Hypoxia-Inducible Factors in Acute Kidney Injury: From Pathophysiology to a Novel Approach of Organ Protection
暂无分享,去创建一个
[1] S. Bachmann,et al. Hypoxia-inducible factor-2alpha-expressing interstitial fibroblasts are the only renal cells that express erythropoietin under hypoxia-inducible factor stabilization. , 2010, Kidney international.
[2] K. Park,et al. Reactive oxygen species generated by renal ischemia and reperfusion trigger protection against subsequent renal ischemia and reperfusion injury in mice. , 2010, American journal of physiology. Renal physiology.
[3] B. Buchholz,et al. Donor treatment with a PHD-inhibitor activating HIFs prevents graft injury and prolongs survival in an allogenic kidney transplant model , 2009, Proceedings of the National Academy of Sciences.
[4] B. Buchholz,et al. HIF-prolyl hydroxylases in the rat kidney: physiologic expression patterns and regulation in acute kidney injury. , 2009, The American journal of pathology.
[5] M. Maze,et al. Xenon preconditioning protects against renal ischemic-reperfusion injury via HIF-1alpha activation. , 2009, Journal of the American Society of Nephrology : JASN.
[6] J. Gleadle. Review article: How cells sense oxygen: Lessons from and for the kidney , 2009, Nephrology.
[7] T. A. Sutton,et al. p53 regulates renal expression of HIF-1{alpha} and pVHL under physiological conditions and after ischemia-reperfusion injury. , 2008, American journal of physiology. Renal physiology.
[8] K. Eckardt,et al. Activation of hypoxia-inducible factors ameliorates hypoxic distal tubular injury in the isolated perfused rat kidney. , 2008, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
[9] David W. Smith,et al. Intrarenal oxygenation: unique challenges and the biophysical basis of homeostasis. , 2008, American journal of physiology. Renal physiology.
[10] M. Nangaku,et al. Hypoxia and Hypoxia-Inducible Factor in Renal Disease , 2008, Nephron Experimental Nephrology.
[11] C. Ince,et al. Renal Hypoxia and Dysoxia After Reperfusion of the Ischemic Kidney , 2008, Molecular medicine.
[12] W. Kaelin,et al. Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway. , 2008, Molecular cell.
[13] B. Buchholz,et al. HIF activation protects from acute kidney injury. , 2008, Journal of the American Society of Nephrology : JASN.
[14] T. Schrader,et al. Evidence for sustained renal hypoxia and transient hypoxia adaptation in experimental rhabdomyolysis-induced acute kidney injury. , 2007, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
[15] Peter Hill,et al. Inhibition of hypoxia inducible factor hydroxylases protects against renal ischemia-reperfusion injury. , 2008, Journal of the American Society of Nephrology : JASN.
[16] J. Tisdale,et al. HIF prolyl hydroxylase inhibition results in endogenous erythropoietin induction, erythrocytosis, and modest fetal hemoglobin expression in rhesus macaques. , 2007, Blood.
[17] E. Rankin,et al. Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo. , 2007, The Journal of clinical investigation.
[18] Tetsuhiro Tanaka,et al. Protective role of hypoxia-inducible factor-2alpha against ischemic damage and oxidative stress in the kidney. , 2007, Journal of the American Society of Nephrology : JASN.
[19] Roland H Wenger,et al. Increased Prolyl 4-Hydroxylase Domain Proteins Compensate for Decreased Oxygen Levels , 2006, Journal of Biological Chemistry.
[20] K. Eckardt,et al. Preconditional activation of hypoxia-inducible factors ameliorates ischemic acute renal failure. , 2006, Journal of the American Society of Nephrology : JASN.
[21] V. Haase,et al. Cytoprotective effects of hypoxia against cisplatin-induced tubular cell apoptosis: involvement of mitochondrial inhibition and p53 suppression. , 2006, Journal of the American Society of Nephrology : JASN.
[22] K. Eckardt,et al. Hypoxia-inducible factors and tubular cell survival in isolated perfused kidneys. , 2006, Kidney international.
[23] K. Eckardt,et al. Expression of hypoxia-inducible transcription factors in developing human and rat kidneys. , 2006, Kidney international.
[24] Tetsuhiro Tanaka,et al. Hypoxia-inducible factor modulates tubular cell survival in cisplatin nephrotoxicity. , 2005, American journal of physiology. Renal physiology.
[25] J. Richardson,et al. HIF-2alpha regulates murine hematopoietic development in an erythropoietin-dependent manner. , 2005, Blood.
[26] P. Reinke,et al. Up-regulation of HIF in experimental acute renal failure: evidence for a protective transcriptional response to hypoxia. , 2005, Kidney international.
[27] V. Erdmann,et al. Differentiating the functional role of hypoxia‐inducible factor (HIF)‐1α and HIF‐2α (EPAS‐1) by the use of RNA interference: erythropoietin is a HIF‐2α target gene in Hep3B and Kelly cells , 2004 .
[28] Kan Ding,et al. Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1−/− mice , 2003, Nature Genetics.
[29] Christian Frelin,et al. Hypoxia Up-regulates Prolyl Hydroxylase Activity , 2003, Journal of Biological Chemistry.
[30] K. Eckardt,et al. Cellular responses to hypoxia after renal segmental infarction. , 2003, Kidney international.
[31] M. A. Morris,et al. The HIF family member EPAS 1 / HIF-2 is required for normal hematopoiesis in mice , 2003 .
[32] Tetsuhiro Tanaka,et al. Induction of renoprotective gene expression by cobalt ameliorates ischemic injury of the kidney in rats. , 2003, Journal of the American Society of Nephrology : JASN.
[33] P. S. St. John,et al. Podocyte expression of hypoxia-inducible factor (HIF)-1 and HIF-2 during glomerular development. , 2003, Journal of the American Society of Nephrology : JASN.
[34] Kai-Uwe Eckardt,et al. The FASEB Journal express article 10.1096/fj.02-0445fje. Published online December 17, 2002. Widespread, hypoxia-inducible expression of HIF-2α in distinct cell populations of different organs , 2022 .
[35] D. Peet,et al. FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor. , 2002, Genes & development.
[36] Till Acker,et al. Loss of HIF-2α and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice , 2002, Nature Medicine.
[37] S. McKnight,et al. A Conserved Family of Prolyl-4-Hydroxylases That Modify HIF , 2001, Science.
[38] Michael I. Wilson,et al. C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation , 2001, Cell.
[39] M. Ivan,et al. HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O2 Sensing , 2001, Science.
[40] G. Semenza,et al. Defective vascularization of HIF-1alpha-null embryos is not associated with VEGF deficiency but with mesenchymal cell death. , 1999, Developmental biology.
[41] Jessica Lo,et al. HIF‐1α is required for solid tumor formation and embryonic vascularization , 1998 .
[42] M. Gassmann,et al. Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha. , 1998, Genes & development.
[43] P. Liss,et al. Intrarenal oxygen tension measured by a modified Clark electrode at normal and low blood pressure and after injection of x-ray contrast media , 1997, Pflügers Archiv.
[44] D W Lübbers,et al. Heterogeneities and profiles of oxygen pressure in brain and kidney as examples of the pO2 distribution in the living tissue. , 1997, Kidney international.
[45] D. Shoskes,et al. Effect of delayed graft function on short- and long-term kidney graft survival. , 1997, Clinical transplants.
[46] K. Baringhaus,et al. Inhibition of prolyl 4-hydroxylase by oxalyl amino acid derivatives in vitro, in isolated microsomes and in embryonic chicken tissues. , 1994, The Biochemical journal.
[47] M. Brezis,et al. Determinants of intrarenal oxygenation: factors in acute renal failure. , 1992, Renal failure.
[48] H. Baumgaertl,et al. Evidence for a preglomerular oxygen diffusion shunt in rat renal cortex. , 1990, The American journal of physiology.
[49] K. Kivirikko,et al. Syncatalytic inactivation of prolyl 4-hydroxylase by synthetic peptides containing the unphysiologic amino acid 5-oxaproline. , 1988, The Journal of biological chemistry.
[50] R. Jennings,et al. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. , 1986, Circulation.