Intronic hormone response elements mediate regulation of FKBP5 by progestins and glucocorticoids

[1]  R. Kemppainen,et al.  Identification of a glucocorticoid response element in the 3'-flanking region of the human Dexras1 gene. , 2003, Biochimica et biophysica acta.

[2]  Joyce Cheung-Flynn,et al.  The FK506-binding immunophilin FKBP51 is transcriptionally regulated by progestin and attenuates progestin responsiveness. , 2003, Endocrinology.

[3]  J. Scammell,et al.  Organization of the human FK506-binding immunophilin FKBP52 protein gene (FKBP4). , 2003, Genomics.

[4]  S. Palumbi,et al.  High intron sequence conservation across three mammalian orders suggests functional constraints. , 2003, Molecular biology and evolution.

[5]  S. Nordeen,et al.  CBP recruitment and histone acetylation in differential gene induction by glucocorticoids and progestins. , 2003, Molecular endocrinology.

[6]  J. Richards,et al.  Egr-1 induction in rat granulosa cells by follicle-stimulating hormone and luteinizing hormone: combinatorial regulation by transcription factors cyclic adenosine 3',5'-monophosphate regulatory element binding protein, serum response factor, sp1, and early growth response factor-1. , 2003, Molecular endocrinology.

[7]  Zhou Wang,et al.  Identification of androgen-responsive genes in the rat ventral prostate by complementary deoxyribonucleic acid subtraction and microarray. , 2003, Endocrinology.

[8]  K. Alitalo,et al.  Transcriptional regulation of the ornithine decarboxylase gene by c-Myc/Max/Mad network and retinoblastoma protein interacting with c-Myc. , 2003, The international journal of biochemistry & cell biology.

[9]  P. A. Wood,et al.  A Thyroid Hormone Response Unit Formed between the Promoter and First Intron of the Carnitine Palmitoyltransferase-Iα Gene Mediates the Liver-specific Induction by Thyroid Hormone* , 2003, The Journal of Biological Chemistry.

[10]  D. Picard,et al.  The Hsp90‐binding peptidylprolyl isomerase FKBP52 potentiates glucocorticoid signaling in vivo , 2003, The EMBO journal.

[11]  Frank Claessens,et al.  Selective DNA recognition by the androgen receptor as a mechanism for hormone-specific regulation of gene expression. , 2003, Molecular genetics and metabolism.

[12]  J. R. Campbell,et al.  Glucocorticoids stimulate human sgk1 gene expression by activation of a GRE in its 5'-flanking region. , 2002, American journal of physiology. Endocrinology and metabolism.

[13]  W. Vainchenker,et al.  Overexpression of FKBP51 in idiopathic myelofibrosis regulates the growth factor independence of megakaryocyte progenitors. , 2002, Blood.

[14]  Y. Wan,et al.  Overlapping but distinct gene regulation profiles by glucocorticoids and progestins in human breast cancer cells. , 2002, Molecular endocrinology.

[15]  K. Horwitz,et al.  Differential Gene Regulation by the Two Progesterone Receptor Isoforms in Human Breast Cancer Cells* , 2002, The Journal of Biological Chemistry.

[16]  D. Ray,et al.  Failure of steroid regulation of the MMTV promoter in a small cell lung cancer cell line is caused by a DNA sequence flanking the glucocorticoid response element. , 2002, The Journal of endocrinology.

[17]  W. Pratt,et al.  Evidence for a Mechanism of Repression of Heat Shock Factor 1 Transcriptional Activity by a Multichaperone Complex* , 2001, The Journal of Biological Chemistry.

[18]  D. F. Smith,et al.  Overexpression of the FK506-binding immunophilin FKBP51 is the common cause of glucocorticoid resistance in three New World primates. , 2001, General and comparative endocrinology.

[19]  M. Estacion,et al.  Regulation of Drosophila TRPL Channels by Immunophilin FKBP59* , 2001, The Journal of Biological Chemistry.

[20]  Spyro Mousses,et al.  Failure of hormone therapy in prostate cancer involves systematic restoration of androgen responsive genes and activation of rapamycin sensitive signaling , 2001, Oncogene.

[21]  Sridhar Hannenhalli,et al.  Enrichment of regulatory signals in conserved non-coding genomic sequence , 2001, Bioinform..

[22]  C. Young,et al.  Silymarin inhibits function of the androgen receptor by reducing nuclear localization of the receptor in the human prostate cancer cell line LNCaP. , 2001, Carcinogenesis.

[23]  R. Minchin,et al.  Estradiol-regulated expression of the immunophilins cyclophilin 40 and FKBP52 in MCF-7 breast cancer cells. , 2001, Biochemical and biophysical research communications.

[24]  M. Galigniana,et al.  Evidence That the Peptidylprolyl Isomerase Domain of the hsp90-binding Immunophilin FKBP52 Is Involved in Both Dynein Interaction and Glucocorticoid Receptor Movement to the Nucleus* , 2001, The Journal of Biological Chemistry.

[25]  R. Loftus,et al.  The alpha-subunit of the epithelial sodium channel is an aldosterone-induced transcript in mammalian collecting ducts, and this transcriptional response is mediated via distinct cis-elements in the 5'-flanking region of the gene. , 2001, Molecular endocrinology.

[26]  L. Pennacchio,et al.  Genomic strategies to identify mammalian regulatory sequences , 2001, Nature Reviews Genetics.

[27]  S. Hendy,et al.  Two Classes of Androgen Receptor Elements Mediate Cooperativity through Allosteric Interactions* , 2001, The Journal of Biological Chemistry.

[28]  L. Hersh,et al.  Identification and characterization of two androgen response regions in the human neutral endopeptidase gene , 2000, Molecular and Cellular Endocrinology.

[29]  L. Sapinoso,et al.  Functional dissection of transcriptional profiles in androgen-dependent and -independent prostate cancer , 2001, Nature Genetics.

[30]  D. F. Smith,et al.  Molecular chaperone interactions with steroid receptors: an update. , 2000, Molecular endocrinology.

[31]  B. Katzenellenbogen,et al.  Regulation of keratin 19 gene expression by estrogen in human breast cancer cells and identification of the estrogen responsive gene region , 2000, Molecular and Cellular Endocrinology.

[32]  G. Stancel,et al.  Identification of functional estrogen response elements in the gene coding for the potent angiogenic factor vascular endothelial growth factor. , 2000, Cancer research.

[33]  J. Hiscott,et al.  Posttranslational regulation of IRF-4 activity by the immunophilin FKBP52. , 2000, Immunity.

[34]  V. Casolaro,et al.  Glucocorticoids Inhibit Calcium- and Calcineurin-Dependent Activation of the Human IL-4 Promoter1 , 2000, The Journal of Immunology.

[35]  R. Shukin,et al.  Determinants of DNA sequence specificity of the androgen, progesterone, and glucocorticoid receptors: evidence for differential steroid receptor response elements. , 1999, Molecular endocrinology.

[36]  V. Pethe,et al.  Estrogen Inducibility of c-Ha-ras Transcription in Breast Cancer Cells , 1999, The Journal of Biological Chemistry.

[37]  Paul T. Tarr,et al.  Cooperative Assembly of Androgen Receptor into a Nucleoprotein Complex That Regulates the Prostate-specific Antigen Enhancer* , 1999, The Journal of Biological Chemistry.

[38]  Thomas L. Madden,et al.  BLAST 2 Sequences, a new tool for comparing protein and nucleotide sequences. , 1999, FEMS microbiology letters.

[39]  J. Stokes,et al.  Glucocorticoid Induction of Epithelial Sodium Channel Expression in Lung and Renal Epithelia Occurs via trans-Activation of a Hormone Response Element in the 5′-Flanking Region of the Human Epithelial Sodium Channel α Subunit Gene* , 1999, The Journal of Biological Chemistry.

[40]  K. Gautvik,et al.  Transcription of the human thyrotropin-releasing hormone receptor gene-analysis of basal promoter elements and glucocorticoid response elements. , 1999, Biochemical and biophysical research communications.

[41]  N. Wu,et al.  Regulation of human hsp90α gene expression , 1999, FEBS letters.

[42]  D. F. Smith,et al.  Glucocorticoid resistance in the squirrel monkey is associated with overexpression of the immunophilin FKBP51. , 1999, The Journal of clinical endocrinology and metabolism.

[43]  H. Samuels,et al.  Regulation of the mdm2 Oncogene by Thyroid Hormone Receptor , 1999, Molecular and Cellular Biology.

[44]  S. Nordeen,et al.  Differential gene induction by glucocorticoid and progesterone receptors , 1998, The Journal of Steroid Biochemistry and Molecular Biology.

[45]  J. Scammell,et al.  Glucocorticoid-resistant B-lymphoblast cell line derived from the Bolivian squirrel monkey (Saimiri boliviensis boliviensis). , 1998, Laboratory animal science.

[46]  N. Wu,et al.  Essential role of the first intron in the transcription of hsp90β gene , 1997, FEBS letters.

[47]  B. van der Burg,et al.  Novel Progesterone Target Genes Identified by an Improved Differential Display Technique Suggest That Progestin-induced Growth Inhibition of Breast Cancer Cells Coincides with Enhancement of Differentiation* , 1997, The Journal of Biological Chemistry.

[48]  W. Pratt,et al.  Steroid receptor interactions with heat shock protein and immunophilin chaperones. , 1997, Endocrine reviews.

[49]  Steven A. Carr,et al.  Pyridinyl Imidazole Inhibitors of p38 Mitogen-activated Protein Kinase Bind in the ATP Site* , 1997, The Journal of Biological Chemistry.

[50]  M. Martin,et al.  Tissue distribution and abundance of human FKBP51, and FK506-binding protein that can mediate calcineurin inhibition. , 1997, Biochemical and biophysical research communications.

[51]  Chawnshang Chang,et al.  Induction of the Intronic Enhancer of the Human Ciliary Neurotrophic Factor Receptor (CNTFRα) Gene by the TR4 Orphan Receptor , 1997, The Journal of Biological Chemistry.

[52]  R. Stein,et al.  Determinants of promoter-specific activity by glucocorticoid receptor. , 1996, Molecular endocrinology.

[53]  R. Day,et al.  Cell-specific expression of the rat secretogranin II promoter. , 1996, Endocrinology.

[54]  K. Hashinaka,et al.  Identification of transcriptional cis-elements in introns 7 and 9 of the myeloperoxidase gene. , 1993, The Journal of biological chemistry.

[55]  D. Edwards,et al.  The constitution of a progesterone response element. , 1993, Molecular endocrinology.

[56]  M. Parker,et al.  A consensus DNA-binding site for the androgen receptor. , 1992, Molecular endocrinology.

[57]  F. S. French,et al.  Response elements of the androgen-regulated C3 gene. , 1992, The Journal of biological chemistry.

[58]  C. Hutchison,et al.  Structural determinants of a glucocorticoid receptor recognition element. , 1990, Molecular endocrinology.

[59]  R. Klausner,et al.  Iron regulation of transferrin receptor mRNA levels requires iron‐responsive elements and a rapid turnover determinant in the 3′ untranslated region of the mRNA. , 1989, The EMBO journal.

[60]  J D Baxter,et al.  Glucocorticoid receptor binding and activation of a heterologous promoter by dexamethasone by the first intron of the human growth hormone gene , 1985, Molecular and cellular biology.

[61]  G. Chrousos,et al.  The squirrel monkey: receptor-mediated end-organ resistance to progesterone? , 1982, The Journal of clinical endocrinology and metabolism.

[62]  R. Vigersky,et al.  Glucocorticoid hormone resistance during primate evolution: receptor-mediated mechanisms. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[63]  Bart van der Burg,et al.  Glucocorticoid-induced increase in lymphocytic FKBP51 messenger ribonucleic acid expression: a potential marker for glucocorticoid sensitivity, potency, and bioavailability. , 2003, The Journal of clinical endocrinology and metabolism.

[64]  B. Kacinski,et al.  Hormonal regulation of the c‐fms proto‐oncogene in breast cancer cells is mediated by a composite glucocorticoid response element , 2002, Journal of cellular biochemistry.

[65]  T. Ratajczak,et al.  Human cyclophilin 40 is a heat shock protein that exhibits altered intracellular localization following heat shock , 2001, Cell stress & chaperones.

[66]  Mengqun Tan,et al.  Transgene Expression Transfer : Role of Cellular FKBP 52 Protein in Adeno-Associated Virus Type 2-Mediated Gene , 2001 .

[67]  J. Scammell.  Steroid resistance in the squirrel monkey: an old subject revisited. , 2000, ILAR journal.

[68]  David F. Smith,et al.  Printed in U.S.A. Copyright © 2000 by The Endocrine Society Squirrel Monkey Immunophilin FKBP51 Is a Potent Inhibitor of Glucocorticoid Receptor Binding* , 2000 .

[69]  D. Beyersmann,et al.  Regulation of mammalian gene expression. , 2000, EXS.

[70]  T. Werner,et al.  MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data. , 1995, Nucleic acids research.