Repetitive head impact exposure and later-life plasma total tau in former National Football League players

Blood protein analysis of total tau (t‐tau) may be a practical screening biomarker for chronic traumatic encephalopathy (CTE), a neurodegenerative tauopathy associated with repetitive head impact (RHI) exposure. We examined plasma t‐tau in symptomatic former National Football League (NFL) players compared with controls and the relationship between RHI exposure and later‐life plasma t‐tau.

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