In vitro metabolism of carbofuran by human, mouse, and rat cytochrome P450 and interactions with chlorpyrifos, testosterone, and estradiol.

[1]  E. Hodgson,et al.  In vitro metabolism of fipronil by human and rat cytochrome P450 and its interactions with testosterone and diazepam. , 2004, Chemico-biological interactions.

[2]  A. Conney,et al.  Characterization of the oxidative metabolites of 17beta-estradiol and estrone formed by 15 selectively expressed human cytochrome p450 isoforms. , 2003, Endocrinology.

[3]  E. Hodgson,et al.  Inhibition and activation of the human liver microsomal and human cytochrome P450 3A4 metabolism of testosterone by deployment-related chemicals. , 2003, Drug metabolism and disposition: the biological fate of chemicals.

[4]  T. Igarashi,et al.  Effects of endogenous steroids on CYP3A4-mediated drug metabolism by human liver microsomes. , 2002, Drug metabolism and disposition: the biological fate of chemicals.

[5]  J. Houston,et al.  Multisite kinetic models for CYP3A4: simultaneous activation and inhibition of diazepam and testosterone metabolism. , 2001, Drug metabolism and disposition: the biological fate of chemicals.

[6]  A. D. Rodrigues,et al.  Testosterone, 7-benzyloxyquinoline, and 7-benzyloxy-4-trifluoromethyl-coumarin bind to different domains within the active site of cytochrome P450 3A4. , 2001, Drug metabolism and disposition: the biological fate of chemicals.

[7]  K. Yaguchi,et al.  Toxicity and effects of 2,6-di-tert-butyl-4-methylphenyl N-methylcarbamate (terbutol) on hepatic cytochrome P450 in F344 rats , 2001, Archives of Toxicology.

[8]  A. Blair,et al.  Agricultural Exposure to Carbamate Pesticides and Risk of Non-Hodgkin Lymphoma , 2001, Journal of occupational and environmental medicine.

[9]  A. Y. Lu,et al.  Human cytochrome P-450 3A4: in vitro drug-drug interaction patterns are substrate-dependent. , 2000, Drug metabolism and disposition: the biological fate of chemicals.

[10]  Rodrigues Ad,et al.  Integrated Cytochrome P450 Reaction Phenotyping: Attempting to Bridge the Gap Between cDNA-expressed Cytochromes P450 and Native Human Liver Microsomes , 1999 .

[11]  A. D. Rodrigues,et al.  Integrated cytochrome P450 reaction phenotyping: attempting to bridge the gap between cDNA-expressed cytochromes P450 and native human liver microsomes. , 1999, Biochemical pharmacology.

[12]  J. Lehmann,et al.  The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions. , 1998, The Journal of clinical investigation.

[13]  J. Halpert,et al.  Analysis of human cytochrome P450 3A4 cooperativity: construction and characterization of a site-directed mutant that displays hyperbolic steroid hydroxylation kinetics. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[14]  T. Kost,et al.  CYP3A4 expressed by insect cells infected with a recombinant baculovirus containing both CYP3A4 and human NADPH-cytochrome P450 reductase is catalytically similar to human liver microsomal CYP3A4. , 1995, Archives of biochemistry and biophysics.

[15]  A. Conney,et al.  High-performance liquid chromatography separation of hydroxylated estradiol metabolites: formation of estradiol metabolites by liver microsomes from male and female rats. , 1995, The Journal of pharmacology and experimental therapeutics.

[16]  K. Korzekwa,et al.  Activation of CYP3A4: evidence for the simultaneous binding of two substrates in a cytochrome P450 active site. , 1994, Biochemistry.

[17]  R. Gupta,et al.  Carbofuran toxicity. , 1994, Journal of toxicology and environmental health.

[18]  D. Smith,et al.  Species differences in metabolism and pharmacokinetics: are we close to an understanding? , 1991, Drug metabolism reviews.

[19]  Fukuto Tr.  Mechanism of action of organophosphorus and carbamate insecticides. , 1990 .

[20]  T. R. Fukuto,et al.  Mechanism of action of organophosphorus and carbamate insecticides. , 1990, Environmental health perspectives.

[21]  T. Shimada,et al.  Evidence for cytochrome P-450NF, the nifedipine oxidase, being the principal enzyme involved in the bioactivation of aflatoxins in human liver. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[22]  E. Johnson,et al.  Modulation of rabbit and human hepatic cytochrome P-450-catalyzed steroid hydroxylations by alpha-naphthoflavone. , 1988, Molecular pharmacology.

[23]  E. Hodgson,et al.  Induction of cytochrome P-450 by methylenedioxyphenyl compounds: importance of the methylene carbon. , 1983, Toxicology and applied pharmacology.

[24]  J. Schenkman,et al.  Purification and characterization of two constitutive forms of rat liver microsomal cytochrome P-450. , 1982, The Journal of biological chemistry.

[25]  K. Ji,et al.  Postnatal endocrine dysfunction resulting from prenatal exposure to carbofuran, diazinon or chlordane. , 1978 .

[26]  Thomas Ja,et al.  Effects of pesticides on metabolism of steroid hormone by rodent liver microsomes. , 1978 .

[27]  J. I. Kitay,et al.  Postnatal endocrine dysfunction resulting from prenatal exposure to carbofuran, diazinon or chlordane. , 1978, Journal of environmental pathology and toxicology.

[28]  J. A. Thomas,et al.  Effects of pesticides on metabolism of steroid hormone by rodent liver microsomes. , 1978, Journal of environmental pathology and toxicology.