Chewing-side Preference is Involved in Differential Cortical Activation Patterns during Tongue Movements after Bilateral Gum-chewing: a Functional Magnetic Resonance Imaging Study

Contralateral dominance in the activation of the primary sensorimotor cortex (S1/M1) during tongue movements (TMs) has been shown to be associated with a chewing-side preference (CSP). However, little is known about its interaction with chewing-related cortical activation. Functional magnetic resonance imaging was performed before and after gum-chewing in six subjects who exhibited a left CSP to determine the relationship between the CSP and activation patterns in the S1/M1 during TMs. Before the subjects chewed the gum, activation foci were found in the bilateral S1/M1. In the left hemisphere, both signal intensity and the area of activation significantly increased during TMs within 10 min after subjects chewed gum. Moreover, this augmented activation significantly decreased within 20 min during tongue protrusion and leftward movement. In the right hemisphere, there were no marked changes during TMs. These results suggest that bilateral gum-chewing enhances activation of the S1/M1 ipsilateral to the CSP during TMs.

[1]  R. C. Oldfield.  The assessment and analysis of handedness: the Edinburgh inventory. , 1971, Neuropsychologia.

[2]  M. Hallett,et al.  Rapid plasticity of human cortical movement representation induced by practice. , 1998, Journal of neurophysiology.

[3]  Y. Shinoda,et al.  Projection from area 3a to the motor cortex by neurons activated from group I muscle afferents , 1978, Experimental Brain Research.

[4]  J. Liepert,et al.  Motor plasticity induced by synchronized thumb and foot movements , 1999, Experimental Brain Research.

[5]  A A Lowe,et al.  Regulation of genioglossus and masseter muscle activity in man. , 1977, Archives of oral biology.

[6]  T. Kawasaki,et al.  Functional magnetic resonance imaging of human jaw movements. , 2003, Journal of oral rehabilitation.

[7]  Y Sasaki,et al.  Effect of mastication on regional cerebral blood flow in humans examined by positron-emission tomography with ¹⁵O-labelled water and magnetic resonance imaging. , 1997, Archives of oral biology.

[8]  K. Hiiemae,et al.  Tongue-jaw linkages in human feeding: a preliminary videofluorographic study. , 1997, Archives of oral biology.

[9]  Kinziro Kubota,et al.  Morphological studies of the neuromuscular mechanism shifting from sucking to biting of mice. , 1988, Acta anatomica.

[10]  M. Schieppati,et al.  Patterns of activity of perioral facial muscles during mastication in man , 2004, Experimental Brain Research.

[11]  E Honda,et al.  Hemispheric Dominance of Tongue Control Depends on the Chewing-side Preference , 2003, Journal of dental research.

[12]  Changes in regional cerebral blood flow during mastication in young and old normal subjects measured with positron emission tomography , 1992 .

[13]  M. Sesay,et al.  Assessment of regional cerebral blood flow by xenon-enhanced computed tomography during mastication in humans. , 2000, The Keio journal of medicine.

[14]  I. Adams,et al.  Comparison of synaptic changes in the precentral and postcentral cerebral cortex of aging humans: A quantitative ultrastructural study , 1987, Neurobiology of Aging.

[15]  T. Morimoto,et al.  Tongue, Jaw, and Lip Muscle Activity and Jaw Movement during Experimental Chewing Efforts in Man , 1996, Journal of dental research.

[16]  M. Onozuka,et al.  Mapping Brain Region Activity during Chewing: A Functional Magnetic Resonance Imaging Study , 2002, Journal of dental research.

[17]  K. Hiiemae,et al.  Tongue movements in feeding and speech. , 2003, Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists.

[18]  J. Donoghue.  Plasticity of adult sensorimotor representations , 1995, Current Opinion in Neurobiology.

[19]  M. Hector,et al.  The possible role of periodontal mechanoreceptors in the control of parotid secretion in man. , 1987, Quarterly journal of experimental physiology.

[20]  R W Cox,et al.  Event‐related fMRI of tasks involving brief motion , 1999, Human brain mapping.

[21]  G. Barnwell,et al.  Occlusion and chewing side preference. , 1986, The Journal of prosthetic dentistry.

[22]  K. Hiiemae,et al.  A postero-anterior videofluorographic study of the intra-oral management of food in man. , 2002, Archives of oral biology.

[23]  E. Seto,et al.  Quantifying Head Motion Associated with Motor Tasks Used in fMRI , 2001, NeuroImage.

[24]  M. Onozuka,et al.  Age-related Changes in Brain Regional Activity during Chewing: A Functional Magnetic Resonance Imaging Study , 2003, Journal of dental research.

[25]  K. Mauritz,et al.  Repetitive training of isolated movements improves the outcome of motor rehabilitation of the centrally paretic hand , 1995, Journal of the Neurological Sciences.

[26]  K. Ohkubo,et al.  Degenerative changes of primary neurons following tooth extraction. , 1988, Anatomischer Anzeiger.

[27]  B. Sessle,et al.  Effects on mastication of reversible bilateral inactivation of the lateral pericentral cortex in the monkey (Macaca fascicularis). , 2002, Archives of oral biology.

[28]  Reorganisation of the sensorimotor cortex after early focal brain lesion: a functional MRI study in monozygotic twins , 2001, Neuroreport.