Biomolecular data : a resource in transition

Part 1 The emergence of biomolecular data management: data proliferation - a challenge for science and for CODATA, A.E.Busard how much sequence data the databanks will be processing in the near future, C.Burks CODATA helps the development of sequence databases, B.Keil the structure of nucleotide sequence databases, G.N.Cameron hte National Library of Medicine, D.A.B.Lindberg a method for the rapid and accurate deposition of nucleic acid data in an acceptably annotated form, R.T.Walker. Part 2 Managing biomolecular data: compilation of tRNA sequences and sequences of tRNA genes, M.Sprinzl problems in maintaining a protein sequence database, Y.Seto et al collection and standardization of crystal structure data by the protein data bank, T.F.Koetzle et al quality control for a rapidly changing database, W.C.Barker et al the database crisis - problems and solutions, efforts of an emerging Japanese database, A.Tsugita the human gene mapping library, R.L.Miller factual databases in basic research, R.J.Roberts the Berlin RNA database - problems and solutions, J.Wolters and V.Erdmann. Part 3 Using biochemical data: the problem with GENBANK, E.A.Kabat some perspective of a database user, R.M.Stephens why industrial scientists are interested in the future development of sequence databases, J.L.Modelevsky availability of nucleic acid sequences data in Poland, J.Augustyniack international protein and peptide database, B.Wittman-Liebold IRIS - integrated RNA information for systematics, H.Hori and Y.Saton expert system simulations as active learning environments, D.L.Brutlag integrated access to sequence and structural data - principles of design of comprehensive databases for molecular biology, A.Lesk searching for codes in the sequences, E.N.Trifonov semantic and syntactic patterns in the genetic language, T.F.Smith databases - what's there and what's needed, M.Kanehisa. Part 4 Future trends in the management of biomolecular data: toward global data interfacing, D.R.Masys linking sequence databases to the current scientific literature, D.A.Benson global interfacing of people, places, data and knowledge - calm seas and prosperous voyage?, M.I.Krichevsky global data exchange on compact disk read-only memory, F.R.Blattner BIONET - an NIH computer resource for molecular biology, D.L.Brutlag and D.Kristofferson the database as a communication medium, J.W.Fickett some ideas towards an electronic information centre for biotechnology, A.Fletcher computer education in biochemistry, chemistry and molecular biology, V.Erdmann et al sources of data in the GENBANK database, C.Burks to publish or not to publish DNA sequences, R.D.Wells to publish or not to publish, P.Kahn and L.Philipson.