A method for the alignment of heterogeneous macromolecules from electron microscopy.

[1]  上田 良二.  Electron microscopy 1966 , 1966 .

[2]  M. Heel,et al.  Exact filters for general geometry three dimensional reconstruction , 1986 .

[3]  George C. Stockman,et al.  Object recognition and localization via pose clustering , 1987, Comput. Vis. Graph. Image Process..

[4]  J. Frank,et al.  Three‐dimensional reconstruction from a single‐exposure, random conical tilt series applied to the 50S ribosomal subunit of Escherichia coli , 1987, Journal of microscopy.

[5]  M. Heel,et al.  Angular reconstitution: a posteriori assignment of projection directions for 3D reconstruction. , 1987 .

[6]  Marin van Heel,et al.  Classification of image data in conjugate representation spaces , 1990 .

[7]  T. Steitz,et al.  Crystal structures of the Klenow fragment of DNA polymerase I complexed with deoxynucleoside triphosphate and pyrophosphate. , 1993, Biochemistry.

[8]  Clark F. Olson.  Time and space efficient pose clustering , 1994, 1994 Proceedings of IEEE Conference on Computer Vision and Pattern Recognition.

[9]  J. Frank,et al.  The ribosome at improved resolution: new techniques for merging and orientation refinement in 3D cryo-electron microscopy of biological particles. , 1994, Ultramicroscopy.

[10]  J. Frank,et al.  A common-lines based method for determining orientations for N > 3 particle projections simultaneously. , 1996, Ultramicroscopy.

[11]  Guy Marchal,et al.  Multi-modality image registration by maximization of mutual information , 1996, Proceedings of the Workshop on Mathematical Methods in Biomedical Image Analysis.

[12]  Guy Marchal,et al.  Multimodality image registration by maximization of mutual information , 1997, IEEE Transactions on Medical Imaging.

[13]  C. Guthrie,et al.  Mechanical Devices of the Spliceosome: Motors, Clocks, Springs, and Things , 1998, Cell.

[14]  M van Heel,et al.  The Escherichia coli large ribosomal subunit at 7.5 A resolution. , 1999, Structure.

[15]  W. Chiu,et al.  Three-dimensional structure of low density lipoproteins by electron cryomicroscopy. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[16]  J. Frank,et al.  Solution Structure of the E. coli 70S Ribosome at 11.5 Å Resolution , 2000, Cell.

[17]  M. Heel,et al.  Single-particle electron cryo-microscopy: towards atomic resolution , 2000, Quarterly Reviews of Biophysics.

[18]  N Grigorieff,et al.  Resolution measurement in structures derived from single particles. , 2000, Acta crystallographica. Section D, Biological crystallography.

[19]  H. Saibil,et al.  Allostery and protein substrate conformational change during GroEL/GroES-mediated protein folding. , 2001, Advances in protein chemistry.

[20]  B. Gowen,et al.  Structures of unliganded and ATP-bound states of the Escherichia coli chaperonin GroEL by cryoelectron microscopy. , 2001, Journal of structural biology.

[21]  Joachim Frank,et al.  Cryo‐EM reveals an active role for aminoacyl‐tRNA in the accommodation process , 2002, The EMBO journal.

[22]  J. Frank.  Single-particle imaging of macromolecules by cryo-electron microscopy. , 2002, Annual review of biophysics and biomolecular structure.

[23]  E. Egelman,et al.  Flexibility of the rings: structural asymmetry in the DnaB hexameric helicase. , 2002, Journal of molecular biology.

[24]  Yang-Ming Zhu,et al.  Influence of implementation parameters on registration of MR and SPECT brain images by maximization of mutual information. , 2002, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[25]  Laurent Joyeux,et al.  Efficiency of 2D alignment methods. , 2002, Ultramicroscopy.

[26]  K. Henrick,et al.  New electron microscopy database and deposition system. , 2002, Trends in biochemical sciences.

[27]  Max A. Viergever,et al.  Mutual-information-based registration of medical images: a survey , 2003, IEEE Transactions on Medical Imaging.

[28]  J. Frank.  Toward an understanding of the structural basis of translation , 2003, Genome Biology.

[29]  S. Burgess,et al.  Use of negative stain and single-particle image processing to explore dynamic properties of flexible macromolecules. , 2004, Journal of structural biology.

[30]  Helen E White,et al.  Recognition and separation of single particles with size variation by statistical analysis of their images. , 2004, Journal of molecular biology.

[31]  Paul A. Viola,et al.  Alignment by Maximization of Mutual Information , 1997, International Journal of Computer Vision.

[32]  S. Wakil,et al.  Experimental verification of conformational variation of human fatty acid synthase as predicted by normal mode analysis. , 2004, Structure.

[33]  Bjoern Sander,et al.  Major conformational change in the complex SF3b upon integration into the spliceosomal U11/U12 di-snRNP as revealed by electron cryomicroscopy. , 2005, Molecular cell.

[34]  E. Nogales,et al.  Structural Roles for Human Translation Factor eIF3 in Initiation of Protein Synthesis , 2005, Science.

[35]  Florence Tama,et al.  The 13 angstroms structure of a chaperonin GroEL-protein substrate complex by cryo-electron microscopy. , 2005, Journal of molecular biology.

[36]  Charles L. Brooks,et al.  The 13 Å Structure of a Chaperonin GroEL–Protein Substrate Complex by Cryo-electron Microscopy , 2005 .

[37]  J. Frank,et al.  A method of focused classification, based on the bootstrap 3D variance analysis, and its application to EF-G-dependent translocation. , 2006, Journal of structural biology.

[38]  María J. Ledesma-Carbayo,et al.  Molecular image registration using mutual information and differential evolution optimization , 2006, 3rd IEEE International Symposium on Biomedical Imaging: Nano to Macro, 2006..

[39]  Chao Yang,et al.  Estimation of variance in single-particle reconstruction using the bootstrap technique. , 2006, Journal of structural biology.

[40]  G. Herman,et al.  Disentangling conformational states of macromolecules in 3D-EM through likelihood optimization , 2007, Nature Methods.

[41]  E. Nogales,et al.  Cross-correlation of common lines: a novel approach for single-particle reconstruction of a structure containing a flexible domain. , 2007, Journal of structural biology.

[42]  Andres E Leschziner,et al.  Visualizing flexibility at molecular resolution: analysis of heterogeneity in single-particle electron microscopy reconstructions. , 2007, Annual review of biophysics and biomolecular structure.

[43]  Jie Fu,et al.  Unsupervised classification of single particles by cluster tracking in multi-dimensional space. , 2007, Journal of structural biology.

[44]  E. Orlova,et al.  Detection and separation of heterogeneity in molecular complexes by statistical analysis of their two-dimensional projections. , 2008, Journal of structural biology.