Early detection of cancerous tissues in human breast utilizing near field microwave holography

This work demonstrates an application of near field indirect microwave holography for the detection of malignant tissues in human breast in an effective way. The holograms are recorded by two directive antennas aligned along each other's boresight while performing a raster scan over a 2D plane utilizing XY‐linear motorized translation stage and a uniform reference wave. The whole information that is, amplitude and phase of an object has been provided by indirect holography at microwave frequencies. The extracted phase values are used to determine the dielectric permittivity values which are further utilized for the identification and validating the positions of malignant tissues in the breast phantom. The experimental evaluations performed on the in‐house designed and developed tissue mimicking 3D printed breast phantoms. The experimental results demonstrate the ability of microwave holography using directive antennas in detecting and identifying the tumors upto the minimum size of 4 mm and maximum depth of 25 mm in fabricated phantom. The quantitative results present the potential of the Near Field Indirect Holographic Imaging (NFIHI) in order to develop an efficient and economical tool for breast cancer detection.

[1]  A. M. Nicolson,et al.  Measurement of the Intrinsic Properties of Materials by Time-Domain Techniques , 1970 .

[2]  W. Weir.  Automatic measurement of complex dielectric constant and permeability at microwave frequencies , 1974 .

[3]  Mehrdad Soumekh.  Bistatic synthetic aperture radar inversion with application in dynamic object imaging , 1991, IEEE Trans. Signal Process..

[4]  Thomas E. Hall,et al.  Three-dimensional millimeter-wave imaging for concealed weapon detection , 2001 .

[5]  Paul M. Meaney,et al.  Microwaves for breast cancer detection , 2003 .

[6]  V. Schejbal,et al.  Accuracy Analyses of Synthesized-Reference-Wave Holography for Determining Antenna Radiation Characteristics , 2008, IEEE Antennas and Propagation Magazine.

[7]  Lulu Wang,et al.  3D breast cancer imaging using holographic microwave interferometry , 2012, IVCNZ '12.

[8]  Ahmed M. Al-Jumaily,et al.  Holographic microwave imaging for medical applications , 2013 .

[9]  Stephen Pistorius,et al.  Holographic reconstruction of multistatic breast microwave radar images: Initial results on synthetic phantoms , 2013, 2013 International Conference on Electromagnetics in Advanced Applications (ICEAA).

[10]  O. Yurduseven,et al.  EARLY STAGE BREAST CANCER DETECTION USING INDIRECT MICROWAVE HOLOGRAPHY , 2013 .

[11]  Sima Noghanian,et al.  Study of Penetration Depth and Noise in Microwave Tomography Technique , 2013 .

[12]  T. A. Rahman,et al.  Investigation on dielectric properties in gelatin-based phantom for human brain , 2014, 2014 International Symposium on Antennas and Propagation Conference Proceedings.

[13]  Hu Peng,et al.  Holographic Microwave Imaging for Breast Cancer Detection Based on Compressive Sensing , 2017 .

[14]  Ritesh Vyas,et al.  Development and analysis of anatomically real breast phantoms using different dispersion models , 2018, J. Electronic Imaging.

[15]  G. Sheoran,et al.  Development of Microstrip Patch Antenna for Indirect Microwave Holographic System , 2018, 2018 IEEE MTT-S International Microwave and RF Conference (IMaRC).

[16]  Martin O’Halloran,et al.  Microwave Breast Imaging: Clinical Advances and Remaining Challenges , 2018, IEEE Transactions on Biomedical Engineering.

[17]  Tirupathiraju Kanumuri,et al.  SAR analysis of directive antenna on anatomically real breast phantoms for microwave holography , 2019, Microwave and Optical Technology Letters.

[18]  Chandra Shakher,et al.  Experimental Investigation of Directive Antenna in Near Field Indirect Microwave Holography , 2019 .

[19]  Indirect microwave holography with resolution enhancement in metallic imaging , 2019, International Journal of RF and Microwave Computer-Aided Engineering.