A tool for collection of region based data from uterine cervix images for correlation of visual and clinical variables related to cervical neoplasia

The National Cancer Institute (NCI) is collaborating with the National Library of Medicine (NLM) to create a database of digitized images of the uterine cervix for research, training, and education. The database of 100,000 images collected in NCI projects will be Web-accessible and will contain not only the digitized images, but also clinical, longitudinal data relevant to the detection of uterine cervix cancer. The database will also contain spatial data in the form of expert-marked boundary regions of anatomy and tissue regions of high interest. The collection of this spatial data is enabled by customized software, the Boundary Marking Tool (BMT). The BMT, its significance, and its use in preliminary research studies, are described in this paper.

[1]  R. Reid,et al.  Genital warts and cervical cancer. VII. An improved colposcopic index for differentiating benign papillomaviral infections from high-grade cervical intraepithelial neoplasia. , 1985, American journal of obstetrics and gynecology.

[2]  L. Mango,et al.  Design and methods of a population-based natural history study of cervical neoplasia in a rural province of Costa Rica: the Guanacaste Project. , 1997, Revista panamericana de salud publica = Pan American journal of public health.

[3]  C J L M Meijer,et al.  The causal relation between human papillomavirus and cervical cancer. , 2002, Journal of clinical pathology.

[4]  Mark Schiffman,et al.  ASCUS-LSIL Triage Study , 2000, Acta Cytologica.

[5]  T. Wright,et al.  Cervical ectopy and the transformation zone measured by computerized planimetry in adolescents , 1999, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

[6]  A. Štafl,et al.  Cervicography: a new method for cervical cancer detection. , 1981, American journal of obstetrics and gynecology.

[7]  F. Bray,et al.  Cancer burden in the year 2000. The global picture. , 2001, European journal of cancer.

[8]  J. Eluf-Neto,et al.  Cervical cancer in Latin America. , 2001, Seminars in oncology.