A 56-year-old man complaining of body weight loss and epigastric pain was referred to the hospital with a diagnosis of advanced gastric cancer. The patient also had diabetes mellitus and protein level in the urine was 8.04g/day on admission. Administration of albumin and FFP was performed before operation, followed by subtotal gastrectomy and biopsy of the kidney. Albumin and FFP regimen was continued after the operation. Urinary protein level started to decrease on the second postoperative week to be 3.9g/day on the third month. Histologically the gastric cancer was poorly to moderately differentiated adenocarcinoma, and the lesion of the kidney was diagnosed as membranous nephropathy. No clear histologic deposits of CEA to glomerula were shown, but a strong correlation between CEA immunocomplex and membranous nephropathy was suggested. As far as we could review, such cases as operation for gastric cancer resulted in remission of nephrotic syndrome have come to eight cases. If we set limit the histologic type of the kidney to membranous nephropathy alone, all cases undergoing operation for gastric cancer experienced a remission of nephrotic syndrome.
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