Decoy receptor 3: a pleiotropic immunomodulator and biomarker for inflammatory diseases, autoimmune diseases and cancer.

[1]  S. Ladas,et al.  High intestinal and systemic levels of decoy receptor 3 (DcR3) and its ligand TL1A in active ulcerative colitis. , 2010, Clinical immunology.

[2]  Yen-Ling Wang,et al.  Decoy receptor 3 protects non-obese diabetic mice from autoimmune diabetes by regulating dendritic cell maturation and function. , 2010, Molecular immunology.

[3]  N. Manabe,et al.  Changes in the expression of decoy receptor 3 in granulosa cells during follicular atresia in porcine ovaries. , 2010, The Journal of reproduction and development.

[4]  Shu-Chun Lin,et al.  Serum decoy receptor 3 level: A predictive marker for nodal metastasis and survival among oral cavity cancer patients , 2010, Head and Neck.

[5]  Gang Xiong,et al.  Polymorphisms of decoy receptor 3 are associated with risk of esophageal squamous cell carcinoma in Chinese Han , 2010, Tumor Biology.

[6]  A. Zallone,et al.  The formation of osteoclasts in multiple myeloma bone disease patients involves the secretion of soluble decoy receptor 3 , 2010, Annals of the New York Academy of Sciences.

[7]  J. Bayry.  Immunology: TL1A in the inflammatory network in autoimmune diseases , 2010, Nature Reviews Rheumatology.

[8]  B. Han,et al.  DcR3 Protects Islet β Cells from Apoptosis through Modulating Adcyap1 and Bank1 Expression1 , 2009, The Journal of Immunology.

[9]  B. Aggarwal,et al.  Therapeutic Potential of VEGI/TL1A in Autoimmunity and Cancer. , 2009, Advances in experimental medicine and biology.

[10]  Chih-Chien Wang,et al.  Decoy receptor 3 ameliorates experimental autoimmune encephalomyelitis by directly counteracting local inflammation and downregulating Th17 cells. , 2009, Molecular immunology.

[11]  M. Kurosaka,et al.  DcR3 protects THP-1 macrophages from apoptosis by increasing integrin alpha4. , 2009, Biochemical and biophysical research communications.

[12]  T. Chou,et al.  Decoy receptor 3 levels in peripheral blood predict outcomes of acute respiratory distress syndrome. , 2009, American journal of respiratory and critical care medicine.

[13]  J. Fikes,et al.  Role of TL1A in the Pathogenesis of Rheumatoid Arthritis1 , 2009, The Journal of Immunology.

[14]  H. Grabsch,et al.  High resolution analysis of DNA copy-number aberrations of chromosomes 8, 13, and 20 in gastric cancers , 2009, Virchows Archiv.

[15]  Chi-Ju Chen,et al.  Decoy receptor 3, upregulated by Epstein-Barr virus latent membrane protein 1, enhances nasopharyngeal carcinoma cell migration and invasion. , 2009, Carcinogenesis.

[16]  P. Hytiroglou,et al.  Significance of increased expression of decoy receptor 3 in chronic liver disease. , 2009, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

[17]  C. Shun,et al.  Decoy receptor 3 expression during the menstrual cycle and pregnancy, and regulation by sex steroids in endometrial cells in vitro. , 2009, Human reproduction.

[18]  A. Mueller,et al.  The Decoy Receptor 3 (DcR3, TNFRSF6B) suppresses Th17 immune responses and is abundant in human cerebrospinal fluid , 2009, Journal of Neuroimmunology.

[19]  A. Strasser,et al.  The many roles of FAS receptor signaling in the immune system. , 2009, Immunity.

[20]  Pei-Hsuan Chen,et al.  Decoy Receptor 3 Expression in AsPC-1 Human Pancreatic Adenocarcinoma Cells via the Phosphatidylinositol 3-Kinase-, Akt-, and NF-κB-Dependent Pathway1 , 2008, The Journal of Immunology.

[21]  J. Andrieux,et al.  Fluorescence in situ hybridization characterization of ider(20q) in myelodysplastic syndrome , 2008, British journal of haematology.

[22]  P. Schirmacher,et al.  Functional characterisation of decoy receptor 3 in Crohn’s disease , 2008, Gut.

[23]  Gang Chen,et al.  Expression of decoy receptor 3 in liver tissue microarrays. , 2008, The National medical journal of India.

[24]  P. Sfikakis,et al.  Circulating levels of TNF-like cytokine 1A (TL1A) and its decoy receptor 3 (DcR3) in rheumatoid arthritis. , 2008, Clinical immunology.

[25]  J. Connor,et al.  Ascites from epithelial ovarian cancer contain high levels of functional decoy receptor 3 (DcR3) and is associated with platinum resistance. , 2008, Gynecologic oncology.

[26]  T. Ślebioda,et al.  The Death Receptor 3–TNF-like protein 1A pathway drives adverse bone pathology in inflammatory arthritis , 2008, The Journal of experimental medicine.

[27]  P. Schirmacher,et al.  Decoy receptor 3 is a prognostic factor in renal cell cancer. , 2008, Neoplasia.

[28]  Joseph T. Glessner,et al.  Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease , 2008, Nature Genetics.

[29]  S. Hsieh,et al.  Expression of a soluble decoy receptor 3 in patients with diffuse large B-cell lymphoma predicts clinical outcome. , 2008, International journal of oncology.

[30]  T. Ochi,et al.  LIGHT induces cell proliferation and inflammatory responses of rheumatoid arthritis synovial fibroblasts via lymphotoxin beta receptor. , 2008, Journal of Rheumatology.

[31]  C. Ware.  Targeting lymphocyte activation through the lymphotoxin and LIGHT pathways , 2008, Immunological Reviews.

[32]  S. Hsieh,et al.  Epigenetic control of MHC class II expression in tumor-associated macrophages by decoy receptor 3. , 2008, Blood.

[33]  T. Nakanishi,et al.  Molecular cloning and preliminary expression analysis of banded dogfish (Triakis scyllia) TNF decoy receptor 3 (TNFRSF6B). , 2008, Fish & shellfish immunology.

[34]  K. Muramoto,et al.  Isolation of epidermal cells and cDNA cloning of TNF decoy receptor 3 of conger eel, Conger myriaster. , 2008, Fish & shellfish immunology.

[35]  S. Hsieh,et al.  Elevated serum decoy receptor 3 with enhanced T cell activation in systemic lupus erythematosus , 2008, Clinical and experimental immunology.

[36]  S. Hsieh,et al.  Apoptosis of dendritic cells induced by decoy receptor 3 (DcR3). , 2008, Blood.

[37]  S. Hsieh,et al.  Decoy receptor 3 ameliorates an autoimmune crescentic glomerulonephritis model in mice. , 2007, Journal of the American Society of Nephrology : JASN.

[38]  yang-xin fu,et al.  The role of lymphotoxin receptor signaling in diseases. , 2007, Current molecular medicine.

[39]  R. Wolfert,et al.  Evaluation of the novel serum markers B7-H4, Spondin 2, and DcR3 for diagnosis and early detection of ovarian cancer. , 2007, Gynecologic oncology.

[40]  R. Gill,et al.  Differential cellular expression of LIGHT and its receptors in early gestation human placentas. , 2007, Journal of reproductive immunology.

[41]  G. Getz,et al.  Lymphotoxin ß Receptor–Dependent Control of Lipid Homeostasis , 2007, Science.

[42]  Chi-Ju Chen,et al.  Epstein-Barr Virus Transcription Activator Rta Upregulates Decoy Receptor 3 Expression by Binding to Its Promoter , 2007, Journal of Virology.

[43]  Wan-Wan Lin,et al.  Attenuation of Bone Mass and Increase of Osteoclast Formation in Decoy Receptor 3 Transgenic Mice* , 2007, Journal of Biological Chemistry.

[44]  T. Whiteside.  The Role of Death Receptor Ligands in Shaping Tumor Microenvironment , 2007, Immunological investigations.

[45]  A. Keshavarzian,et al.  Apoptosis resistance in ulcerative colitis: High expression of decoy receptors by lamina propria T cells , 2006, European journal of immunology.

[46]  F. Cominelli,et al.  Role of TL1A and its receptor DR3 in two models of chronic murine ileitis. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[47]  J. Ramírez,et al.  Fas activation of a proinflammatory program in rheumatoid synoviocytes and its regulation by FLIP and caspase 8 signaling. , 2006, Arthritis and rheumatism.

[48]  J. Edwards,et al.  LIGHT (TNFSF14), a novel mediator of bone resorption, is elevated in rheumatoid arthritis. , 2006, Arthritis and rheumatism.

[49]  M. Fukuzawa,et al.  Significant Inhibition of Human CD8+ Cytotoxic T Lymphocyte-Mediated Xenocytotoxicity by Overexpression of the Human Decoy Fas Antigen , 2006, Transplantation.

[50]  S. Hsieh,et al.  The Glycosaminoglycan-Binding Domain of Decoy Receptor 3 Is Essential for Induction of Monocyte Adhesion1 , 2006, The Journal of Immunology.

[51]  J. Ragoussis,et al.  Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease. , 2005, Human molecular genetics.

[52]  Yung-Chi Chang,et al.  Attenuation of Th1 Response in Decoy Receptor 3 Transgenic Mice1 , 2005, The Journal of Immunology.

[53]  Shun-liang Gao,et al.  Overexpression of decoy receptor 3 in hepatocellular carcinoma and its association with resistance to Fas ligand-mediated apoptosis. , 2005, World journal of gastroenterology.

[54]  P. di Sant'Agnese,et al.  Overexpression of decoy receptor 3 in precancerous lesions and adenocarcinoma of the esophagus. , 2005, American journal of clinical pathology.

[55]  K. Pfeffer,et al.  Contribution of the Lymphotoxin β Receptor to Liver Regeneration1 , 2005, The Journal of Immunology.

[56]  Sunghee Kim,et al.  Increased expression of soluble decoy receptor 3 in acutely inflamed intestinal epithelia. , 2005, Clinical immunology.

[57]  yang-xin fu,et al.  Tumor necrosis factor family members and inflammatory bowel disease , 2005, Immunological reviews.

[58]  O. Tachibana,et al.  Frequent gene amplification and overexpression of decoy receptor 3 in glioblastoma , 2005, Acta Neuropathologica.

[59]  Wan-Wan Lin,et al.  Decoy Receptor 3 Increases Monocyte Adhesion to Endothelial Cells via NF-κB-Dependent Up-Regulation of Intercellular Adhesion Molecule-1, VCAM-1, and IL-8 Expression1 , 2005, The Journal of Immunology.

[60]  S. Hsieh,et al.  Soluble decoy receptor 3: increased levels in atopic patients. , 2004, The Journal of allergy and clinical immunology.

[61]  S. Hsieh,et al.  Transgenic Expression of Decoy Receptor 3 Protects Islets from Spontaneous and Chemical-induced Autoimmune Destruction in Nonobese Diabetic Mice , 2004, The Journal of experimental medicine.

[62]  Chi-Hung Lin,et al.  Modulation of macrophage differentiation and activation by decoy receptor 3 , 2004, Journal of leukocyte biology.

[63]  Wan-Wan Lin,et al.  Decoy receptor 3 (DcR3) induces osteoclast formation from monocyte/macrophage lineage precursor cells , 2004, Cell Death and Differentiation.

[64]  Wan-Wan Lin,et al.  Soluble Decoy Receptor 3 Induces Angiogenesis by Neutralization of TL1A, a Cytokine Belonging to Tumor Necrosis Factor Superfamily and Exhibiting Angiostatic Action , 2004, Cancer Research.

[65]  Sunghee Kim,et al.  Quantification and detection of DcR3, a decoy receptor in TNFR family. , 2004, Journal of immunological methods.

[66]  H. Juan,et al.  Immunomodulatory effect of decoy receptor 3 on the differentiation and function of bone marrow‐derived dendritic cells in nonobese diabetic mice: from regulatory mechanism to clinical implication , 2004, Journal of leukocyte biology.

[67]  A. Chiu,et al.  Enhanced adhesion of monocytes via reverse signaling triggered by decoy receptor 3. , 2004, Experimental cell research.

[68]  P. Moore,et al.  Selective Induction of Tumor Necrosis Receptor Factor 6/Decoy Receptor 3 Release by Bacterial Antigens in Human Monocytes and Myeloid Dendritic Cells , 2004, Infection and Immunity.

[69]  M. Imamura,et al.  Endogenous decoy receptor 3 blocks the growth inhibition signals mediated by Fas ligand in human pancreatic adenocarcinoma , 2003, International journal of cancer.

[70]  J. Bridgham,et al.  Characterization of chicken TNFR superfamily decoy receptors, DcR3 and osteoprotegerin. , 2003, Biochemical and biophysical research communications.

[71]  P. Moore,et al.  Clinical significance of detecting elevated serum DcR3/TR6/M68 in malignant tumor patients , 2003, International journal of cancer.

[72]  M. Peter,et al.  The CD95 type I/type II model. , 2003, Seminars in immunology.

[73]  Ming-Jing Hwang,et al.  The Role of Apoptosis Signal-regulating Kinase 1 in Lymphotoxin-β Receptor-mediated Cell Death* , 2003, The Journal of Biological Chemistry.

[74]  D. Witcher,et al.  Pharmacokinetics, metabolic stability, and subcutaneous bioavailability of a genetically engineered analog of DcR3, FLINT [DcR3(R218Q)], in cynomolgus monkeys and mice. , 2003, Drug metabolism and disposition: the biological fate of chemicals.

[75]  R. Herrmann,et al.  DCR3 locus is a predictive marker for 5‐fluorouracil‐based adjuvant chemotherapy in colorectal cancer , 2002, International journal of cancer.

[76]  Y. Nakajima,et al.  The prognostic significance of overexpression of the decoy receptor for Fas ligand (DcR3) in patients with gastric carcinomas , 2002, Gastric Cancer.

[77]  A. Chiu,et al.  Modulation of Dendritic Cell Differentiation and Maturation by Decoy Receptor 31 , 2002, The Journal of Immunology.

[78]  Hongguang Pan,et al.  A novel secreted splice variant of vascular endothelial cell growth inhibitor , 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[79]  Jun Zhang,et al.  TL1A is a TNF-like ligand for DR3 and TR6/DcR3 and functions as a T cell costimulator. , 2002, Immunity.

[80]  Yoon Lee,et al.  Tumor Necrosis Factor Receptor Superfamily 14 Is Involved in Atherogenesis by Inducing Proinflammatory Cytokines and Matrix Metalloproteinases , 2001, Arteriosclerosis, thrombosis, and vascular biology.

[81]  Yun Hee Cho,et al.  In vivo inhibition of Fas ligand-mediated killing by TR6, a Fas ligand decoy receptor. , 2001, The Journal of pharmacology and experimental therapeutics.

[82]  J. Ringel,et al.  Pancreatic Adenocarcinoma Cell Lines Show Variable Susceptibility to TRAIL-Mediated Cell Death , 2001, Pancreas.

[83]  V. Tron,et al.  Ultraviolet Light (UV) Regulation of the TNF Family Decoy Receptors DcR2 and DcR3 in Human Keratinocytes , 2001 .

[84]  H Chen,et al.  Modulation of T-cell responses to alloantigens by TR6/DcR3. , 2001, The Journal of clinical investigation.

[85]  M. Weller,et al.  Soluble decoy receptor 3 is expressed by malignant gliomas and suppresses CD95 ligand-induced apoptosis and chemotaxis. , 2001, Cancer research.

[86]  K. Ohshima,et al.  Amplification and expression of a decoy receptor for fas ligand (DcR3) in virus (EBV or HTLV-I) associated lymphomas. , 2000, Cancer letters.

[87]  G. Zhu,et al.  Modulation of T-cell-mediated immunity in tumor and graft-versus-host disease models through the LIGHT co-stimulatory pathway , 2000, Nature Medicine.

[88]  Otsuki,et al.  Over‐expression of the decoy receptor 3 (DcR3) gene in peripheral blood mononuclear cells (PBMC) derived from silicosis patients , 2000, Clinical and experimental immunology.

[89]  J. Bobe,et al.  A Tumor Necrosis Factor Decoy Receptor Homologue Is Up-Regulated in the Brook Trout (Salvelinus fontinalis) Ovary at the Completion of Ovulation1 , 2000, Biology of reproduction.

[90]  M. Metzker,et al.  Overexpression of M68/DcR3 in human gastrointestinal tract tumors independent of gene amplification and its location in a four-gene cluster. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[91]  S. Nagata,et al.  Essential roles of the Fas-Fas ligand pathway in the development of pulmonary fibrosis. , 1999, The Journal of clinical investigation.

[92]  Jian Ni,et al.  A Newly Identified Member of Tumor Necrosis Factor Receptor Superfamily (TR6) Suppresses LIGHT-mediated Apoptosis* , 1999, The Journal of Biological Chemistry.

[93]  D. Botstein,et al.  Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer , 1998, Nature.

[94]  D. Green.  Apoptosis: Death deceiver , 1998, Nature.

[95]  S. Nagata,et al.  Essential roles of the Fas ligand in the development of hepatitis , 1997, Nature Medicine.

[96]  C. Ware,et al.  A lymphotoxin-beta-specific receptor. , 1994, Science.

[97]  C. Ware.  Targeting the LIGHT-HVEM pathway. , 2009, Advances in experimental medicine and biology.

[98]  G. Getz,et al.  Lymphotoxin beta receptor-dependent control of lipid homeostasis. , 2007, Science.

[99]  K. Pfeffer,et al.  Contribution of the lymphotoxin beta receptor to liver regeneration. , 2005, Journal of immunology.

[100]  S. Hsieh,et al.  Sensitization of cells to TRAIL-induced apoptosis by decoy receptor 3. , 2004, Journal of Biological Chemistry.

[101]  B. Dixon,et al.  Cloning of a novel rainbow trout (Oncorhynchus mykiss) CC chemokine with a fractalkine-like stalk and a TNF decoy receptor using cDNA fragments containing AU-rich elements. , 2002, Cytokine.

[102]  C. Ware,et al.  LIGHT, a new member of the TNF superfamily, and lymphotoxin alpha are ligands for herpesvirus entry mediator. , 1998, Immunity.