Migraine and the trigeminovascular system—40 years and counting

[1]  G. Knudsen,et al.  Association Between Sumatriptan Treatment During a Migraine Attack and Central 5-HT1B Receptor Binding. , 2019, JAMA neurology.

[2]  M. Ashina The most important advances in headache research in 2018 , 2019, The Lancet Neurology.

[3]  R. Lipton,et al.  Lasmiditan is an effective acute treatment for migraine , 2018, Neurology.

[4]  Ivy Shiue,et al.  Global, regional, and national burden of migraine and tension-type headache, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016 , 2018, The Lancet Neurology.

[5]  M. Ashina,et al.  CGRP in Human Models of Migraine. , 2018, Handbook of experimental pharmacology.

[6]  M. Fishman,et al.  Fundamental science behind today’s important medicines , 2018, Science Translational Medicine.

[7]  M. Ashina,et al.  Targeted Pituitary Adenylate Cyclase-Activating Peptide Therapies for Migraine , 2018, Neurotherapeutics.

[8]  Mark B. Vestergaard,et al.  Heterogenous migraine aura symptoms correlate with visual cortex functional magnetic resonance imaging responses , 2017, Annals of neurology.

[9]  R. Burstein,et al.  Fremanezumab—A Humanized Monoclonal Anti-CGRP Antibody—Inhibits Thinly Myelinated (Aδ) But Not Unmyelinated (C) Meningeal Nociceptors , 2017, The Journal of Neuroscience.

[10]  J. Olesen,et al.  Human models of migraine — short-term pain for long-term gain , 2017, Nature Reviews Neurology.

[11]  M. Ashina,et al.  The KATP channel in migraine pathophysiology: a novel therapeutic target for migraine , 2017, The Journal of Headache and Pain.

[12]  P. Goadsby,et al.  Calcitonin gene-related peptide and pain: a systematic review , 2017, The Journal of Headache and Pain.

[13]  Hantao Liu,et al.  Immunohistochemical localization of the calcitonin gene-related peptide binding site in the primate trigeminovascular system using functional antagonist antibodies , 2016, Neuroscience.

[14]  Arne May,et al.  The migraine generator revisited: continuous scanning of the migraine cycle over 30 days and three spontaneous attacks. , 2016, Brain : a journal of neurology.

[15]  P. Goadsby,et al.  Neuronal PAC1 receptors mediate delayed activation and sensitization of trigeminocervical neurons: Relevance to migraine , 2015, Science Translational Medicine.

[16]  David Borsook,et al.  Migraine: Multiple Processes, Complex Pathophysiology , 2015, The Journal of Neuroscience.

[17]  Tsing-bau Chen,et al.  Localization of CGRP, CGRP receptor, PACAP and glutamate in trigeminal ganglion. Relation to the blood–brain barrier , 2015, Brain Research.

[18]  P. Goadsby,et al.  Pituitary adenylate cyclase activating polypeptide and migraine , 2014, Annals of clinical and translational neurology.

[19]  J. Olesen,et al.  Safety and efficacy of ALD403, an antibody to calcitonin gene-related peptide, for the prevention of frequent episodic migraine: a randomised, double-blind, placebo-controlled, exploratory phase 2 trial , 2014, The Lancet Neurology.

[20]  M. Brin,et al.  Selective inhibition of meningeal nociceptors by botulinum neurotoxin type A: Therapeutic implications for migraine and other pains , 2014, Cephalalgia : an international journal of headache.

[21]  H. Larsson,et al.  Magnetic resonance angiography of intracranial and extracranial arteries in patients with spontaneous migraine without aura: a cross-sectional study , 2013, The Lancet Neurology.

[22]  Z. Sen,et al.  Spreading Depression Triggers Headache by Activating Neuronal Panx1 Channels , 2013, Science.

[23]  Á. Párdutz,et al.  Peripheral and central alterations of pituitary adenylate cyclase activating polypeptide-like immunoreactivity in the rat in response to activation of the trigeminovascular system , 2012, Peptides.

[24]  David Borsook,et al.  Cortical Projections of Functionally Identified Thalamic Trigeminovascular Neurons: Implications for Migraine Headache and Its Associated Symptoms , 2011, The Journal of Neuroscience.

[25]  Dan Levy,et al.  Activation of central trigeminovascular neurons by cortical spreading depression , 2011, Annals of neurology.

[26]  J. Olesen,et al.  Evidence for a vascular factor in migraine , 2011, Annals of neurology.

[27]  A. May,et al.  Trigeminal Nociceptive Transmission in Migraineurs Predicts Migraine Attacks , 2011, The Journal of Neuroscience.

[28]  L. Becerra,et al.  Thalamic sensitization transforms localized pain into widespread allodynia , 2010, Annals of neurology.

[29]  Dan Levy,et al.  Activation of Meningeal Nociceptors by Cortical Spreading Depression: Implications for Migraine with Aura , 2010, The Journal of Neuroscience.

[30]  R. Burstein,et al.  Sensory innervation of the calvarial bones of the mouse , 2009, The Journal of comparative neurology.

[31]  J. Olesen,et al.  Origin of pain in migraine: evidence for peripheral sensitisation , 2009, The Lancet Neurology.

[32]  M. Ferrari,et al.  Migraine headache is not associated with cerebral or meningeal vasodilatation--a 3T magnetic resonance angiography study. , 2009, Brain : a journal of neurology.

[33]  S. Baker,et al.  Central pituitary adenylate cyclase 1 receptors modulate nociceptive behaviors in both inflammatory and neuropathic pain states. , 2008, The journal of pain : official journal of the American Pain Society.

[34]  R. Burstein,et al.  Mast cell degranulation activates a pain pathway underlying migraine headache , 2007, PAIN.

[35]  M. Moskowitz,et al.  Migraine as an inflammatory disorder , 2005, Neurology.

[36]  L. Edvinsson,et al.  Central projections of sensory innervation of the rat superior sagittal sinus , 2004, Neuroscience.

[37]  Karl J. Friston,et al.  A PET study exploring the laterality of brainstem activation in migraine using glyceryl trinitrate. , 2004, Brain : a journal of neurology.

[38]  J. Olesen,et al.  Calcitonin gene-related peptide receptor antagonist BIBN 4096 BS for the acute treatment of migraine. , 2004, The New England journal of medicine.

[39]  R. Burstein,et al.  Disruption of communication between peripheral and central trigeminovascular neurons mediates the antimigraine action of 5HT1B/1D receptor agonists , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[40]  Kirk W. Johnson,et al.  5-HT1F Receptor Agonists in Acute Migraine Treatment: A Hypothesis , 2003, Cephalalgia : an international journal of headache.

[41]  N. Dun,et al.  Modulation of nociceptive transmission by pituitary adenylate cyclase activating polypeptide in the spinal cord of the mouse , 2002, Pain.

[42]  J. Olesen,et al.  Cgrp May Play A Causative Role in Migraine , 2002, Cephalalgia : an international journal of headache.

[43]  Andrew K. Dunn,et al.  Intrinsic brain activity triggers trigeminal meningeal afferents in a migraine model , 2002, Nature Medicine.

[44]  M. Kanje,et al.  5-HT1B and 5-HT1D receptors in the human trigeminal ganglion: co-localization with calcitonin gene-related peptide, substance P and nitric oxide synthase , 2001, Brain Research.

[45]  B. Rosen,et al.  Mechanisms of migraine aura revealed by functional MRI in human visual cortex , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[46]  A. May,et al.  Substance P receptor antagonists in the therapy of migraine , 2001, Expert opinion on investigational drugs.

[47]  A. Bogers,et al.  Pharmacological analysis of contractile effects of eletriptan and sumatriptan on human isolated blood vessels. , 2000, European journal of pharmacology.

[48]  R. Burstein,et al.  Trigeminohypothalamic and reticulohypothalamic tract neurons in the upper cervical spinal cord and caudal medulla of the rat. , 2000, Journal of neurophysiology.

[49]  D. Yarnitsky,et al.  An association between migraine and cutaneous allodynia , 2000, Annals of neurology.

[50]  J. Narváez,et al.  Simultaneous depletion of neurokinin A, substance P and calcitonin gene-related peptide from the caudal trigeminal nucleus of the rat during electrical stimulation of the trigeminal ganglion , 2000, PAIN®.

[51]  M. Moskowitz,et al.  Both 5-HT1B and 5-HT1F receptors modulate c-fos expression within rat trigeminal nucleus caudalis. , 1999, European journal of pharmacology.

[52]  K. Messlinger,et al.  Release of substance P, calcitonin gene-related peptide and prostaglandin E2 from rat dura mater encephali following electrical and chemical stimulation in vitro , 1999, Neuroscience.

[53]  R. Burstein,et al.  Chemical stimulation of the intracranial dura induces enhanced responses to facial stimulation in brain stem trigeminal neurons. , 1998, Journal of neurophysiology.

[54]  Kirk W. Johnson,et al.  5‐HT1F receptor agonists inhibit neurogenic dural inflammation in guinea pigs , 1997, Neuroreport.

[55]  R. Burstein,et al.  Sensitization of meningeal sensory neurons and the origin of headaches , 1996, Nature.

[56]  D. Borsook,et al.  Distinct lateral and medial projections of the spinohypothalamic tract of the rat , 1996, The Journal of comparative neurology.

[57]  S. Boyce,et al.  Enantioselective inhibition of the formalin paw late phase by the NK1 receptor antagonist L-733,060 in gerbils , 1996, PAIN.

[58]  C. Weiller,et al.  Brain stem activation in spontaneous human migraine attacks , 1995, Nature Medicine.

[59]  H. Connor,et al.  The influence of the trigeminal ganglion on carotid blood flow in anaesthetized guinea‐pigs , 1994, British journal of pharmacology.

[60]  M. Lauritzen,et al.  Pathophysiology of the migraine aura. The spreading depression theory. , 1994, Brain : a journal of neurology.

[61]  P. Goadsby,et al.  The trigeminovascular system and migraine: Studies characterizing cerebrovascular and neuropeptide changes seen in humans and cats , 1993, Annals of neurology.

[62]  W. Carter,et al.  Dihydroergotamine and sumatriptan attenuate levels of CGRP in plasma in rat superior sagittal sinus during electrical stimulation of the trigeminal ganglion , 1991, Neuropharmacology.

[63]  M. G. Buzzi,et al.  The antimigraine drug, sumatriptan (GR43175), selectively blocks neurogenic plasma extravasation from blood vessels in dura mater , 1990, British journal of pharmacology.

[64]  A. Jamieson,et al.  The role of substance P and calcitonin gene-related peptide in neurogenic plasma extravasation and vasodilatation in the rat , 1989, Neuroscience.

[65]  M. Moskowitz,et al.  Indomethacin and acetylsalicylic acid block neurogenic plasma protein extravasation in rat dura mater. , 1989, European journal of pharmacology.

[66]  M. Moskowitz,et al.  Ergot alkaloids block neurogenic extravasation in dura mater: Proposed action in vascular headaches , 1988, Annals of neurology.

[67]  A. Doenicke,et al.  POSSIBLE BENEFIT OF GR43175, A NOVEL 5-HT1-LIKE RECEPTOR AGONIST, FOR THE ACUTE TREATMENT OF SEVERE MIGRAINE , 1988, The Lancet.

[68]  M. Moskowitz,et al.  Neurogenically Mediated Plasma Extravasation in Dura Mater: Effect of Ergot Alkaloids: A Possible Mechanism of Action in Vascular Headache , 1988, Cephalalgia : an international journal of headache.

[69]  P. Goadsby,et al.  Release of vasoactive peptides in the extracerebral circulation of humans and the cat during activation of the trigeminovascular system , 1988, Annals of neurology.

[70]  J. Dostrovsky,et al.  Responses of feline trigeminal spinal tract nucleus neurons to stimulation of the middle meningeal artery and sagittal sinus. , 1988, Journal of neurophysiology.

[71]  M. Moskowitz,et al.  Neurogenically mediated leakage of plasma protein occurs from blood vessels in dura mater but not brain , 1987, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[72]  J. Mcculloch,et al.  Innervation of the feline cerebral vasculature by nerve fibers containing calcitonin gene-related peptide: Trigeminal origin and co-existence with substance P , 1985, Neuroscience Letters.

[73]  J. Jollis,et al.  Innervation of the posterior fossa dura of the cat , 1985, Brain Research Bulletin.

[74]  M. Moskowitz The neurobiology of vascular head pain , 1984, Annals of neurology.

[75]  M. Moskowitz,et al.  Co‐localization of retrogradely transported wheat germ agglutinin and the putative neurotransmitter substance P within trigeminal ganglion cells projecting to cat middle cerebral artery , 1984, The Journal of comparative neurology.

[76]  P. Sawchenko,et al.  Release of the predicted calcitonin gene-related peptide from cultured rat trigeminal ganglion cells , 1984, Nature.

[77]  M. Moskowitz,et al.  Trigeminal projections to supratentorial pial and dural blood vessels in cats demonstrated by horseradish peroxidase histochemistry , 1984, The Journal of comparative neurology.

[78]  X. Hua,et al.  Vascular permeability changes and smooth muscle contraction in relation to capsaicin-sensitive substance P afferents in the guinea-pig. , 1984, Acta physiologica Scandinavica.

[79]  M. Moskowitz,et al.  In vitro release of immunoreactive substance P from putative afferent nerve endings in bovine pia arachnoid , 1983, Neuroscience.

[80]  M. Moskowitz,et al.  Pia arachnoid contains substance P originating from trigeminal neurons , 1983, Neuroscience.

[81]  M. Moskowitz,et al.  Immunohistochemical evidence for a substance P-containing trigeminovascular pathway to pial arteries in cats , 1983, Brain Research.

[82]  M. Moskowitz,et al.  Perivascular meningeal projections from cat trigeminal ganglia: possible pathway for vascular headaches in man. , 1981, Science.

[83]  J. Olesen,et al.  Focal hyperemia followed by spreading oligemia and impaired activation of rcbf in classic migraine , 1981, Annals of neurology.

[84]  E. Melamed,et al.  NEUROTRANSMITTERS AND THE FIFTH CRANIAL NERVE: IS THERE A RELATION TO THE HEADACHE PHASE OF MIGRAINE? , 1979, The Lancet.

[85]  M. Ashina,et al.  Meningeal contribution to migraine pain: a magnetic resonance angiography study , 2018, Brain : a journal of neurology.

[86]  D. Hay CGRP Receptor Biology: Is There More Than One Receptor? , 2018, Handbook of experimental pharmacology.

[87]  T. Sprenger,et al.  Brain activations in the premonitory phase of nitroglycerin-triggered migraine attacks. , 2014, Brain : a journal of neurology.

[88]  J. Olesen,et al.  PACAP38 induces migraine-like attacks in patients with migraine without aura. , 2009, Brain : a journal of neurology.

[89]  D. Duncker,et al.  Migraine headache is not associated with cerebral or meningeal vasodilatation--a 3T magnetic resonance angiography study. , 2009, Brain : a journal of neurology.

[90]  M. Kanje,et al.  5-HT(1B) and 5-HT(1D) receptors in the human trigeminal ganglion: co-localization with calcitonin gene-related peptide, substance P and nitric oxide synthase. , 2001, Brain research.

[91]  M. Moskowitz,et al.  Neurovascular and molecular mechanisms in migraine headaches. , 1993, Cerebrovascular and brain metabolism reviews.

[92]  M. Moskowitz Neurogenic versus vascular mechanisms of sumatriptan and ergot alkaloids in migraine. , 1992, Trends in pharmacological sciences.