Molecular and Cellular Characterization of the Membrane Attack Complex, C5b-9, in Alzheimer’s Disease

[1]  Douglas Walker,et al.  Inflammation and Alzheimer's disease pathogenesis , 1996, Neurobiology of Aging.

[2]  C. Glabe,et al.  Multivalent Binding of Complement Protein C1q to the Amyloid β-Peptide (Aβ) Promotes the Nucleation Phase of Aβ Aggregation , 1995 .

[3]  R. Veerhuis,et al.  Early complement components in Alzheimer's disease brains , 1995, Acta Neuropathologica.

[4]  P. Mcgeer,et al.  The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases , 1995, Brain Research Reviews.

[5]  C. Cotman,et al.  beta-Amyloid activates complement by binding to a specific region of the collagen-like domain of the C1q A chain. , 1994, Journal of immunology.

[6]  P. Mcgeer,et al.  Ultrastructural localization of complement membrane attack complex (MAC)-like immunoreactivity in brains of patients with Alzheimer's disease , 1994, Brain Research.

[7]  L. Lue,et al.  Association cortex, cerebellum, and serum concentrations of C1q and factor B in Alzheimer's disease. , 1993, Brain research. Molecular brain research.

[8]  P. Mcgeer,et al.  Complement activation by beta-amyloid in Alzheimer disease. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[9]  R. Kalaria,et al.  Complement inhibitor C4-binding protein in amyloid deposits containing serum amyloid P in Alzheimer's disease. , 1992, Biochemical and biophysical research communications.

[10]  D. Walker,et al.  Complement gene expression in human brain: comparison between normal and Alzheimer disease cases. , 1992, Brain research. Molecular brain research.

[11]  L. Lue,et al.  Full complement activation fails in diffuse plaques of the Alzheimer's disease cerebellum , 1992 .

[12]  D. Walker,et al.  Detection of the membrane inhibitor of reactive lysis (CD59) in diseased neurons of Alzheimer brain , 1991, Brain Research.

[13]  Steven A. Johnson,et al.  Dynamics of gene expression for a hippocampal glycoprotein elevated in Alzheimer's disease and in response to experimental lesions in rat , 1990, Neuron.

[14]  P. Mcgeer,et al.  Activation of the classical complement pathway in brain tissue of Alzheimer patients , 1989, Neuroscience Letters.

[15]  A. Campbell,et al.  Vesicular removal by oligodendrocytes of membrane attack complexes formed by activated complement , 1989, Nature.

[16]  P. Eikelenboom,et al.  Complement activation in amyloid plaques in Alzheimer’s dementia , 1988, Virchows Archiv. B, Cell pathology including molecular pathology.

[17]  P. Mcgeer,et al.  Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR , 1987, Neuroscience Letters.

[18]  M. Shin,et al.  Activation of Complement by Myelin: Identification of C1‐Binding Proteins of Human Myelin from Central Nervous Tissue , 1986, Journal of neurochemistry.

[19]  M. Gehring,et al.  Nucleotide sequence of cDNA and derived amino acid sequence of human complement component C9. , 1984, Proceedings of the National Academy of Sciences of the United States of America.

[20]  E. Podack Molecular composition of the tubular structure of the membrane attack complex of complement. , 1984, The Journal of biological chemistry.