Biocompatible and bioactive glass-ceramics — state of the art and new directions

Abstract This review describes biocompatible and bioactive glass-ceramics used as biomaterials for replacing bone structure in human medicine and restorative dentistry. The nucleation and crystallization mechanisms for both materials are presented, as well as the resulting microstructure of the glass-ceramics. In addition to the nucleation and crystallization processes, the properties, in particular those related to the solid state reactions resulting in bioactivity, will be examined. New directions in research and development are shown for the second material. Particular attention will be given to the solid-state reactions for the development of apatite—leucite glass-ceramics and glass-ceramics with a high ZrO 2 content for dental applications.

[1]  T. Kasuga,et al.  Preparation of High‐Strength Calcium Phosphate Ceramics with Low Modulus of Elasticity Containing β‐Ca(PO3)2 Fibers , 1996 .

[2]  W. J. O'brien,et al.  An outline of dental materials and their selection , 1978 .

[3]  G. Beall.  DESIGN AND PROPERTIES OF GLASS-CERAMICS , 1992 .

[4]  W. D. Kingery,et al.  Introduction to Ceramics , 1976 .

[5]  M. Frank,et al.  Surface crystallization of leucite in glasses , 1995 .

[6]  M. Tomozawa,et al.  Toughening of glass-ceramics by both transformable and transformed zirconia☆☆☆ , 1995 .

[7]  W. Höland,et al.  Control of phase formation processes in glass-ceramics for medicine and technology , 1991 .

[8]  T. Kasuga,et al.  Microstructure of Mica‐Based Nanocomposite Glass‐Ceramics , 1993 .

[9]  U. Gross,et al.  The anchoring of glass ceramics of different solubility in the femur of the rat. , 1980, Journal of biomedical materials research.

[10]  F. Pernot,et al.  Phosphate glass-ceramic-cobalt-chromium composite materials , 1992 .

[11]  Larry L. Hench,et al.  Bioceramics: From Concept to Clinic , 1991 .

[12]  M. I. Budd.  Sintering and crystallization of a glass powder in the MgO-Al2O3-SiO2-ZrO2 system , 1993, Journal of Materials Science.

[13]  Y. Abe.  Abnormal characteristics in crystallisation of Ca(PO3)2 glass , 1979, Nature.

[14]  R. Hill,et al.  Apatite-mullite glass-ceramics , 1996 .

[15]  W. Vogel,et al.  The Development of Bioglass Ceramics for Medical Applications , 1987 .

[16]  M. Tomozawa,et al.  Toughening mechanisms for a zirconia-lithium aluminosilicate glass-ceramic , 1995 .