Hepatic Encephalopathy in Patients with Cirrhosis
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[1] S. Sherlock,et al. Successful use of bromocriptine in the treatment of chronic hepatic encephalopathy. , 1980, Gastroenterology.
[2] J. Daurès,et al. [Lactulose-neomycin combination versus placebo in the treatment of acute hepatic encephalopathy. Results of a randomized controlled trial]. , 1994, Gastroenterologie clinique et biologique.
[3] S. Riordan,et al. Synbiotic modulation of gut flora: Effect on minimal hepatic encephalopathy in patients with cirrhosis , 2004, Hepatology.
[4] A. Lockwood,et al. Positron‐emission tomographic localization of abnormalities of brain metabolism in patients with minimal hepatic encephalopathy , 1993, Hepatology.
[5] M. Morgan,et al. Lactitol vs. lactulose in the treatment of acute hepatic encephalopathy in cirrhotic patients: A double‐blind, randomized trial , 1987, Hepatology.
[6] O. Riggio,et al. Simple tools for complex syndromes: a three-level difficulty test for hepatic encephalopathy. , 2012, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.
[7] G. Marchesini,et al. Branched-chain amino acids for people with hepatic encephalopathy. , 2017, The Cochrane database of systematic reviews.
[8] C. Leevy,et al. Rifaximin treatment in hepatic encephalopathy. , 2010, The New England journal of medicine.
[9] A. Chhibber,et al. The hyperventilation of cirrhosis: Progesterone and estradiol effects , 1997, Hepatology.
[10] Yong He,et al. Partial pressure of NH₃ in cirrhotic patients with and without hepatic encephalopathy. , 2011, Journal of gastrointestinal and liver diseases : JGLD.
[11] Lars Timmermann,et al. Critical flicker frequency for quantification of low‐grade hepatic encephalopathy , 2002, Hepatology.
[12] B. Sharma,et al. Critical flicker frequency: diagnostic tool for minimal hepatic encephalopathy. , 2007, Journal of hepatology.
[13] J. Guérit,et al. Spectral versus visual EEG analysis in mild hepatic encephalopathy , 1999, Clinical Neurophysiology.
[14] D. Freides,et al. Subclinical hepatic encephalopathy: detection, prevalence, and relationship to nitrogen metabolism. , 1978, Gastroenterology.
[15] R. Butterworth,et al. The neurosteroid system: Implication in the pathophysiology of hepatic encephalopathy , 2008, Neurochemistry International.
[16] J. Canales,et al. Chronic hyperammonemia alters motor and neurochemical responses to activation of group i metabotropic glutamate receptors in the nucleus accumbens in rats in vivo , 2003, Neurobiology of Disease.
[17] G. Barbarini,et al. Flumazenil for hepatic encephalopathy grade III and IVa in patients with cirrhosis: An italian multicenter double‐blind, placebo‐controlled, cross‐over study , 1998, Hepatology.
[18] R. Butterworth,et al. Effect of ammonium ions on synaptic transmission in the mammalian central nervous system , 1992, Progress in Neurobiology.
[19] R. Butterworth,et al. Manganese toxicity, dopaminergic dysfunction and hepatic encephalopathy , 1995, Metabolic Brain Disease.
[20] Y. Archibald,et al. The encephalopathy associated with septic illness. , 1990, Clinical and investigative medicine. Medecine clinique et experimentale.
[21] J. Wiltfang,et al. Neurophysiological assessment of early hepatic encephalopathy. , 1990, Electroencephalography and clinical neurophysiology.
[22] I. Ahmad,et al. L-ornithine-L-aspartate infusion efficacy in hepatic encephalopathy. , 2008, Journal of the College of Physicians and Surgeons--Pakistan : JCPSP.
[23] R. Butterworth,et al. Increased activities of MAOA and MAOB in autopsied brain tissue from cirrhotic patients with hepatic encephalopathy , 1993, Brain Research.
[24] C. Strassburg,et al. Cerebral white matter lesions in patients with cirrhosis – causative for hepatic encephalopathy or bystanders? , 2015, Liver international : official journal of the International Association for the Study of the Liver.
[25] C. Strassburg,et al. Cirrhosis-related Parkinsonism: prevalence, mechanisms and response to treatments. , 2013, Journal of hepatology.
[26] A. Webster,et al. Probiotics for people with hepatic encephalopathy. , 2017, The Cochrane database of systematic reviews.
[27] P. Lucatelli,et al. Management of refractory hepatic encephalopathy after insertion of TIPS: long-term results of shunt reduction with hourglass-shaped balloon-expandable stent-graft. , 2009, AJR. American journal of roentgenology.
[28] R. Butterworth,et al. Selective loss of pallidal dopamine D2 receptor density in hepatic encephalopathy , 1993, Neuroscience Letters.
[29] M. Merli,et al. Increased risk of cognitive impairment in cirrhotic patients with bacterial infections. , 2013, Journal of hepatology.
[30] À. Rovira,et al. 1H Magnetic Resonance in the Study of Hepatic Encephalopathy in Humans , 2002, Metabolic Brain Disease.
[31] M. Morgan,et al. Methods for Diagnosing Hepatic Encephalopathy in Patients with Cirrhosis: A Multidimensional Approach , 2004, Metabolic Brain Disease.
[32] T. Barrientos-Gutiérrez,et al. A systematic review and meta-analysis of the use of oral zinc in the treatment of hepatic encephalopathy , 2013, Nutrition Journal.
[33] E. Berry,et al. Cannabidiol ameliorates cognitive and motor impairments in mice with bile duct ligation. , 2009, Journal of hepatology.
[34] C. McClain,et al. Psychomotor performance defects in cirrhotic patients without overt encephalopathy. , 1980, Archives of internal medicine.
[35] D. V. van Thiel,et al. Subclinical hepatic encephalopathy. Comparison before and after orthotopic liver transplantation. , 1990, Transplantation.
[36] S. Sherlock,et al. The electroencephalograph in liver disease. , 1957, Lancet.
[37] Karl Zilles,et al. Neurotransmitter Receptor Imbalances in Motor Cortex and Basal Ganglia in Hepatic Encephalopathy , 2009, Cellular Physiology and Biochemistry.
[38] Manuel Romero-Gómez,et al. Value of the critical flicker frequency in patients with minimal hepatic encephalopathy , 2007, Hepatology.
[39] F. X. Aymerich,et al. Decreased white matter lesion volume and improved cognitive function after liver transplantation , 2007, Hepatology.
[40] P. Malfertheiner,et al. Oral L-ornithine-L-aspartate therapy of chronic hepatic encephalopathy: results of a placebo-controlled double-blind study. , 1998, Journal of hepatology.
[41] R. Hughes,et al. Ammonia and the neutrophil in the pathogenesis of hepatic encephalopathy in cirrhosis , 2010, Hepatology.
[42] K. Weissenborn. Diagnosis of Encephalopathy , 1998, Digestion.
[43] S. Dasarathy,et al. Sodium benzoate in the treatment of acute hepatic encephalopathy: A double‐blind randomized trial , 1992, Hepatology.
[44] M. Morgan,et al. Spatio-temporal decomposition of the electroencephalogram in patients with cirrhosis. , 2007, Journal of hepatology.
[45] P. V. Leeuwen,et al. NEW MODE OF ACTION FOR LACTULOSE , 1988, The Lancet.
[46] À. Rovira,et al. Brain magnetic resonance in hepatic encephalopathy. , 2014, Seminars in ultrasound, CT, and MR.
[47] M. Hashizume,et al. Portosystemic encephalopathy treated with balloon-occluded retrograde transvenous obliteration. , 1995, The American journal of gastroenterology.
[48] Philip Wong,et al. Hepatic encephalopathy in chronic liver disease: 2014 Practice Guideline by the American Association for the Study Of Liver Diseases and the European Association for the Study of the Liver , 2014, Hepatology.
[49] P. Ott,et al. Cerebral effects of ammonia in liver disease: current hypotheses , 2014, Metabolic Brain Disease.
[50] G. Kircheis,et al. Therapeutic efficacy of L‐ornithine‐L‐aspartate infusions in patients with cirrhosis and hepatic encephalopathy: Results of a placebo‐controlled, double‐blind study , 1997, Hepatology.
[51] R. Maffei,et al. Double-blind randomized clinical trial comparing neomycin and placebo in the treatment of exogenous hepatic encephalopathy. , 1992, Hepato-gastroenterology.
[52] S. Taylor-Robinson,et al. Regional variations in cerebral proton spectroscopy in patients with chronic hepatic encephalopathy , 1994, Metabolic Brain Disease.
[53] J. Bajaj,et al. Diagnosis of Minimal Hepatic Encephalopathy Using Stroop EncephalApp: A Multicenter US-Based, Norm-Based Study , 2016, The American Journal of Gastroenterology.
[54] R. Jalan,et al. Ornithine phenylacetate targets alterations in the expression and activity of glutamine synthase and glutaminase to reduce ammonia levels in bile duct ligated rats. , 2014, Journal of hepatology.
[55] R. Butterworth,et al. Diencephalic and cerebellar pathology in alcoholic and nonalcoholic patients with end‐stage liver disease , 1997, Hepatology.
[56] P. Angeli,et al. Covert hepatic encephalopathy: agreement and predictive validity of different indices. , 2014, World journal of gastroenterology.
[57] Focal neurological signs in hepatic encephalopathy in cirrhotic patients: an underestimated entity? , 2001 .
[58] M. Morgan,et al. Bromocriptine-associated ototoxicity , 1984, The Journal of Laryngology & Otology.
[59] C. Zwingmann,et al. L‐ornithine and phenylacetate synergistically produce sustained reduction in ammonia and brain water in cirrhotic rats , 2009, Hepatology.
[60] H. Hinterhuber,et al. Incomplete improvement of visuo‐motor deficits in patients with minimal hepatic encephalopathy after liver transplantation , 2004, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.
[61] V. Felipo,et al. Brain cholinergic impairment in liver failure , 2008, Brain : a journal of neurology.
[62] H. Wedemeyer,et al. The role of zinc in liver cirrhosis. , 2016 .
[63] M. Malaguarnera,et al. Effects of L-carnitine in patients with hepatic encephalopathy. , 2005, World journal of gastroenterology.
[64] N. Accornero,et al. High prevalence of spontaneous portal‐systemic shunts in persistent hepatic encephalopathy: A case‐control study , 2005, Hepatology.
[65] B. Jennett,et al. Assessment of coma and impaired consciousness. A practical scale. , 1974, Lancet.
[66] P. Angeli,et al. Clinical features and survivial of cirrhotic patients with subclinical cognitive alterations detected by the number connection test and computerized psychometric tests , 1999, Hepatology.
[67] S. Folstein,et al. "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. , 1975, Journal of psychiatric research.
[68] Alan H. Lockwood,et al. Blood Ammonia Levels and Hepatic Encephalopathy , 2004, Metabolic Brain Disease.
[69] R. Butterworth,et al. The nutritional management of hepatic encephalopathy in patients with cirrhosis: International society for hepatic encephalopathy and nitrogen metabolism consensus , 2013, Hepatology.
[70] F. Challenger,et al. Methyl mercaptan in relation to foetor hepaticus. , 1955, The Biochemical journal.
[71] P. Desjardins,et al. Evidence for oxidative/nitrosative stress in the pathogenesis of hepatic encephalopathy , 2010, Metabolic Brain Disease.
[72] K. Demır,et al. Are Acquired Hepatocerebral Degeneration and Hepatic Myelopathy Reversible? , 2009, Journal of clinical gastroenterology.
[73] S. Taylor-Robinson,et al. A longitudinal systems biology analysis of lactulose withdrawal in hepatic encephalopathy , 2012, Metabolic Brain Disease.
[74] M. Morgan. Cerebral Magnetic Resonance Imaging in Patients with Chronic Liver Disease , 1998, Metabolic Brain Disease.
[75] Klaus P. Ebmeier,et al. Regional cerebral blood flow and cognitive function in patients with chronic liver disease , 1991, The Lancet.
[76] R Fischer,et al. Hepatic encephalopathy in chronic liver disease: a clinical manifestation of astrocyte swelling and low-grade cerebral edema? , 2000, Journal of hepatology.
[77] M. Manns,et al. Liver transplantation improves hepatic myelopathy: evidence by three cases. , 2003, Gastroenterology.
[78] Y. Miyata,et al. Hepatic encephalopathy and reversible cortical blindness. , 1988, American Journal of Gastroenterology.
[79] P. Bisiacchi,et al. Improving the inhibitory control task to detect minimal hepatic encephalopathy. , 2010, Gastroenterology.
[80] K. Takeda,et al. Improvement of regional cerebral blood flow after treatment with branched‐chain amino acid solutions in patients with cirrhosis , 2003, European journal of gastroenterology & hepatology.
[81] A. Schnitzler,et al. Diagnostic and prognostic values of critical flicker frequency determination as new diagnostic tool for objective HE evaluation in patients undergoing TIPS implantation , 2009, European journal of gastroenterology & hepatology.
[82] B. Sharma,et al. Secondary prophylaxis of hepatic encephalopathy: an open-label randomized controlled trial of lactulose versus placebo. , 2009, Gastroenterology.
[83] Beiwen Zheng,et al. Alterations of the human gut microbiome in liver cirrhosis , 2014, Nature.
[84] F. Glocker,et al. Portosystemic myelopathy: Spastic paraparesis after portosystemic shunting , 2006, Scandinavian journal of gastroenterology.
[85] Edward T. Bullmore,et al. Functional brain network changes associated with clinical and biochemical measures of the severity of hepatic encephalopathy , 2015, NeuroImage.
[86] A. Lockwood,et al. Cerebral Ammonia Metabolism in Patients with Severe Liver Disease and Minimal Hepatic Encephalopathy , 1991, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[87] Ritesh Agarwal,et al. Lactulose improves cognitive functions and health‐related quality of life in patients with cirrhosis who have minimal hepatic encephalopathy , 2007, Hepatology.
[88] C. Leevy,et al. Hospitalizations During the Use of Rifaximin Versus Lactulose for the Treatment of Hepatic Encephalopathy , 2007, Digestive Diseases and Sciences.
[89] William M. Lee,et al. Persistence of cognitive impairment after resolution of overt hepatic encephalopathy. , 2010, Gastroenterology.
[90] R. Jalan,et al. Interorgan ammonia metabolism in liver failure: the basis of current and future therapies , 2011, Liver international : official journal of the International Association for the Study of the Liver.
[91] H. Figulla,et al. Portosystemic hepatic encephalopathy after transjugular intrahepatic portosystemic shunt in patients with cirrhosis: Clinical, laboratory, psychometric, and electroencephalographic investigations , 1998, Hepatology.
[92] Michael L Volk,et al. Hospital Readmissions Among Patients With Decompensated Cirrhosis , 2012, The American Journal of Gastroenterology.
[93] S. Saab,et al. Probiotics are helpful in hepatic encephalopathy: a meta‐analysis of randomized trials , 2016, Liver international : official journal of the International Association for the Study of the Liver.
[94] Masahiko Kato,et al. Effects of oral branched-chain amino acid granules on event-free survival in patients with liver cirrhosis. , 2005, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.
[95] R. Gish,et al. Hepatic encephalopathy is associated with significantly increased mortality among patients awaiting liver transplantation , 2014, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.
[96] R. Butterworth,et al. Alterations of [3H]8-OH-DPAT and [3H]ketanserin binding sites in autopsied brain tissue from cirrhotic patients with hepatic encephalopathy , 1994, Neuroscience Letters.
[97] R. Adams,et al. THE ACQUIRED (NON-WILSONIAN) TYPE OF CHRONIC HEPATOCEREBRAL DEGENERATION , 1965, Medicine.
[98] A. Read,et al. Lactobacillus acidophilus (Enpac) in Treatment of Hepatic Encephalopathy , 1966, British medical journal.
[99] A. McCullough,et al. Late evening snack: Exploiting a period of anabolic opportunity in cirrhosis , 2012, Journal of gastroenterology and hepatology.
[100] P. Amodio,et al. Neurocognitive-neurological complications of liver transplantation: a review , 2010, Metabolic Brain Disease.
[101] M. Ferraz,et al. A critical analysis of studies assessing L-ornithine-L-aspartate (LOLA) in hepatic encephalopathy treatment. , 2009, Arquivos de gastroenterologia.
[102] F. Moeller,et al. Liver transplantation significantly improves global functioning and cerebral processing , 2016, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.
[103] F. Marotta,et al. Endotoxinemia and benzodiazepine-like substances in compensated cirrhotic patients: a randomized study comparing the effect of rifaximine alone and in association with a symbiotic preparation. , 2004, Hepatology research : the official journal of the Japan Society of Hepatology.
[104] F. X. Aymerich,et al. A Long-Term Study of Changes in the Volume of Brain Ventricles and White Matter Lesions After Successful Liver Transplantation , 2010, Transplantation.
[105] M. Holeček. Three targets of branched-chain amino acid supplementation in the treatment of liver disease. , 2010, Nutrition.
[106] R. Gish,et al. Sodium benzoate for treatment of hepatic encephalopathy. , 2013, Gastroenterology & hepatology.
[107] M. Morgan,et al. Bromocriptine-associated hyponatraemia in cirrhosis. , 1982, British medical journal.
[108] J. Chalk,et al. Improvement in chronic hepatocerebral degeneration following liver transplantation. , 1990, Gastroenterology.
[109] D. Larkman,et al. Current and future applications of magnetic resonance imaging and spectroscopy of the brain in hepatic encephalopathy. , 2006, World journal of gastroenterology.
[110] J. Córdoba,et al. Hyponatremic and hepatic encephalopathies: similarities, differences and coexistence , 2010, Metabolic Brain Disease.
[111] J. Daurès,et al. Lactitol or lactulose in the treatment of chronic hepatic encephalopathy: Results of a meta‐analysis , 1992, Hepatology.
[112] N. Pavese,et al. Brain metabolism in patients with hepatic encephalopathy studied by PET and MR. , 2013, Archives of biochemistry and biophysics.
[113] N. Bass. Review article: the current pharmacological therapies for hepatic encephalopathy , 2007, Alimentary pharmacology & therapeutics.
[114] R. Butterworth,et al. L-Ornithine-L-Aspartate in Experimental Portal-Systemic Encephalopathy: Therapeutic Efficacy and Mechanism of Action , 1998, Metabolic Brain Disease.
[115] M. Uribe,et al. Acidifying enemas (lactitol and lactose) vs. nonacidifying enemas (tap water) to treat acute portal‐systemic encephalopathy: A double‐blind, randomized clinical trial , 1987, Hepatology.
[116] M. Morgan,et al. Letter: stepwise diagnosis in covert hepatic encephalopathy – critical flicker frequency and MELD‐score as a first‐step approach. Replication and pitfalls , 2017, Alimentary pharmacology & therapeutics.
[117] T E Starzl,et al. Nonalcoholic cirrhosis associated with neuropsychological dysfunction in the absence of overt evidence of hepatic encephalopathy. , 1984, Gastroenterology.
[118] D. Häussinger,et al. Hepatic encephalopathy: clinical aspects and pathogenetic concept. , 2013, Archives of biochemistry and biophysics.
[119] M. Hashizume,et al. Laparoscopic disconnection of a huge paraumbilical vein shunt for portosystemic encephalopathy. , 2007, Surgical laparoscopy, endoscopy & percutaneous techniques.
[120] R. Butterworth,et al. Increased Density of Catalytic Sites and Expression of Brain Monoamine Oxidase A in Humans with Hepatic Encephalopathy , 1997, Journal of neurochemistry.
[121] Karin Weissenborn,et al. The treatment of hepatic encephalopathy , 2007, Metabolic Brain Disease.
[122] E. Kass,et al. TREATMENT OF HEPATIC ENCEPHALOPATHY BY ALTERATION OF INTESTINAL FLORA WITH LACTOBACILLUS ACIDOPHILUS. , 1965, Lancet.
[123] N. Klöcker,et al. Synaptic plasticity in hepatic encephalopathy - a molecular perspective. , 2013, Archives of biochemistry and biophysics.
[124] Reversible periodic alternating gaze deviation in hepatic encephalopathy , 1995, Neurology.
[125] J Hennig,et al. Proton magnetic resonance spectroscopy studies on human brain myo-inositol in hypo-osmolarity and hepatic encephalopathy. , 1994, Gastroenterology.
[126] A. Saad,et al. METABOLIC STUDIES WITH THE DIURETIC TRIAMTERENE IN PATIENTS WITH CIRRHOSIS AND ASCITES. , 1964, The New England journal of medicine.
[127] Antonio Gasbarrini,et al. Extracorporeal albumin dialysis with the molecular adsorbent recirculating system in acute‐on‐chronic liver failure: The RELIEF trial , 2013, Hepatology.
[128] Hans Schomerus,et al. Quality of Life in Cirrhotics with Minimal Hepatic Encephalopathy , 2001, Metabolic Brain Disease.
[129] Wei Zheng,et al. Relationship Between Changes in Brain MRI and 1H-MRS, Severity of Chronic Liver Damage, and Recovery After Liver Transplantation , 2009, Experimental biology and medicine.
[130] B. Sharma,et al. Predictors of nonresponse to lactulose in patients with cirrhosis and hepatic encephalopathy , 2010, European journal of gastroenterology & hepatology.
[131] K. Takeda,et al. Improvement of regional cerebral blood flow after oral intake of branched-chain amino acids in patients with cirrhosis. , 2005, World journal of gastroenterology.
[132] D. Rockey,et al. Randomized, double-blind, controlled study of glycerol phenylbutyrate in hepatic encephalopathy , 2014, Hepatology.
[133] D. Skene,et al. Night‐time sleep disturbance does not correlate with neuropsychiatric impairment in patients with cirrhosis , 2009, Liver international : official journal of the International Association for the Study of the Liver.
[134] A. Tomasello,et al. Successful Embolization of a Spontaneous Mesocaval Shunt Using the Amplatzer Vascular Plug II , 2010, CardioVascular and Interventional Radiology.
[135] W. Sibbitt,et al. Proton MR spectroscopic measurement of neurometabolites in hepatic encephalopathy during oral lactulose therapy. , 1998, AJNR. American journal of neuroradiology.
[136] Tabershaw Ir,et al. Benzene and leukaemia. , 1977 .
[137] D. Einstadter,et al. A New Look at Precipitants of Overt Hepatic Encephalopathy in Cirrhosis , 2017, Digestive Diseases and Sciences.
[138] C. Zauner,et al. Partial pressure of ammonia versus ammonia in hepatic encephalopathy , 2000, Hepatology.
[139] S. Schiff,et al. Electroencephalographic staging of hepatic encephalopathy by an artificial neural network and an expert system 1 , 2005, Neurophysiologie Clinique/Clinical Neurophysiology.
[140] D. Shawcross,et al. Inflammation and hepatic encephalopathy. , 2013, Archives of biochemistry and biophysics.
[141] N.J. Shah,et al. Quantitative cerebral water content mapping in hepatic encephalopathy , 2008, NeuroImage.
[142] Brendan McGuire,et al. Randomized controlled study of extracorporeal albumin dialysis for hepatic encephalopathy in advanced cirrhosis , 2007, Hepatology.
[143] D. Rockey,et al. Hepatic Encephalopathy: Pharmacological Therapies Targeting Ammonia , 2016, Seminars in Liver Disease.
[144] L. Seeff,et al. Comparison of lactulose and neomycin in the treatment of chronic portal-systemic encephalopathy. A double blind controlled trial. , 1977, Gastroenterology.
[145] M. Vergara,et al. Treatment of hepatic encephalopathy , 1997, The Lancet.
[146] P. Kaplan. The EEG in Metabolic Encephalopathy and Coma , 2004, Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society.
[147] R. Buchert,et al. Radiotracer imaging studies in hepatic encephalopathy: ISHEN practice guidelines , 2009, Liver international : official journal of the International Association for the Study of the Liver.
[148] M. Mcphail,et al. Meta-analysis: the diagnostic accuracy of critical flicker frequency in minimal hepatic encephalopathy , 2013, Alimentary pharmacology & therapeutics.
[149] S. Hori,et al. Portal-systemic encephalopathy: presence of basal ganglia lesions with high signal intensity on MR images. , 1991, Radiology.
[150] K. Weissenborn,et al. Bradykinesia in minimal hepatic encephalopathy is due to disturbances in movement initiation. , 2003, Journal of hepatology.
[151] M. Morgan,et al. Flumazenil versus placebo or no intervention for people with cirrhosis and hepatic encephalopathy. , 2017, The Cochrane database of systematic reviews.
[152] R. Butterworth,et al. Manganese deposition in basal ganglia structures results from both portal-systemic shunting and liver dysfunction. , 1999, Gastroenterology.
[153] H. Hodkinson. Evaluation of a mental test score for assessment of mental impairment in the elderly. , 1972, Age and ageing.
[154] K Weissenborn,et al. Neuropsychological characterization of hepatic encephalopathy. , 2001, Journal of hepatology.
[155] R. Jalan,et al. Reversal of diuretic-induced hepatic encephalopathy with infusion of albumin but not colloid. , 2004, Clinical science.
[156] J. Hennig,et al. Proton magnetic resonance spectroscopy of the brain in symptomatic and asymptomatic patients with liver cirrhosis. , 1997, Gastroenterology.
[157] V. Felipo,et al. Oral administration of sildenafil restores learning ability in rats with hyperammonemia and with portacaval shunts , 2005, Hepatology.
[158] J. A. Arranz,et al. Impact of ornithine phenylacetate (OCR-002) in lowering plasma ammonia after upper gastrointestinal bleeding in cirrhotic patients , 2016, Therapeutic advances in gastroenterology.
[159] Y. Joshi,et al. Auditory P300 event‐related potentials and number connection test for evaluation of subclinical hepatic encephalopathy in patients with cirrhosis of the liver: A follow‐up study , 2001, Journal of gastroenterology and hepatology.
[160] M. Plauth,et al. ESPEN Guidelines on Enteral Nutrition: Liver disease. , 2006, Clinical nutrition.
[161] A. Schnitzler,et al. Neurophysiological investigations of hepatic encephalopathy: ISHEN practice guidelines , 2009, Liver international : official journal of the International Association for the Study of the Liver.
[162] M. Dam,et al. 18F-fluorodeoxyglucose positron emission tomography study of brain metabolism in cirrhosis: effect of liver transplantation. , 1999, Transplantation proceedings.
[163] M. Morgan,et al. Lactitol and lactulose for the treatment of subclinical hepatic encephalopathy in cirrhotic patients. A randomised, cross-over study. , 1989, Journal of hepatology.
[164] A. Lockwood,et al. Hepatic encephalopathy—Definition, nomenclature, diagnosis, and quantification: Final report of the Working Party at the 11th World Congresses of Gastroenterology, Vienna, 1998 , 2002, Hepatology.
[165] J. Vinel,et al. Pre‐transjugular intrahepatic portosystemic shunts (TIPS) prediction of post‐TIPS overt hepatic encephalopathy: The Critical Flicker Frequency is more accurate than psychometric tests , 2014, Hepatology.
[166] H Schomerus,et al. Latent portasystemic encephalopathy , 1981, Digestive Diseases and Sciences.
[167] Sara Montagnese,et al. Disruption of smooth pursuit eye movements in cirrhosis: Relationship to hepatic encephalopathy and its treatment , 2005, Hepatology.
[168] U. de Girolami,et al. Neuropathology of liver transplantation. , 1995, Clinical neuropathology.
[169] R. Butterworth,et al. Neurobiology of ammonia , 2002, Progress in Neurobiology.
[170] J. Lai,et al. Brain α‐Ketoglutarate Dehydrogenase Complex: Kinetic Properties, Regional Distribution, and Effects of Inhibitors , 1986, Journal of neurochemistry.
[171] J. Bircher,et al. mechanism of the excessive sedative response of cirrhotics to benzodiazepines: Model experiments with triazolam , 1987, Hepatology.
[172] Y. Inoue,et al. Leucine stimulates the secretion of hepatocyte growth factor by hepatic stellate cells. , 2002, Biochemical and biophysical research communications.
[173] K. Saeian,et al. Testing for minimal hepatic encephalopathy in the United States: An AASLD survey , 2007, Hepatology.
[174] R. Esteban,et al. Normal protein diet for episodic hepatic encephalopathy: results of a randomized study. , 2004, Journal of hepatology.
[175] P. Angeli,et al. Prevalence and prognostic value of quantified electroencephalogram (EEG) alterations in cirrhotic patients. , 2001, Journal of hepatology.
[176] M. Morgan,et al. Characteristics of Minimal Hepatic Encephalopathy , 2004, Metabolic Brain Disease.
[177] C. Zwingmann,et al. Effects of ammonia on high affinity glutamate uptake and glutamate transporter EAAT3 expression in cultured rat cerebellar granule cells , 2003, Neurochemistry International.
[178] A. Farcomeni,et al. Hepatic encephalopathy expands the predictivity of model for end‐stage liver disease in liver transplant setting: Evidence by means of 2 independent cohorts , 2016, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.
[179] L. Caregaro,et al. Study on the Sternberg Paradigm in Cirrhotic Patients Without Overt Hepatic Encephalopathy , 1998, Metabolic Brain Disease.
[180] B. Sharma,et al. An open-label randomized controlled trial of lactulose and probiotics in the treatment of minimal hepatic encephalopathy , 2008, European journal of gastroenterology & hepatology.
[181] Manuel Romero-Gómez,et al. Minimal hepatic encephalopathy and critical flicker frequency are associated with survival of patients with cirrhosis. , 2015, Gastroenterology.
[182] A. Drewes,et al. New spectral thresholds improve the utility of the electroencephalogram for the diagnosis of hepatic encephalopathy , 2016, Clinical Neurophysiology.
[183] J. Cummings,et al. Nitrogen in fecal bacterial, fiber, and soluble fractions of patients with cirrhosis: effects of lactulose and lactulose plus neomycin. , 1987, The Journal of laboratory and clinical medicine.
[184] M. Navasa,et al. Prognostic significance of hepatic encephalopathy in patients with cirrhosis. , 1999, Journal of hepatology.
[185] S. Kulkarni,et al. Use of model for end‐stage liver disease exception points for early liver transplantation and successful reversal of hepatic myelopathy with a review of the literature , 2010, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.
[186] W. Hop,et al. Subclinical hepatic encephalopathy impairs daily functioning , 1998, Hepatology.
[187] M. Vlieger,et al. Objective measurement of hepatic encephalopathy by means of automated EEG analysis. , 1984, Electroencephalography and clinical neurophysiology.
[188] R. Dempsey,et al. GeneChip® analysis shows altered mRNA expression of transcripts of neurotransmitter and signal transduction pathways in the cerebral cortex of portacaval shunted rats , 2002, Journal of neuroscience research.
[189] P. Angeli,et al. Cognitive impairment and electroencephalographic alterations before and after liver transplantation: What is reversible? , 2014, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.
[190] R. Groszmann,et al. Long‐term hemodynamic effects of ketanserin, a 5‐hydroxytryptamine blocker, in portal hypertensive patients , 1989, Hepatology.
[191] G. D’Amico,et al. Natural history and prognostic indicators of survival in cirrhosis: a systematic review of 118 studies. , 2006, Journal of hepatology.
[192] Simpson Ma. A mythology of medical education. , 1974 .
[193] C. Loguercio,et al. Long-term effects of Enterococcus faecium SF68 versus lactulose in the treatment of patients with cirrhosis and grade 1-2 hepatic encephalopathy. , 1995, Journal of hepatology.
[194] J. Raskind,et al. The Role of Carnitine Supplementation during Valproic Acid Therapy , 2000, The Annals of pharmacotherapy.
[195] D. Krieger,et al. Neuropsychiatric profile and hyperintense globus pallidus on T1-weighted magnetic resonance images in liver cirrhosis. , 1996, Gastroenterology.
[196] Thomas A Hammeke,et al. Inhibitory control test for the diagnosis of minimal hepatic encephalopathy. , 2008, Gastroenterology.
[197] R. Dhiman,et al. Prevalence and natural history of subclinical hepatic encephalopathy in cirrhosis , 2001, Journal of gastroenterology and hepatology.
[198] G. D’Amico,et al. Survival and prognostic indicators in compensated and decompensated cirrhosis , 1986, Digestive Diseases and Sciences.
[199] M. Merli,et al. Effect of lactitol and lactulose administration on the fecal flora in cirrhotic patients. , 1990, Journal of clinical gastroenterology.
[200] R. Cunha,et al. Neuroprotection by adenosine in the brain: From A1 receptor activation to A2A receptor blockade , 2005, Purinergic Signalling.
[201] B. Gómez-Anson,et al. Hyponatremia Is a Risk Factor of Hepatic Encephalopathy in Patients With Cirrhosis: A Prospective Study With Time-Dependent Analysis , 2009, The American Journal of Gastroenterology.
[202] D. Fan,et al. Predictors of hepatic encephalopathy after transjugular intrahepatic portosystemic shunt in cirrhotic patients: A systematic review , 2011, Journal of gastroenterology and hepatology.
[203] M. Morgan,et al. Nonabsorbable disaccharides for hepatic encephalopathy: A systematic review and meta‐analysis , 2016, Hepatology.
[204] F. Poordad,et al. Review article: the burden of hepatic encephalopathy , 2007, Alimentary pharmacology & therapeutics.
[205] J. Villeneuve,et al. Surgical treatment of severe postshunt hepatic encephalopathy , 2005, World Journal of Surgery.
[206] E. Björnsson,et al. Renal function and cognitive impairment in patients with liver cirrhosis , 2007, Scandinavian journal of gastroenterology.
[207] H. Schomerus,et al. Neuropsychological Aspects of Portal-Systemic Encephalopathy , 1998, Metabolic Brain Disease.
[208] B. Lössner,et al. Correlations between zinc, amino acids and ammonia in liver cirrhosis. , 1989, Zeitschrift fur Gastroenterologie.
[209] J. Kondrup,et al. Long-term oral refeeding of patients with cirrhosis of the liver , 1995, British Journal of Nutrition.
[210] O. Riggio,et al. Emerging drugs for hepatic encephalopathy , 2009, Expert opinion on emerging drugs.
[211] Norbert Hilger,et al. Hepatic encephalopathy and fitness to drive. , 2009, Gastroenterology.
[212] Carlos Guarner,et al. Minimal Hepatic Encephalopathy Is Associated With Falls , 2011, The American Journal of Gastroenterology.
[213] C. Randolph,et al. Impact of preoperative overt hepatic encephalopathy on neurocognitive function after liver transplantation , 2009, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.
[214] K. Weissenborn. Challenges in Diagnosing Hepatic Encephalopathy , 2014, Neurochemical Research.
[215] D. Häussinger,et al. Gene expression profiling in the cerebral cortex of patients with cirrhosis with and without hepatic encephalopathy , 2013, Hepatology.
[216] C. Randolph,et al. Neuropsychological assessment of hepatic encephalopathy: ISHEN practice guidelines , 2009, Liver international : official journal of the International Association for the Study of the Liver.
[217] R. Kerlan,et al. Techniques for Transjugular Intrahepatic Portosystemic Shunt Reduction and Occlusion. , 2016, Techniques in vascular and interventional radiology.
[218] D. Aprile,et al. A low‐cost, user‐friendly electroencephalographic recording system for the assessment of hepatic encephalopathy , 2016, Hepatology.
[219] N. Chu,et al. Evoked potentials in liver diseases , 1997, Journal of gastroenterology and hepatology.
[220] A. Stracciari,et al. Minimal hepatic encephalopathy: longitudinal effects of liver transplantation. , 2004, Archives of neurology.
[221] J. Kulisevsky,et al. Magnetic resonance imaging pallidal hypersignal in cirrhotic subjects , 1996, Hepatology.
[222] M. Romero-Gómez,et al. Intestinal glutaminase activity is increased in liver cirrhosis and correlates with minimal hepatic encephalopathy. , 2004, Journal of hepatology.
[223] The kidney plays a major role in the hyperammonemia seen after simulated or actual GI bleeding in patients with cirrhosis , 2003, Hepatology.
[224] W. Kim,et al. Hepatic encephalopathy as a predictor of survival in patients with end‐stage liver disease , 2007, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.
[225] E. S. May,et al. The slowed brain: cortical oscillatory activity in hepatic encephalopathy. , 2013, Archives of biochemistry and biophysics.
[226] F. Schliess,et al. Pathogenetic mechanisms of hepatic encephalopathy , 2008, Gut.
[227] Andres F Carrion,et al. Endovascular Management of Refractory Hepatic Encephalopathy Complication of Transjugular Intrahepatic Portosystemic Shunt (TIPS): Comprehensive Review and Clinical Practice Algorithm , 2016, CardioVascular and Interventional Radiology.
[228] F. Galvano,et al. Bifidobacterium combined with fructo-oligosaccharide versus lactulose in the treatment of patients with hepatic encephalopathy , 2010, European journal of gastroenterology & hepatology.
[229] K. Weissenborn,et al. Qualifying and quantifying minimal hepatic encephalopathy , 2016, Metabolic Brain Disease.
[230] F. Weber. Lactulose and combination therapy of hepatic encephalopathy: the role of the intestinal microflora. , 1996, Digestive diseases.
[231] Khader M Hasan,et al. Demonstration of interstitial cerebral edema with diffusion tensor MR imaging in type C hepatic encephalopathy , 2006, Hepatology.
[232] D. Rockey,et al. Lactulose vs polyethylene glycol 3350--electrolyte solution for treatment of overt hepatic encephalopathy: the HELP randomized clinical trial. , 2014, JAMA internal medicine.
[233] M. Morgan,et al. Therapeutic studies in hepatic encephalopathy , 2007, Metabolic Brain Disease.
[234] H. Sørensen,et al. Clinical course of alcoholic liver cirrhosis: A Danish population‐based cohort study , 2010, Hepatology.
[235] P. Andersen,et al. Diabetes as a risk factor for hepatic encephalopathy in cirrhosis patients. , 2015, Journal of hepatology.
[236] M. Norenberg,et al. Ammonia downregulates GLAST mRNA glutamate transporter in rat astrocyte cultures , 1999, Neuroscience Letters.
[237] Jimmy D Bell,et al. Cerebral Phosphorus‐31 magnetic resonance spectroscopy in patients with chronic hepatic encephalopathy , 1994, Hepatology.
[238] M. Merli,et al. Peripheral and Splanchnic Indole and Oxindole Levels in Cirrhotic Patients: A Study on the Pathophysiology of Hepatic Encephalopathy , 2010, The American Journal of Gastroenterology.
[239] À. Rovira,et al. The development of low-grade cerebral edema in cirrhosis is supported by the evolution of (1)H-magnetic resonance abnormalities after liver transplantation. , 2001, Journal of hepatology.
[240] M. Norenberg,et al. Combined Effects of Ammonia and Manganese on Astrocytes in Culture , 2004, Neurochemical Research.
[241] Ching-Po Lin,et al. Reestablishing Brain Networks in Patients without Overt Hepatic Encephalopathy after Liver Transplantation , 2014, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[242] P. Angeli,et al. Hyponatremia in cirrhosis: Results of a patient population survey , 2006, Hepatology.
[243] R. Butterworth,et al. Monoamines and metabolites in autopsied brain tissue from cirrhotic patients with hepatic encephalopathy , 1989, Neurochemical Research.
[244] A. Burroughs,et al. Embolization of large spontaneous portosystemic shunts for refractory hepatic encephalopathy: A multicenter survey on safety and efficacy , 2013, Hepatology.
[245] A. Sanyal,et al. Predictors of the recurrence of hepatic encephalopathy in lactulose‐treated patients , 2010, Alimentary pharmacology & therapeutics.
[246] Y. Dagon,et al. Cannabinoids ameliorate cerebral dysfunction following liver failure via AMP‐activated protein kinase , 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[247] G. Marchesini,et al. Nutritional supplementation with branched-chain amino acids in advanced cirrhosis: a double-blind, randomized trial. , 2003, Gastroenterology.
[248] E. Tolosa,et al. Hyperintense globus pallidus on T1‐weighted MRI in cirrhotic patients is associated with severity of liver failure , 1993, Neurology.
[249] Praveen Sharma,et al. Critical flicker frequency for diagnosis and assessment of recovery from minimal hepatic encephalopathy in patients with cirrhosis. , 2010, Hepatobiliary & pancreatic diseases international : HBPD INT.
[250] P. Hayes,et al. Psychological outcome and quality of life following liver transplantation: A prospective, national, single‐center study , 2003, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.
[251] J. Vincent,et al. Severe sepsis in cirrhosis , 2009, Hepatology.
[252] R. Butterworth. Neurosteroids in hepatic encephalopathy: Novel insights and new therapeutic opportunities , 2016, The Journal of Steroid Biochemistry and Molecular Biology.
[253] T. Reynolds,et al. Cerebrospinal fluid glutamine as a measure of hepatic encephalopathy. , 1971, Archives of internal medicine.
[254] P. Hayes,et al. Interorgan ammonia and amino acid metabolism in metabolically stable patients with cirrhosis and a TIPSS , 2002, Hepatology.