Cell starvation regulates ceramide-induced autophagy in mouse preimplantation embryo development.

[1]  G. Cheng,et al.  Inhibition of DRP1 Impedes Zygotic Genome Activation and Preimplantation Development in Mice , 2021, Frontiers in Cell and Developmental Biology.

[2]  B. Rotblat,et al.  How does mTOR sense glucose starvation? AMPK is the usual suspect , 2020, Cell Death Discovery.

[3]  M. Maciejczyk,et al.  High-Fat Diet Affects Ceramide Content, Disturbs Mitochondrial Redox Balance, and Induces Apoptosis in the Submandibular Glands of Mice , 2019, Biomolecules.

[4]  S. Tait,et al.  Mitochondria and Inflammation: Cell Death Heats Up , 2019, Front. Cell Dev. Biol..

[5]  Xinli Hu,et al.  DPPA2/4 and SUMO E3 ligase PIAS4 opposingly regulate zygotic transcriptional program , 2019, PLoS biology.

[6]  T. Wakai,et al.  Clinical application of ceramide in cancer treatment , 2019, Breast Cancer.

[7]  Xin Zhao,et al.  Structure of the human LAT1–4F2hc heteromeric amino acid transporter complex , 2019, Nature.

[8]  H. Aanes,et al.  Parental vitamin deficiency affects the embryonic gene expression of immune-, lipid transport- and apolipoprotein genes , 2016, Scientific Reports.

[9]  R. Zoncu,et al.  Dynamics of mTORC1 activation in response to amino acids , 2016, eLife.

[10]  Y. Okada,et al.  Paternal H3K4 methylation is required for minor zygotic gene activation and early mouse embryonic development , 2015, EMBO reports.

[11]  S. Tait,et al.  Mitochondrial apoptosis: killing cancer using the enemy within , 2015, British Journal of Cancer.

[12]  N. Færgeman,et al.  Autophagy in the light of sphingolipid metabolism , 2015, Apoptosis.

[13]  Tingting Wu,et al.  Upregulation of forkhead box O3 transcription is involved in C2-ceramide induced apoptosis and autophagy in ovarian cancer cells in vitro. , 2014, Molecular medicine reports.

[14]  S. Xiong,et al.  Mitochondria-mediated apoptosis in mammals , 2014, Protein & Cell.

[15]  R. Chen,et al.  The general amino acid control pathway regulates mTOR and autophagy during serum/glutamine starvation , 2014, The Journal of cell biology.

[16]  Kun-Liang Guan,et al.  Autophagy regulation by nutrient signaling , 2013, Cell Research.

[17]  Lei Li,et al.  The maternal to zygotic transition in mammals. , 2013, Molecular aspects of medicine.

[18]  Hong Li,et al.  Sphingosine-1-phosphate inhibits ceramide-induced apoptosis during murine preimplantation embryonic development. , 2013, Theriogenology.

[19]  A. Criollo,et al.  Calcium and mitochondrial metabolism in ceramide-induced cardiomyocyte death. , 2013, Biochimica et biophysica acta.

[20]  Yuan-Qing Yao,et al.  Special nutrition in mouse developmental oocytes. , 2012, Experimental and therapeutic medicine.

[21]  Nam-Hyung Kim,et al.  mTOR is required for asymmetric division through small GTPases in mouse oocytes , 2012, Molecular reproduction and development.

[22]  Terry K. Smith,et al.  Sphingolipid and Ceramide Homeostasis: Potential Therapeutic Targets , 2012, Biochemistry research international.

[23]  Xiaofeng Zhu,et al.  c-Jun NH2-terminal kinase activation is essential for up-regulation of LC3 during ceramide-induced autophagy in human nasopharyngeal carcinoma cells , 2011, Journal of Translational Medicine.

[24]  Nam-Hyung Kim,et al.  Modulation of autophagy influences development and apoptosis in mouse embryos developing in vitro , 2011, Molecular reproduction and development.

[25]  Y. Hannun,et al.  Many Ceramides* , 2011, The Journal of Biological Chemistry.

[26]  E. Wolf,et al.  Increase of essential amino acids in the bovine uterine lumen during preimplantation development. , 2011, Reproduction.

[27]  B. Viollet,et al.  AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1 , 2011, Nature Cell Biology.

[28]  Daniel J Klionsky,et al.  Mammalian autophagy: core molecular machinery and signaling regulation. , 2010, Current opinion in cell biology.

[29]  B. Thorens,et al.  Glucose transporters in the 21st Century. , 2010, American journal of physiology. Endocrinology and metabolism.

[30]  J. Padbury,et al.  LAT-1 expression in pre- and post-implantation embryos and placenta. , 2009, Placenta.

[31]  A. Edinger Starvation in the midst of plenty: making sense of ceramide-induced autophagy by analysing nutrient transporter expression. , 2009, Biochemical Society transactions.

[32]  Eigen R. Peralta,et al.  Ceramide starves cells to death by downregulating nutrient transporter proteins , 2008, Proceedings of the National Academy of Sciences.

[33]  N. Mizushima,et al.  The role of autophagy during the oocyte-to-embryo transition , 2008, Autophagy.

[34]  M. Murakami,et al.  Autophagy Is Essential for Preimplantation Development of Mouse Embryos , 2008, Science.

[35]  M. Pantaleon,et al.  Nutrient Sensing by the Early Mouse Embryo: Hexosamine Biosynthesis and Glucose Signaling During Preimplantation Development1 , 2008 .

[36]  Daniel J. Klionsky,et al.  Autophagy fights disease through cellular self-digestion , 2008, Nature.

[37]  M. De Felici,et al.  Analysis of programmed cell death in mouse fetal oocytes. , 2007, Reproduction.

[38]  D. Rubinsztein,et al.  Atg5 and Bcl-2 provide novel insights into the interplay between apoptosis and autophagy , 2007, Cell Death and Differentiation.

[39]  Thomas Schaffner,et al.  Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis , 2006, Nature Cell Biology.

[40]  J. Thundathil,et al.  Molecular control of mitochondrial function in preimplantation mouse embryos , 2005, Molecular reproduction and development.

[41]  É. Hajduch,et al.  Ceramide down‐regulates System A amino acid transport and protein synthesis in rat skeletal muscle cells , 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[42]  Philippe Dessen,et al.  Inhibition of Macroautophagy Triggers Apoptosis , 2005, Molecular and Cellular Biology.

[43]  Yusuf A. Hannun,et al.  Biologically active sphingolipids in cancer pathogenesis and treatment , 2004, Nature Reviews Cancer.

[44]  C. Bauvy,et al.  Ceramide-mediated Macroautophagy Involves Inhibition of Protein Kinase B and Up-regulation of Beclin 1* , 2004, Journal of Biological Chemistry.

[45]  T. Golub,et al.  The Immunosuppressant Rapamycin Mimics a Starvation-Like Signal Distinct from Amino Acid and Glucose Deprivation , 2002, Molecular and Cellular Biology.

[46]  C. Thompson,et al.  Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake. , 2002, Molecular biology of the cell.

[47]  Thomas D. Schmittgen,et al.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.

[48]  E. Heinz,et al.  Glucosylceramide Synthases, a Gene Family Responsible for the Biosynthesis of Glucosphingolipids in Animals, Plants, and Fungi* , 2001, The Journal of Biological Chemistry.

[49]  H. Yonekawa,et al.  Selective and continuous elimination of mitochondria microinjected into mouse eggs from spermatids, but not from liver cells, occurs throughout embryogenesis. , 2000, Genetics.

[50]  Honglin Zhou,et al.  Regulation of Insulin-Stimulated Glucose Transporter GLUT4 Translocation and Akt Kinase Activity by Ceramide , 1998, Molecular and Cellular Biology.

[51]  M. Mueckler,et al.  Maternal hyperglycemia alters glucose transport and utilization in mouse preimplantation embryos. , 1998, American journal of physiology. Endocrinology and metabolism.

[52]  D. Brindley,et al.  Effects of Cell-Permeable Ceramides and Tumor Necrosis Factor-α on Insulin Signaling and Glucose Uptake in 3T3-L1 Adipocytes , 1998, Diabetes.

[53]  P. Pekala,et al.  Lipid mediators of insulin resistance: ceramide signalling down-regulates GLUT4 gene transcription in 3T3-L1 adipocytes. , 1996, The Biochemical journal.

[54]  S. Vannucci Developmental Expression of GLUT1 and GLUT3 Glucose Transporters in Rat Brain , 1994, Journal of neurochemistry.

[55]  Y. Hannun,et al.  Programmed cell death induced by ceramide. , 1993, Science.

[56]  Peter W. J. Rigby,et al.  A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo , 1990, Nature.

[57]  C. Chalfant,et al.  The Role of Ceramide 1-Phosphate in Inflammation, Cellular Proliferation, and Wound Healing. , 2019, Advances in experimental medicine and biology.

[58]  H. Asada,et al.  Long-chain glucosylceramides crosstalk with LYN mediates endometrial cell migration. , 2018, Biochimica et biophysica acta. Molecular and cell biology of lipids.

[59]  E. Bieberich,et al.  Ceramide and S1P Signaling in Embryonic Stem Cell Differentiation. , 2018, Methods in molecular biology.

[60]  W. Hay Placental-fetal glucose exchange and fetal glucose metabolism. , 2006, Transactions of the American Clinical and Climatological Association.

[61]  J. Thundathil,et al.  Role of the mitochondrial genome in preimplantation development and assisted reproductive technologies. , 2005, Reproduction, fertility, and development.

[62]  G. Owen,et al.  Glucose transporters: expression, regulation and cancer. , 2002, Biological research.