Molecular and cellular mechanisms of myocardial failure.

[1]  G. Feuerstein,et al.  Protective effects of carvedilol in the myocardium. , 1997, The American journal of cardiology.

[2]  M. Bristow Mechanism of action of beta-blocking agents in heart failure. , 1997, The American journal of cardiology.

[3]  N. Bishopric,et al.  Atrial Natriuretic Peptide Induces Apoptosis in Neonatal Rat Cardiac Myocytes* , 1997, The Journal of Biological Chemistry.

[4]  W. Lederer,et al.  Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure. , 1997, Science.

[5]  C A Beltrami,et al.  Apoptosis in the failing human heart. , 1997, The New England journal of medicine.

[6]  E. Pennisi Superoxides Relay Ras Protein's Oncogenic Message , 1997, Science.

[7]  A. Takeshita,et al.  Role of Myocyte Nitric Oxide in β-Adrenergic Hyporesponsiveness in Heart Failure , 1997 .

[8]  P. Anversa,et al.  Angiotensin II Induces Apoptosis of Adult Ventricular MyocytesIn Vitro , 1997 .

[9]  A. Saraste,et al.  Apoptosis in human acute myocardial infarction. , 1997, Circulation.

[10]  D. Zechner,et al.  Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes. Involvement of the sphingolipid signaling cascade in cardiac cell death. , 1996, The Journal of clinical investigation.

[11]  Y. Sugishita,et al.  Inhibition of myocardial endothelin pathway improves long-term survival in heart failure , 1996, Nature.

[12]  R. Virmani,et al.  Apoptosis in myocytes in end-stage heart failure. , 1996, The New England journal of medicine.

[13]  W. Colucci Apoptosis in the heart. , 1996, The New England journal of medicine.

[14]  P. Singal,et al.  Role of oxidative stress in transition of hypertrophy to heart failure. , 1996, Journal of the American College of Cardiology.

[15]  L. Gaboury,et al.  Apoptosis in pressure overload-induced heart hypertrophy in the rat. , 1996, The Journal of clinical investigation.

[16]  J. Heath,et al.  Cardiotrophin-1 Activates a Distinct Form of Cardiac Muscle Cell Hypertrophy , 1996, The Journal of Biological Chemistry.

[17]  H. Oral,et al.  Proinflammatory cytokine levels in patients with depressed left ventricular ejection fraction: a report from the Studies of Left Ventricular Dysfunction (SOLVD). , 1996, Journal of the American College of Cardiology.

[18]  P. Tsao,et al.  Expression of inducible nitric oxide synthase in human heart failure. , 1996, Circulation.

[19]  W. Colucci Myocardial endothelin. Does it play a role in myocardial failure? , 1996, Circulation.

[20]  Y. Sugishita,et al.  Endogenous endothelin-1 participates in the maintenance of cardiac function in rats with congestive heart failure. Marked increase in endothelin-1 production in the failing heart. , 1996, Circulation.

[21]  T. Ogihara,et al.  Nitric oxide induces upregulation of Fas and apoptosis in vascular smooth muscle. , 1996, Hypertension.

[22]  D. Mann,et al.  Tumor Necrosis Factor-α and Tumor Necrosis Factor Receptors in the Failing Human Heart , 1996 .

[23]  R Aikawa,et al.  Endothelin-1 Is Involved in Mechanical Stress-induced Cardiomyocyte Hypertrophy (*) , 1996, The Journal of Biological Chemistry.

[24]  John Calvin Reed,et al.  Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats. , 1996, Laboratory investigation; a journal of technical methods and pathology.

[25]  P. Anversa,et al.  Myocyte nuclear mitotic division and programmed myocyte cell death characterize the cardiac myopathy induced by rapid ventricular pacing in dogs. , 1995, Laboratory investigation; a journal of technical methods and pathology.

[26]  E. Sonnenblick,et al.  Stretch-induced programmed myocyte cell death. , 1995, The Journal of clinical investigation.

[27]  N. Takahashi,et al.  Pressure- and volume-induced left ventricular hypertrophies are associated with distinct myocyte phenotypes and differential induction of peptide growth factor mRNAs. , 1995, Circulation.

[28]  M. Creager,et al.  Nitric Oxide Inhibits the Positive Inotropic Response to β-Adrenergic Stimulation in Humans With Left Ventricular Dysfunction , 1995 .

[29]  M. Radomski,et al.  Myocardial calcium-independent nitric oxide synthase activity is present in dilated cardiomyopathy, myocarditis, and postpartum cardiomyopathy but not in ischaemic or valvar heart disease. , 1995, British heart journal.

[30]  K. Teng,et al.  p21ras as a Common Signaling Target of Reactive Free Radicals and Cellular Redox Stress (*) , 1995, The Journal of Biological Chemistry.

[31]  J. Hare,et al.  Role of nitric oxide in the regulation of myocardial function. , 1995, Progress in cardiovascular diseases.

[32]  N. Takahashi,et al.  Interleukin-1 beta modulates the growth and phenotype of neonatal rat cardiac myocytes. , 1995, The Journal of clinical investigation.

[33]  J. Cohn Structural basis for heart failure. Ventricular remodeling and its pharmacological inhibition. , 1995, Circulation.

[34]  P. Cannon,et al.  The lethal effects of cytokine-induced nitric oxide on cardiac myocytes are blocked by nitric oxide synthase antagonism or transforming growth factor beta. , 1995, The Journal of clinical investigation.

[35]  C. H. Conrad,et al.  Myocardial fibrosis and stiffness with hypertrophy and heart failure in the spontaneously hypertensive rat. , 1995, Circulation.

[36]  C. Lowenstein,et al.  Cytokine-inducible nitric oxide synthase (iNOS) expression in cardiac myocytes. Characterization and regulation of iNOS expression and detection of iNOS activity in single cardiac myocytes in vitro. , 1994, The Journal of biological chemistry.

[37]  R. Kloner,et al.  Reperfusion injury induces apoptosis in rabbit cardiomyocytes. , 1994, The Journal of clinical investigation.

[38]  N. Takahashi,et al.  Hypertrophic stimuli induce transforming growth factor-beta 1 expression in rat ventricular myocytes. , 1994, The Journal of clinical investigation.

[39]  A. Katz The Cardiomyopathy of Overload: An Unnatural Growth Response in the Hypertrophied Heart , 1994, Annals of Internal Medicine.

[40]  C. H. Conrad,et al.  Alterations in cardiac gene expression during the transition from stable hypertrophy to heart failure. Marked upregulation of genes encoding extracellular matrix components. , 1994, Circulation research.

[41]  U. Ikeda,et al.  Neutrophil Adherence to Rat Cardiac Myocyte by Proinflammatory Cytokines , 1994, Journal of cardiovascular pharmacology.

[42]  P. Singal,et al.  Antioxidant changes in hypertrophied and failing guinea pig hearts. , 1994, The American journal of physiology.

[43]  K. Webster,et al.  Regulation of fos and jun immediate-early genes by redox or metabolic stress in cardiac myocytes. , 1994, Circulation research.

[44]  M. Wilson,et al.  Integrin-mediated collagen gel contraction by cardiac fibroblasts. Effects of angiotensin II. , 1994, Circulation research.

[45]  J. Sadoshima,et al.  Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro , 1993, Cell.

[46]  K. Weber,et al.  Effects of endothelins on collagen turnover in cardiac fibroblasts. , 1993, Cardiovascular research.

[47]  J. LaPres,et al.  Regulation of hypertrophy and atrophy in cultured adult heart cells. , 1993, Circulation research.

[48]  M. Bristow Changes in myocardial and vascular receptors in heart failure. , 1993, Journal of the American College of Cardiology.

[49]  J. Sadoshima,et al.  Critical Role of the AT1 Receptor Subtype , 2005 .

[50]  K. Chien,et al.  The alpha 1A-adrenergic receptor subtype mediates biochemical, molecular, and morphologic features of cultured myocardial cell hypertrophy. , 1993, The Journal of biological chemistry.

[51]  B. Lorell,et al.  Selective changes in cardiac gene expression during compensated hypertrophy and the transition to cardiac decompensation in rats with chronic aortic banding. , 1993, Circulation research.

[52]  T. Yue,et al.  Myocardial protection by the novel vasodilating beta-blocker, carvedilol: potential relevance of anti-oxidant activity. , 1993, Journal of hypertension. Supplement : official journal of the International Society of Hypertension.

[53]  P. Anversa,et al.  Regulation of angiotensin II receptors on ventricular myocytes after myocardial infarction in rats. , 1993, Circulation research.

[54]  J. Balligand,et al.  Abnormal contractile function due to induction of nitric oxide synthesis in rat cardiac myocytes follows exposure to activated macrophage-conditioned medium. , 1993, The Journal of clinical investigation.

[55]  D. Ganten,et al.  Selective activation of cardiac angiotensinogen gene expression in post-infarction ventricular remodeling in the rat. , 1993, Journal of molecular and cellular cardiology.

[56]  N. Alpert,et al.  Alterations in sarcoplasmic reticulum gene expression in human heart failure. A possible mechanism for alterations in systolic and diastolic properties of the failing myocardium. , 1993, Circulation research.

[57]  P. Poole‐Wilson,et al.  Nitric oxide production within cardiac myocytes reduces their contractility in endotoxemia. , 1992, The American journal of physiology.

[58]  W Grossman,et al.  Expression of dihydropyridine receptor (Ca2+ channel) and calsequestrin genes in the myocardium of patients with end-stage heart failure. , 1992, The Journal of clinical investigation.

[59]  S. Izumo,et al.  Expression of A-, B-, and C-type natriuretic peptide genes in failing and developing human ventricles. Correlation with expression of the Ca(2+)-ATPase gene. , 1992, Circulation research.

[60]  T. Takahashi,et al.  Differences in cardiac calcium release channel (ryanodine receptor) expression in myocardium from patients with end-stage heart failure caused by ischemic versus dilated cardiomyopathy. , 1992, Circulation research.

[61]  J. Sadoshima,et al.  Molecular characterization of the stretch-induced adaptation of cultured cardiac cells. An in vitro model of load-induced cardiac hypertrophy. , 1992, The Journal of biological chemistry.

[62]  S. Moncada,et al.  Induction and potential biological relevance of a Ca2+‐independent nitric oxide synthase in the myocardium , 1992, British journal of pharmacology.

[63]  E Erdmann,et al.  Intracellular Calcium Handling in Isolated Ventricular Myocytes From Patients With Terminal Heart Failure , 1992, Circulation.

[64]  M. Entman,et al.  Neutrophil adherence to isolated adult cardiac myocytes. Induction by cardiac lymph collected during ischemia and reperfusion. , 1992, The Journal of clinical investigation.

[65]  B. Parsons,et al.  Adrenergic Effects on the Biology of the Adult Mammalian Cardiocyte , 1992, Circulation.

[66]  P. Allen,et al.  Troponin T isoform expression in the normal and failing human left ventricle: a correlation with myofibrillar ATPase activity. , 1992, Basic research in cardiology.

[67]  H. Schunkert,et al.  Tissue-specific activation of cardiac angiotensin converting enzyme in experimental heart failure. , 1991, Circulation research.

[68]  K. Weber,et al.  Pathological Hypertrophy and Cardiac Interstitium: Fibrosis and Renin‐Angiotensin‐Aldosterone System , 1991, Circulation.

[69]  A. Feldman,et al.  Selective Gene Expression in Failing Human Heart: Quantification of Steady‐State Levels of Messenger RNA in Endomyocardial Biopsies Using the Polymerase Chain Reaction , 1991, Circulation.

[70]  T K Borg,et al.  Expression of collagen binding integrins during cardiac development and hypertrophy. , 1991, Circulation research.

[71]  K. Chien,et al.  Endothelin induction of inositol phospholipid hydrolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes. A paracrine mechanism for myocardial cell hypertrophy. , 1990, The Journal of biological chemistry.

[72]  H. Fillit,et al.  Elevated circulating levels of tumor necrosis factor in severe chronic heart failure. , 1990, The New England journal of medicine.

[73]  M. Sporn,et al.  Transforming Growth Factor‐β1 in Normal Heart and in Myocardial Infarction , 1990 .

[74]  G. Murrell,et al.  Modulation of fibroblast proliferation by oxygen free radicals , 1990 .

[75]  T. Parker,et al.  Peptide growth factors can provoke "fetal" contractile protein gene expression in rat cardiac myocytes. , 1990, The Journal of clinical investigation.

[76]  W. Cassells Transforming growth factor β_1 in normal heart and in myocardial infarction. , 1990 .

[77]  G. Habermehl,et al.  Human fibroblasts release reactive oxygen species in response to interleukin-1 or tumour necrosis factor-alpha. , 1989, The Biochemical journal.

[78]  P. Ludmer,et al.  Intracoronary infusion of dobutamine to patients with and without severe congestive heart failure. Dose-response relationships, correlation with circulating catecholamines, and effect of phosphodiesterase inhibition. , 1988, The Journal of clinical investigation.

[79]  G Olivetti,et al.  Quantitative structural analysis of the myocardium during physiologic growth and induced cardiac hypertrophy: a review. , 1986, Journal of the American College of Cardiology.

[80]  P. Simpson Norepinephrine-stimulated hypertrophy of cultured rat myocardial cells is an alpha 1 adrenergic response. , 1983, The Journal of clinical investigation.

[81]  T. Kiss,et al.  Effect of Ca-free medium on the ultrastructure and excitability of the myocardial cells of the snail, Helix pomatia L. , 1973, Journal of molecular and cellular cardiology.