Multiantigen/multiepitope-directed immune-specific suppression of "complex autoimmune encephalomyelitis" by a novel protein product of a synthetic gene.
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[1] V. Tuohy. Peptide determinants of myelin proteolipid protein (PLP) in autoimmune demyelinating disease: A review , 1994, Neurochemical Research.
[2] T‐cell responses to oligodendrocyte‐specific protein in multiple sclerosis , 2001, Journal of neuroscience research.
[3] A. Evans,et al. Induction of a non-encephalitogenic type 2 T helper-cell autoimmune response in multiple sclerosis after administration of an altered peptide ligand in a placebo-controlled, randomized phase II trial , 2000, Nature Medicine.
[4] J. Frank,et al. Encephalitogenic potential of the myelin basic protein peptide (amino acids 83–99) in multiple sclerosis: Results of a phase II clinical trial with an altered peptide ligand , 2000, Nature Medicine.
[5] M. Wauben,et al. Anergic T cells as active regulators of the immune response. , 2000, Human immunology.
[6] K. Legge,et al. Coupling of Peripheral Tolerance to Endogenous Interleukin 10 Promotes Effective Modulation of Myelin-Activated T Cells and Ameliorates Experimental Allergic Encephalomyelitis , 2000, The Journal of experimental medicine.
[7] A. Meshorer,et al. T-cells specific for soluble recombinant oligodendrocyte-specific protein induce severe clinical experimental autoimmune encephalomyelitis in H-2b and H-2s mice , 2000, Journal of Neuroimmunology.
[8] M. Kamoun,et al. Mechanisms of suppression of experimental autoimmune encephalomyelitis by intravenous administration of myelin basic protein: role of regulatory spleen cells. , 2000, Experimental and molecular pathology.
[9] A. Ben-nun,et al. The central nervous sytem-specific myelin oligodendrocytic basic protein (MOBP) is encephalitogenic and a potential target antigen in multiple sclerosis (MS) , 2000, Journal of Neuroimmunology.
[10] Roland Martin,et al. Myelin-Associated Oligodendrocytic Basic Protein: Identification of an Encephalitogenic Epitope and Association with Multiple Sclerosis1 , 2000, The Journal of Immunology.
[11] J. Bronstein,et al. Oligodendrocyte-specific protein peptides induce experimental autoimmune encephalomyelitis in SJL/J mice. , 1999, Journal of immunology.
[12] V. Tuohy,et al. Spontaneous Regression of Primary Autoreactivity during Chronic Progression of Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis , 1999, The Journal of experimental medicine.
[13] A. Ben-nun,et al. Experimental Autoimmune Encephalomyelitis Induced by Various Antigens of the Central Nervous System: Overview and Relevance to Multiple Sclerosis , 1999 .
[14] A. Ben-nun,et al. T-cell responses to myelin antigens in multiple sclerosis; relevance of the predominant autoimmune reactivity to myelin oligodendrocyte glycoprotein. , 1998, Journal of autoimmunity.
[15] G. Sunshine,et al. Experimental autoimmune encephalomyelitis induced with a combination of myelin basic protein and myelin oligodendrocyte glycoprotein is ameliorated by administration of a single myelin basic protein peptide. , 1998, Journal of immunology.
[16] H. McFarland,et al. T cell recognition of myelin proteolipid protein and myelin proteolipid protein peptides in the peripheral blood of multiple sclerosis and control subjects , 1998, Journal of Neuroimmunology.
[17] Hervé Groux,et al. A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis , 1997, Nature.
[18] R. Kinkel,et al. Diversity and plasticity of self recognition during the development of multiple sclerosis. , 1997, The Journal of clinical investigation.
[19] L. Matis,et al. Treatment of experimental encephalomyelitis with a novel chimeric fusion protein of myelin basic protein and proteolipid protein. , 1996, The Journal of clinical investigation.
[20] A. Ben-nun,et al. Delineation of the minimal encephalitogenic epitope within the immunodominant region of myelin oligodendrocyte glycoprotein: diverse Vβ gene usage by T cells recognizing the core epitope encephalitogenic for T cell receptor Vβb and T cell receptor Vβa H‐2b mice , 1996 .
[21] M. Zhao,et al. Active and passive experimental autoimmune encephalomyelitis in strain 129/J (H‐2b) mice , 1996, Journal of neuroscience research.
[22] R. Coffman,et al. A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells , 1996, The Journal of experimental medicine.
[23] K. Shokat,et al. Intravenous injection of soluble antigen induces thymic and peripheral T-cells apoptosis. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[24] V. Tuohy,et al. A predictable sequential determinant spreading cascade invariably accompanies progression of experimental autoimmune encephalomyelitis: a basis for peptide-specific therapy after onset of clinical disease , 1996, The Journal of experimental medicine.
[25] S. Miller,et al. Functional evidence for epitope spreading in the relapsing pathology of experimental autoimmune encephalomyelitis , 1995, The Journal of experimental medicine.
[26] J. Goverman,et al. T cell deletion in high antigen dose therapy of autoimmune encephalomyelitis. , 1994, Science.
[27] A. Ben-nun,et al. Protection against autoimmune disease by bacterial agents. II. PPD and pertussis toxin as proteins active in protecting mice against experimental autoimmune encephalomyelitis , 1993, European journal of immunology.
[28] H. Burstein,et al. In vivo role of interleukin 4 in T cell tolerance induced by aqueous protein antigen , 1993, The Journal of experimental medicine.
[29] E. Sercarz,et al. Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen , 1992, Nature.
[30] H. Burstein,et al. Aqueous antigens induce in vivo tolerance selectively in IL-2- and IFN-gamma-producing (Th1) cells. , 1992, Journal of immunology.
[31] J. Trotter,et al. T cell sensitization to proteolipid protein in myelin basic protein-induced relapsing experimental allergic encephalomyelitis , 1991, Journal of Neuroimmunology.
[32] R. McCarron,et al. Alterations in T cell antigen specificity and class II restriction during the course of chronic relapsing experimental allergic encephalomyelitis , 1990, Journal of Neuroimmunology.
[33] J. Kamholz,et al. Identification of three forms of human myelin basic protein by cDNA cloning. , 1986, Proceedings of the National Academy of Sciences of the United States of America.
[34] A. Ben-nun,et al. Detection of autoimmune cells proliferating to myelin basic protein and selection of T cell lines that mediate experimental autoimmune encephalomyelitis (EAE) in mice. , 1983, Journal of immunology.