Unbalanced whole-arm translocation der(18;21)(q10;q10) is a recurrent cytogenetic aberration appearing during progression in myeloid leukemias.
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[1] C. Fonatsch. The role of chromosome 21 in hematology and oncology , 2010, Genes, chromosomes & cancer.
[2] C. Harrison,et al. Intrachromosomal amplification of chromosome 21 (iAMP21) may arise from a breakage–fusion–bridge cycle , 2007, Genes, chromosomes & cancer.
[3] Sainan Wei,et al. Loss of 17p is a major consequence of whole-arm chromosome translocations in hematologic malignancies. , 2007, Cancer genetics and cytogenetics.
[4] T. Haferlach,et al. Gain of 9p due to an unbalanced rearrangement der(9;18): a recurrent clonal abnormality in chronic myeloproliferative disorders. , 2005, Cancer genetics and cytogenetics.
[5] H. Kantarjian,et al. Translocation t(17;18)(q10;q10) , 2001, Cancer.
[6] K. Thorling,et al. Many unbalanced translocations show duplication of a translocation participant. Clinical and cytogenetic implications in myeloid hematologic malignancies , 2000, American journal of hematology.
[7] N. Takahashi,et al. Fluorescence in situ hybridization of progenitor cells obtained by fluorescence-activated cell sorting for the detection of cells affected by chromosome abnormality trisomy 8 in patients with myelodysplastic syndromes. , 1998, Blood.
[8] A. Tobler,et al. Two clonal occurrences of tetrasomy 21 in an atypical chronic myeloid leukemia with wild-type RUNX1 alleles. Additional support for a gene dosage effect of chromosome 21 or RUNX1 in leukemia. , 2004, Haematologica.