Renal transplantation under cyclosporine and FK 506 for hemolytic uremic syndrome.

Hemolytic uremic syndrome (HUS) is known to be a leading cause of acute renal failure in children. When seen in adults, it may often be sporadic, or familial.1 The results of renal transplantation with cyclosporine (CyA) in patients with HUS as the cause of end-stage renal disease (ESRD) have been reported in many series.2–4 We previously reported our experience with renal transplantation for HUS under FK506 (Prograf) immunosuppression.5 In this article, we describe our overall results of kidney transplantation for renal failure due to HUS treated with either CyA or FK 506 (Prograf) as the main immunosuppressive agent.