Synthesis of esters and amides of 2-aryl-1-hydroxy-4-methyl-1H-imidazole-5-carboxylic acids and study of their antiviral activity against orthopoxviruses

[1]  D. C. Miguel,et al.  Antileishmanial and Anti‐Chikungunya Activity of Cu(I)‐N‐Heterocyclic Carbenes , 2022, ChemistrySelect.

[2]  N. Salakhutdinov,et al.  Synthesis and Antiviral Properties of Camphor-Derived Iminothiazolidine-4-Ones and 2,3-Dihydrothiazoles , 2022, Molecules.

[3]  Emily Harris What to Know About Monkeypox. , 2022, JAMA.

[4]  A. Abadi,et al.  Design and Synthesis of Novel Bis-Imidazolyl Phenyl Butadiyne Derivatives as HCV NS5A Inhibitors , 2022, Pharmaceuticals.

[5]  N. Minakawa,et al.  Synthesis and anti-dengue virus activity of 5-ethynylimidazole-4-carboxamide (EICA) nucleotide prodrugs. , 2021, Chemical & pharmaceutical bulletin.

[6]  Vasyl Kovalishyn,et al.  Design of new imidazole derivatives with anti-HCMV activity: QSAR modeling, synthesis and biological testing , 2021, Journal of Computer-Aided Molecular Design.

[7]  M. Bode,et al.  Studies towards the Design and Synthesis of Novel 1,5-Diaryl-1H-imidazole-4-carboxylic Acids and 1,5-Diaryl-1H-imidazole-4-carbohydrazides as Host LEDGF/p75 and HIV-1 Integrase Interaction Inhibitors , 2021, Molecules.

[8]  Yu Cao,et al.  Benefit-risk assessment for brincidofovir for the treatment of smallpox: U.S. Food and Drug Administration's Evaluation. , 2021, Antiviral research.

[9]  R. Maksyutov,et al.  Adamantane derivatives as potential inhibitors of p37 major envelope protein and poxvirus reproduction. Design, synthesis and antiviral activity , 2021, European journal of medicinal chemistry.

[10]  V. Zarubaev,et al.  Synthesis and Antiviral Activity of Camphene Derivatives against Different Types of Viruses , 2021, Molecules.

[11]  N. Salakhutdinov,et al.  (+)‐Camphor and (−)‐borneol derivatives as potential anti‐orthopoxvirus agents , 2021, Archiv der Pharmazie.

[12]  E. Kroon,et al.  Here, There, and Everywhere: The Wide Host Range and Geographic Distribution of Zoonotic Orthopoxviruses , 2020, Viruses.

[13]  R. Schinazi,et al.  Discovery and structure activity relationship of glyoxamide derivatives as anti-hepatitis B virus agents. , 2020, Bioorganic & medicinal chemistry.

[14]  A. Chernonosov,et al.  Estimation of Absolute Bioavailability of the Chemical Substance of the Anti-Smallpox Preparation NIOCH-14 in Mice , 2020, Bulletin of Experimental Biology and Medicine.

[15]  Andrew T. Russo,et al.  An overview of tecovirimat for smallpox treatment and expanded anti-orthopoxvirus applications , 2020, Expert review of anti-infective therapy.

[16]  N. Salakhutdinov,et al.  New chemical agents based on adamantane-monoterpene conjugates against orthopoxvirus infections. , 2020, RSC medicinal chemistry.

[17]  Y. Mitani,et al.  Optimization and biological evaluation of imidazopyridine derivatives as a novel scaffold for γ-secretase modulators with oral efficacy against cognitive deficits in Alzheimer's disease model mice. , 2020, Bioorganic & medicinal chemistry.

[18]  Gaoxue Wang,et al.  Synthesis and antiviral activity of a new arctigenin derivative against IHNV in vitro and in vivo. , 2019, Fish & shellfish immunology.

[19]  Gaoxue Wang,et al.  Synthesis and antiviral activity of coumarin derivatives against infectious hematopoietic necrosis virus. , 2019, Bioorganic & medicinal chemistry letters.

[20]  N. Minakawa,et al.  Synthesis and biological evaluation of novel imidazole nucleosides as potential anti-dengue virus agents. , 2019, Bioorganic & medicinal chemistry.

[21]  Chunjie Wang,et al.  Antiviral efficiency of a coumarin derivative on spring viremia of carp virus in vivo. , 2019, Virus research.

[22]  Gaoxue Wang,et al.  An imidazole coumarin derivative enhances the antiviral response to spring viremia of carp virus infection in zebrafish. , 2019, Virus research.

[23]  T. Schulz,et al.  Fragment-Based Discovery of a Qualified Hit Targeting the Latency-Associated Nuclear Antigen of the Oncogenic Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8. , 2019, Journal of medicinal chemistry.

[24]  A. Y. Tikhonov,et al.  Synthesis and antiviral activity of 1-hydroxy-2-(2-hydroxyphenyl)imidazoles against vaccinia virus , 2019, Russian Chemical Bulletin.

[25]  Gaoxue Wang,et al.  Synthesis of arctigenin derivatives against infectious hematopoietic necrosis virus. , 2019, European journal of medicinal chemistry.

[26]  S. Shchelkunov,et al.  [We should be prepared to smallpox re-emergence.] , 2019, Voprosy virusologii.

[27]  N. Salakhutdinov,et al.  Synthesis and antiviral activity of camphor-based 1,3-thiazolidin-4-one and thiazole derivatives as Orthopoxvirus-reproduction inhibitors. , 2018, MedChemComm.

[28]  S. Jang,et al.  Sulfur(vi) fluoride exchange as a key reaction for synthesizing biaryl sulfate core derivatives as potent hepatitis C virus NS5A inhibitors and their structure–activity relationship studies , 2018, RSC advances.

[29]  N. Salakhutdinov,et al.  Discovery of a New Class of Inhibitors of Vaccinia Virus Based on (−)‐Borneol from Abies sibirica and (+)‐Camphor , 2018, Chemistry & biodiversity.

[30]  M. S. Miftakhov,et al.  New 4H-thieno[3,2-b]pyrrole-5-carboxamides , 2018, Chemistry of Heterocyclic Compounds.

[31]  V. Perevalov,et al.  Methods of synthesis and physicochemical properties of 1-hydroxyimidazoles, imidazole 3-oxides, and their benzoannulated analogs , 2017, Chemistry of Heterocyclic Compounds.

[32]  Rebecca T. Ruck,et al.  Discovery of Ruzasvir (MK-8408): A Potent, Pan-Genotype HCV NS5A Inhibitor with Optimized Activity against Common Resistance-Associated Polymorphisms. , 2017, Journal of medicinal chemistry.

[33]  Seung Gi Lee,et al.  New potent biaryl sulfate-based hepatitis C virus inhibitors. , 2017, European journal of medicinal chemistry.

[34]  E. Asante-Appiah,et al.  Discovery of Chromane Containing Hepatitis C Virus (HCV) NS5A Inhibitors with Improved Potency against Resistance-Associated Variants. , 2016, Journal of medicinal chemistry.

[35]  A. A. Sergeev,et al.  New effective chemically synthesized anti-smallpox compound NIOCH-14. , 2016, The Journal of general virology.

[36]  J. Neyts,et al.  Synthesis and Structure-Activity Relationships of Imidazole-Coumarin Conjugates against Hepatitis C Virus , 2016, Molecules.

[37]  Zi-feng Yang,et al.  Imidazole-based pinanamine derivatives: Discovery of dual inhibitors of the wild-type and drug-resistant mutant of the influenza A virus. , 2016, European journal of medicinal chemistry.

[38]  Xu-li Tang,et al.  Imidazole Alkaloids from the South China Sea Sponge Pericharax heteroraphis and Their Cytotoxic and Antiviral Activities , 2016, Molecules.

[39]  Richard A. Stanton,et al.  Design, synthesis and evaluation of novel anti-HCV molecules that deliver intracellularly three highly potent NS5A inhibitors. , 2015, Bioorganic & medicinal chemistry letters.

[40]  Bo Chen,et al.  Design and synthesis of imidazole N-H substituted amide prodrugs as inhibitors of hepatitis C virus replication. , 2015, Bioorganic & medicinal chemistry letters.

[41]  J. Neyts,et al.  Design, synthesis and evaluation of a series of acyclic fleximer nucleoside analogues with anti-coronavirus activity , 2015, Bioorganic & Medicinal Chemistry Letters.

[42]  D. S. Shapiro The need for a decision: the future of biological science and humanity. , 2015, Future Microbiology.

[43]  C. Paddock,et al.  Poxvirus Viability and Signatures in Historical Relics , 2012, Emerging infectious diseases.

[44]  L. G. Kuz'mina,et al.  Synthesis and study of prototropic tautomerism of 2-(2-hydroxyphenyl)-1-hydroxyimidazoles , 2013 .

[45]  P. Balaresque,et al.  Variola virus in a 300-year-old Siberian mummy. , 2012, The New England journal of medicine.

[46]  P. Anderson,et al.  Bioterrorism: Pathogens as Weapons , 2012, Journal of pharmacy practice.

[47]  O. Chupakhin,et al.  Synthesis and antiviral activity of 1,2,4-triazine derivatives , 2012, Pharmaceutical Chemistry Journal.

[48]  K. M. Bormasheva,et al.  Synthesis and antiviral activity of new adamantane derivatives , 2012, Pharmaceutical Chemistry Journal.

[49]  S. Shchelkunov Emergence and reemergence of smallpox: the need for development of a new generation smallpox vaccine. , 2011, Vaccine.

[50]  M. Grell,et al.  Design and synthesis of isoquinolines and benzimidazoles as RAF kinase inhibitors. , 2011, Bioorganic & medicinal chemistry letters.

[51]  G. Andrei,et al.  Cidofovir Activity against Poxvirus Infections , 2010, Viruses.

[52]  R. Jordan,et al.  Development of ST-246® for Treatment of Poxvirus Infections , 2010, Viruses.

[53]  P. Jahrling,et al.  Countermeasures to the bioterrorist threat of smallpox. , 2005, Current molecular medicine.

[54]  T. Schutzbank,et al.  Smallpox: Residual Antibody after Vaccination , 2003, Journal of Clinical Microbiology.

[55]  M. Huycke Smallpox in the post-eradication era. , 2002, The Journal of the Oklahoma State Medical Association.

[56]  Philip K. Russell,et al.  Smallpox as a biological weapon: medical and public health management. Working Group on Civilian Biodefense. , 1999, JAMA.