Microfiltration results in the loss of analytes and affects the in vitro genotoxicity of a complex mixture of Alternaria toxins

[1]  B. Warth,et al.  Gut microbiota and undigested food constituents modify toxin composition and suppress the genotoxicity of a naturally occurring mixture of Alternaria toxins in vitro , 2020, Archives of Toxicology.

[2]  G. Del Favero,et al.  Mycotoxin Altertoxin II Induces Lipid Peroxidation Connecting Mitochondrial Stress Response to NF-κB Inhibition in THP-1 Macrophages , 2020, Chemical research in toxicology.

[3]  B. Warth,et al.  First determination of the highly genotoxic fungal contaminant altertoxin II in a naturally infested apple sample , 2020 .

[4]  B. Warth,et al.  Bioavailability, metabolism, and excretion of a complex Alternaria culture extract versus altertoxin II: a comparative study in rats , 2019, Archives of Toxicology.

[5]  B. Warth,et al.  Naturally occurring mixtures of Alternaria toxins: anti-estrogenic and genotoxic effects in vitro , 2019, Archives of Toxicology.

[6]  L. Szente,et al.  Interactions of Mycotoxin Alternariol with Cyclodextrins and Its Removal from Aqueous Solution by Beta-Cyclodextrin Bead Polymer , 2019, Biomolecules.

[7]  B. Warth,et al.  Quantitation of free and modified Alternaria mycotoxins in European food products by LC-MS/MS , 2019, Food Control.

[8]  M. Rychlik,et al.  Quantitation of Six Alternaria Toxins in Infant Foods Applying Stable Isotope Labeled Standards , 2019, Front. Microbiol..

[9]  G. Del Favero,et al.  First insights into Alternaria multi-toxin in vivo metabolism. , 2019, Toxicology letters.

[10]  B. Shao,et al.  Determination of Alternaria Mycotoxins in Fresh Sweet Cherries and Cherry-Based Products: Method Validation and Occurrence. , 2018, Journal of agricultural and food chemistry.

[11]  D. Marko,et al.  The mycotoxin alternariol suppresses lipopolysaccharide-induced inflammation in THP-1 derived macrophages targeting the NF-κB signalling pathway , 2018, Archives of Toxicology.

[12]  D. Marko,et al.  The mycotoxin alternariol suppresses lipopolysaccharide-induced inflammation in THP-1 derived macrophages targeting the NF-κB signalling pathway , 2018, Archives of Toxicology.

[13]  Michael Rychlik,et al.  Chemotaxonomy of Mycotoxigenic Small-Spored Alternaria Fungi – Do Multitoxin Mixtures Act as an Indicator for Species Differentiation? , 2018, Front. Microbiol..

[14]  A. Tritscher,et al.  Mycotoxin contamination of sorghum and its contribution to human dietary exposure in four sub-Saharan countries , 2018, Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.

[15]  Doris Marko,et al.  Tracking emerging mycotoxins in food: development of an LC-MS/MS method for free and modified Alternaria toxins , 2018, Analytical and Bioanalytical Chemistry.

[16]  G. Del Favero,et al.  An integrated in silico/in vitro approach to assess the xenoestrogenic potential of Alternaria mycotoxins and metabolites. , 2018, Food chemistry.

[17]  F. Masino,et al.  Determination of four Alternaria alternata mycotoxins by QuEChERS approach coupled with liquid chromatography-tandem mass spectrometry in tomato-based and fruit-based products. , 2018, Food research international.

[18]  B. Warth,et al.  Delphinidin protects colon carcinoma cells against the genotoxic effects of the mycotoxin altertoxin II. , 2018, Toxicology letters.

[19]  L. Radko,et al.  Nonsteroidal mycotoxin alternariol is a full androgen agonist in the yeast reporter androgen bioassay. , 2017, Environmental toxicology and pharmacology.

[20]  F. Berthiller,et al.  Emerging Mycotoxins: Beyond Traditionally Determined Food Contaminants. , 2017, Journal of agricultural and food chemistry.

[21]  S. Croubels,et al.  Emerging Fusarium and Alternaria Mycotoxins: Occurrence, Toxicity and Toxicokinetics , 2017, Toxins.

[22]  J. Beisl,et al.  Genistein and delphinidin antagonize the genotoxic effects of the mycotoxin alternariol in human colon carcinoma cells , 2017, Molecular nutrition & food research.

[23]  D. Arcella,et al.  Dietary exposure assessment to Alternaria toxins in the European population , 2016 .

[24]  C. Juan,et al.  Development and Validation of a LC-ESI-MS/MS Method for the Determination of Alternaria Toxins Alternariol, Alternariol Methyl-Ether and Tentoxin in Tomato and Tomato-Based Products , 2016, Toxins.

[25]  G. Del Favero,et al.  Dual effectiveness of Alternaria but not Fusarium mycotoxins against human topoisomerase II and bacterial gyrase , 2016, Archives of Toxicology.

[26]  B. Warth,et al.  Synergistic estrogenic effects of Fusarium and Alternaria mycotoxins in vitro , 2016, Archives of Toxicology.

[27]  L. Jacxsens,et al.  Validated UPLC-MS/MS Methods To Quantitate Free and Conjugated Alternaria Toxins in Commercially Available Tomato Products and Fruit and Vegetable Juices in Belgium. , 2016, Journal of Agricultural and Food Chemistry.

[28]  M. Metzler,et al.  DNA damage and repair kinetics of the Alternaria mycotoxins alternariol, altertoxin II and stemphyltoxin III in cultured cells. , 2016, Mutation research. Genetic toxicology and environmental mutagenesis.

[29]  H. Mol,et al.  Occurrence of Alternaria toxins in food products in The Netherlands , 2016 .

[30]  C. Juan,et al.  Rapid Quantification Method of Three Alternaria Mycotoxins in Strawberries , 2016, Food Analytical Methods.

[31]  H. Humpf,et al.  Survey of Alternaria toxin contamination in food from the German market, using a rapid HPLC-MS/MS approach , 2016, Mycotoxin Research.

[32]  A. Solhaug,et al.  The mycotoxin alternariol induces DNA damage and modify macrophage phenotype and inflammatory responses. , 2015, Toxicology letters.

[33]  J. Stroka,et al.  Simultaneous analysis of Alternaria toxins and citrinin in tomato: an optimised method using liquid chromatography-tandem mass spectrometry , 2015, Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.

[34]  A. Torbica,et al.  Alternaria toxins in wheat from the Autonomous Province of Vojvodina, Serbia: a preliminary survey , 2015, Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.

[35]  B. Shao,et al.  Natural occurrence of four Alternaria mycotoxins in tomato- and citrus-based foods in China. , 2015, Journal of agricultural and food chemistry.

[36]  T. Hansen,et al.  Combined toxicokinetic and in vivo genotoxicity study on Alternaria toxins , 2014 .

[37]  G. Cano-Sancho,et al.  Mycotoxins: occurrence, toxicology, and exposure assessment. , 2013, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[38]  M. Gullino,et al.  A new method for detection of five alternaria toxins in food matrices based on LC-APCI-MS. , 2013, Food chemistry.

[39]  E. Ropstad,et al.  An in vitro investigation of endocrine disrupting effects of the mycotoxin alternariol. , 2013, Toxicology and applied pharmacology.

[40]  G. Pahlke,et al.  Role of topoisomerase inhibition and DNA repair mechanisms in the genotoxicity of alternariol and altertoxin-II , 2013 .

[41]  Rudolf Krska,et al.  LC-MS/MS-based multibiomarker approaches for the assessment of human exposure to mycotoxins , 2013, Analytical and Bioanalytical Chemistry.

[42]  D. Marko,et al.  Characterization of a genotoxic impact compound in Alternaria alternata infested rice as Altertoxin II , 2012, Archives of Toxicology.

[43]  D. Marko,et al.  Minor contribution of alternariol, alternariol monomethyl ether and tenuazonic acid to the genotoxic properties of extracts from Alternaria alternata infested rice. , 2012, Toxicology letters.

[44]  M. Metzler,et al.  Alternaria toxins: Altertoxin II is a much stronger mutagen and DNA strand breaking mycotoxin than alternariol and its methyl ether in cultured mammalian cells. , 2012, Toxicology letters.

[45]  Josep Rubert,et al.  Analysis of mycotoxins in barley using ultra high liquid chromatography high resolution mass spectrometry: comparison of efficiency and efficacy of different extraction procedures. , 2012, Talanta.

[46]  Martin Rother,et al.  Determination of six Alternaria toxins with UPLC-MS/MS and their occurrence in tomatoes and tomato products from the Swiss market , 2011, Mycotoxin Research.

[47]  M. Koch,et al.  Degradation of the Alternaria mycotoxins alternariol, alternariol monomethyl ether, and altenuene upon bread baking. , 2010, Journal of agricultural and food chemistry.

[48]  Yves-Jacques Schneider,et al.  LC-MS/MS multi-analyte method for mycotoxin determination in food supplements , 2009, Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.

[49]  Morten O. Christensen,et al.  Alternariol acts as a topoisomerase poison, preferentially affecting the IIalpha isoform. , 2009, Molecular nutrition & food research.

[50]  V. Ostry,et al.  Alternaria mycotoxins: an overview of chemical characterization, producers, toxicity, analysis and occurrence in foodstuffs , 2008 .

[51]  M. Metzler,et al.  Estrogenic and clastogenic potential of the mycotoxin alternariol in cultured mammalian cells. , 2006, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[52]  M. Carlson,et al.  Analyte loss due to membrane filter adsorption as determined by high-performance liquid chromatography. , 2000, Journal of chromatographic science.

[53]  R. Tice,et al.  Single cell gel/comet assay: Guidelines for in vitro and in vivo genetic toxicology testing , 2000, Environmental and molecular mutagenesis.