BEBaC user manual
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BEBaC [1] (Bayesian estimation of bacterial communities) is a software devoting to estimate bacterial communities from large amounts of deep sequencing data of 16S rRNA gene. A dataset which contains 4K~100K reads of length 400bp~2000bp is suitable for BEBaC. Larger datasets are also possible, but we have not tested on these datasets. Here “reads” means DNA sequences produced by a sequencing machine.
[1] Robert C. Edgar,et al. MUSCLE: multiple sequence alignment with high accuracy and high throughput. , 2004, Nucleic acids research.
[2] Jukka Corander,et al. Bayesian estimation of bacterial community composition from 454 sequencing data , 2012, Nucleic acids research.
[3] Jukka Corander,et al. Bayesian analysis of population structure based on linked molecular information. , 2007, Mathematical biosciences.