CD95's deadly mission in the immune system

[1]  P. Krammer,et al.  TCR-Mediated Up-Regulation of c-FLIPshort Correlates with Resistance Toward CD95-Mediated Apoptosis by Blocking Death-Inducing Signaling Complex Activity1 , 2000, The Journal of Immunology.

[2]  H. Shu,et al.  B cell maturation protein is a receptor for the tumor necrosis factor family member TALL-1. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[3]  Xiaodong Wang,et al.  Smac, a Mitochondrial Protein that Promotes Cytochrome c–Dependent Caspase Activation by Eliminating IAP Inhibition , 2000, Cell.

[4]  Robert L Moritz,et al.  Identification of DIABLO, a Mammalian Protein that Promotes Apoptosis by Binding to and Antagonizing IAP Proteins , 2000, Cell.

[5]  J. Treanor,et al.  Taci Is a Traf-Interacting Receptor for Tall-1, a Tumor Necrosis Factor Family Member Involved in B Cell Regulation , 2000, The Journal of experimental medicine.

[6]  R M Siegel,et al.  A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling. , 2000, Science.

[7]  J K Frederiksen,et al.  Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations. , 2000, Science.

[8]  J. Blenis,et al.  FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2. , 2000, Immunity.

[9]  D. Lawrence,et al.  Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5. , 2000, Immunity.

[10]  D. Goeddel,et al.  Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development. , 2000, Immunity.

[11]  V. Dixit,et al.  Interaction of the TNF homologues BLyS and APRIL with the TNF receptor homologues BCMA and TACI , 2000, Current Biology.

[12]  B. Chain,et al.  How can dendritic cells cause autoimmune disease? , 2000, Immunology today.

[13]  G. Remuzzi,et al.  Thymic Dendritic Cells Express Inducible Nitric Oxide Synthase and Generate Nitric Oxide in Response to Self- and Alloantigens1 , 2000, The Journal of Immunology.

[14]  Don Foster,et al.  TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease , 2000, Nature.

[15]  J. Sprent,et al.  The thymus and central tolerance. , 2000, Clinical immunology.

[16]  J. Tschopp,et al.  TRAIL receptor-2 signals apoptosis through FADD and caspase-8 , 2000, Nature Cell Biology.

[17]  P. Krammer,et al.  Tumor counterattack – concept and reality , 2000, European journal of immunology.

[18]  A. Strasser,et al.  FADD/MORT1 regulates the pre‐TCR checkpoint and can function as a tumour suppressor , 2000, The EMBO journal.

[19]  R. Steinman,et al.  The Induction of Tolerance by Dendritic Cells That Have Captured Apoptotic Cells , 2000, The Journal of experimental medicine.

[20]  Kenneth G. C. Smith,et al.  bcl-2 Transgene Expression Inhibits Apoptosis in the Germinal Center and Reveals Differences in the Selection of Memory B Cells and Bone Marrow Antibody-Forming Cells , 2000, The Journal of experimental medicine.

[21]  P. Krammer,et al.  Critical role for mitochondria in B cell receptor‐mediated apoptosis , 2000 .

[22]  D. Baltimore,et al.  Autoimmunity as a consequence of retrovirus-mediated expression of C-FLIP in lymphocytes. , 2009, Immunity.

[23]  L. Montagnier,et al.  Programmed Cell Death as a Mechanism of CD4 and CD8 T Cell Deletion in AIDS: Molecular Control and Effect of Highly Active Anti‐retroviral Therapy , 1999, Annals of the New York Academy of Sciences.

[24]  P. Krammer CD95(APO-1/Fas)-mediated apoptosis: live and let die. , 1999, Advances in immunology.

[25]  K. Elkon,et al.  Dendritic cells are resistant to apoptosis through the Fas (CD95/APO-1) pathway. , 1999, Journal of immunology.

[26]  T. Defrance,et al.  Mitochondria connects the antigen receptor to effector caspases during B cell receptor-induced apoptosis in normal human B cells. , 1999, Journal of immunology.

[27]  K. Schooley,et al.  Human Dendritic Cells Mediate Cellular Apoptosis via Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (Trail) , 1999, The Journal of experimental medicine.

[28]  A. Strasser,et al.  Transgenic models of lymphoid neoplasia and development of a pan-hematopoietic vector , 1999, Oncogene.

[29]  I. Berberich,et al.  Reversal of Blimp‐1‐mediated apoptosis by A1, a member of the Bcl‐2 family , 1999, European journal of immunology.

[30]  D. Baltimore,et al.  Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death. , 1999, Immunity.

[31]  S. Korsmeyer,et al.  Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis , 1999, Nature.

[32]  J. Miller,et al.  A central role for thymic emigrants in peripheral T cell homeostasis. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[33]  M. Martínez-Lorenzo,et al.  Activated human T cells release bioactive Fas ligand and APO2 ligand in microvesicles. , 1999, Journal of immunology.

[34]  I. Iwamoto,et al.  Primed T cells are more resistant to Fas-mediated activation-induced cell death than naive T cells. , 1999, Journal of immunology.

[35]  J. Puck,et al.  Inherited Human Caspase 10 Mutations Underlie Defective Lymphocyte and Dendritic Cell Apoptosis in Autoimmune Lymphoproliferative Syndrome Type II , 1999, Cell.

[36]  P. Marrack,et al.  Reactive oxygen species regulate activation-induced T cell apoptosis. , 1999, Immunity.

[37]  R G Miller,et al.  A role for perforin in activation-induced T cell death in vivo: increased expansion of allogeneic perforin-deficient T cells in SCID mice. , 1999, Journal of immunology.

[38]  E. Clark,et al.  Signal transduction pathways that regulate the fate of B lymphocytes. , 1999, Advances in immunology.

[39]  M. Bachmann,et al.  Selection of the T cell repertoire. , 1999, Annual review of immunology.

[40]  K. Debatin Activation of apoptosis pathways by anticancer drugs. , 1999, Advances in experimental medicine and biology.

[41]  Z. Wang,et al.  Bisindolylmaleimide VIII facilitates Fas-mediated apoptosis and inhibits T cell-mediated autoimmune diseases , 1999, Nature Medicine.

[42]  E. Shevach,et al.  Peripheral T-cell self-reactivity and immunological memory. , 1998, Immunology today.

[43]  K. Rajewsky,et al.  Rapid elimination of mature autoreactive B cells demonstrated by Cre-induced change in B cell antigen receptor specificity in vivo. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[44]  J. H. Li,et al.  The regulation of CD95 ligand expression and function in CTL. , 1998, Journal of immunology.

[45]  P. Krammer,et al.  CXCR4 and CD4 mediate a rapid CD95-independent cell death in CD4(+) T cells. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[46]  A. Kruisbeek,et al.  Thymocyte selection: not by TCR alone , 1998, Immunological reviews.

[47]  Xiaodong Wang,et al.  Bid, a Bcl2 Interacting Protein, Mediates Cytochrome c Release from Mitochondria in Response to Activation of Cell Surface Death Receptors , 1998, Cell.

[48]  Junying Yuan,et al.  Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis , 1998, Cell.

[49]  J. Sprent,et al.  A Role for Fas in Negative Selection of Thymocytes In Vivo , 1998, The Journal of experimental medicine.

[50]  M. Peter,et al.  Two CD95 (APO‐1/Fas) signaling pathways , 1998, The EMBO journal.

[51]  A. Marshak‐Rothstein,et al.  Tolerant B Lymphocytes Acquire Resistance to Fas-mediated Apoptosis after Treatment with Interleukin 4 but Not after Treatment with Specific Antigen Unless a Surface Immunoglobulin Threshold Is Exceeded , 1998, The Journal of experimental medicine.

[52]  M. Albert,et al.  Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs , 1998, Nature.

[53]  S. Nagata Human autoimmune lymphoproliferative syndrome, a defect in the apoptosis-inducing Fas receptor: A lesson from the mouse model , 1998, Journal of Human Genetics.

[54]  B. Nelson,et al.  Biology of the interleukin-2 receptor. , 1998, Advances in immunology.

[55]  D. Chao,et al.  BCL-2 family: regulators of cell death. , 1998, Annual review of immunology.

[56]  T. Ochi,et al.  Membrane Fas Ligand Kills Human Peripheral Blood T Lymphocytes, and Soluble Fas Ligand Blocks the Killing , 1997, The Journal of experimental medicine.

[57]  M. Peter,et al.  Cleavage of FLICE (caspase‐8) by granzyme B during cytotoxic T lymphocyte‐induced apoptosis , 1997, European journal of immunology.

[58]  K. Rajewsky,et al.  In Vivo Ablation of Surface Immunoglobulin on Mature B Cells by Inducible Gene Targeting Results in Rapid Cell Death , 1997, Cell.

[59]  V. Dixit,et al.  A Novel Family of Viral Death Effector Domain-containing Molecules That Inhibit Both CD-95- and Tumor Necrosis Factor Receptor-1-induced Apoptosis* , 1997, The Journal of Biological Chemistry.

[60]  J. Tschopp,et al.  Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors , 1997, Nature.

[61]  J. Banchereau,et al.  CD40 ligation counteracts Fas-induced apoptosis of human dendritic cells. , 1997, International immunology.

[62]  P. Golstein Controlling Cell Death , 1997, Science.

[63]  J. Bertin,et al.  Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas- and TNFR1-induced apoptosis. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[64]  I. Herr,et al.  Activation of the CD95 (APO-1/Fas) system in T cells from human immunodeficiency virus type-1-infected children. , 1996, Blood.

[65]  Matthias Mann,et al.  FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex , 1996, Cell.

[66]  P. Krammer,et al.  Concurrent engagement of CD40 and the antigen receptor protects naive and memory human B cells from APO-1/Fas-mediated apoptosis , 1996, The Journal of experimental medicine.

[67]  H. Pircher,et al.  Visualization, characterization, and turnover of CD8+ memory T cells in virus-infected hosts , 1996, The Journal of experimental medicine.

[68]  A. Abbas,et al.  The roles of costimulation and Fas in T cell apoptosis and peripheral tolerance. , 1996, Immunity.

[69]  A. H. Drummond,et al.  Fas ligand in human serum , 1996, Nature Medicine.

[70]  J. Banchereau,et al.  Bcl-2+ tonsillar plasma cells are rescued from apoptosis by bone marrow fibroblasts , 1996, The Journal of experimental medicine.

[71]  M. Peter,et al.  Cytotoxicity‐dependent APO‐1 (Fas/CD95)‐associated proteins form a death‐inducing signaling complex (DISC) with the receptor. , 1995, The EMBO journal.

[72]  C. Thompson,et al.  CD28 and apoptosis. , 1995, Current opinion in immunology.

[73]  M. Lenardo,et al.  Induction of apoptosis in mature T cells by tumour necrosis factor , 1995, Nature.

[74]  P. Krammer,et al.  Regulation of cell surface APO‐1/Fas (CD95) ligand expression by metalloproteases , 1995, European journal of immunology.

[75]  S. Hanabuchi,et al.  Fas‐mediated Cytotoxicity ‐ A New Immunoregulatory and Pathogenic Function of Thl CD4+ T Cells , 1995, Immunological reviews.

[76]  Warren Strober,et al.  Dominant interfering fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome , 1995, Cell.

[77]  P. Krammer,et al.  Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120 , 1995, Nature.

[78]  F. Rieux-Laucat,et al.  Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity. , 1995, Science.

[79]  V. Metelev,et al.  Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat protein. , 1995, Science.

[80]  G. Fiucci,et al.  Three functional soluble forms of the human apoptosis-inducing Fas molecule are produced by alternative splicing. , 1995, Journal of immunology.

[81]  Masato Tanaka,et al.  Expression of the functional soluble form of human fas ligand in activated lymphocytes. , 1995, The EMBO journal.

[82]  S. Ju,et al.  Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation , 1995, Nature.

[83]  Seamus J. Martin,et al.  Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas , 1995, Nature.

[84]  P. Krammer,et al.  Autocrine T-cell suicide mediated by APO-1/(Fas/CD95) , 1995, Nature.

[85]  T. Curiel,et al.  Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes , 1995, Nature Medicine.

[86]  C. Smith,et al.  Fas ligand mediates activation-induced cell death in human T lymphocytes , 1995, The Journal of experimental medicine.

[87]  G. Kroemer The pharmacology of T cell apoptosis. , 1995, Advances in immunology.

[88]  M. Peter,et al.  The Role of APO‐1‐Mediated Apoptosis in the Immune System , 1994, Immunological reviews.

[89]  J. Sprent,et al.  T-cell apoptosis detected in situ during positive and negative selection in the thymus , 1994, Nature.

[90]  A. Abbas,et al.  The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice. , 1994, Immunity.

[91]  A. Benner,et al.  High expression of APO-1 (CD95) on T lymphocytes from human immunodeficiency virus-1-infected children. , 1994, Blood.

[92]  P. Krammer,et al.  Activation interferes with the APO-1 pathway in mature human T cells. , 1993, International immunology.

[93]  K. Koretz,et al.  Constitutive and induced expression of APO-1, a new member of the nerve growth factor/tumor necrosis factor receptor superfamily, in normal and neoplastic cells. , 1993, Laboratory investigation; a journal of technical methods and pathology.

[94]  P. Krammer,et al.  When apoptosis fails , 1992, Current Biology.

[95]  S. Tonegawa Somatic generation of antibody diversity , 1983, Nature.

[96]  W. F. Chen,et al.  The size of functional T-lymphocyte pools within thymic medullary and cortical cell subsets. , 1983, Thymus.