From Simulation Chips to Biomedical Simulators

Computer simulation in physiology is an interdisciplinary problem. It is very important to provide good readability of used models. Programmer understands the architecture of models and the algorithms of programs. On the other hand physiologist usually can judge how closely the behavio of system correspond to the nature. In this text we will show how some known programming methods can help us find common language between programmers and physicians. Simulation models Simulation models in physiology are based on differential equations, regulation mechanisms and often on some mathematical algorithms like finding value of inverse function or solving some optimization problem. In scientific literature there are many articles about partial simulation models programmed in classical sequential languages like FORTRAN, MODULA, ADA, etc. Those products are hardly understandable for physiologists and non-programmers. Speak nothing of linear structure of these programs, which usually excludes any updating, adaptations or expansion. For these reasons our team found another way. We use MATLAB & SIMULINK graphical programming environment. This software is developed for use in control industry and for using advanced mathematical methods and has a strong toolset for constructing, developing and testing of various models.