affinity for dimethylnitrosamine. , 1981, Biochemical and biophysical research communications.

[16]  C. Lieber,et al.  Reconstitution of the microsomal ethanol-oxidizing system. Qualitative and quantitative changes of cytochrome P-450 after chronic ethanol consumption. , 1977, The Journal of biological chemistry.

[17]  G. Powis,et al.  The effect of inhibitors of alcohol metabolism upon the changes in the hepatic microsomal metabolism of foreign compounds produced by the acute administration of some alcohols to the rat. , 1976, Biochemical pharmacology.

[18]  R. Rognstad.  Isotopic probes into pathways of ethanol metabolism. , 1974, Archives of biochemistry and biophysics.

[19]  C. Lieber,et al.  Interaction of ethanol and pyrazole with hepatic microsomes. , 1971, Biochemical and biophysical research communications.

[20]  C. Lieber,et al.  Effects of pyrazole on hepatic function and structure. , 1970, Laboratory investigation; a journal of technical methods and pathology.

[21]  C. Lieber,et al.  Hepatic microsomal ethanol-oxidizing system. In vitro characteristics and adaptive properties in vivo. , 1970, The Journal of biological chemistry.

[22]  U. Rydberg,et al.  Inhibition of ethanol metabolism in vivo by administration of pyrazole. , 1969, Biochemical pharmacology.

[23]  Ting-kai Li,et al.  Human liver alcohol dehydrogenase: inhibition by pyrazole and pyrazole analogs. , 1969, Acta chemica Scandinavica.

[24]  M. Anbar,et al.  A compilation of specific bimolecular rate constants for the reactions of hydrated electrons, hydrogen atoms and hydroxyl radicals with inorganic and organic compounds in aqueous solution , 1967 .