Direct evidence of abca1-mediated efflux of cholesterol at the mouse blood–brain barrier

[1]  P. Dodd,et al.  Housekeepers for accurate transcript expression analysis in Alzheimer's disease autopsy brain tissue , 2010, Alzheimer's & Dementia.

[2]  Marie-Anne Loriot,et al.  ABC transporters and cytochromes P450 in the human central nervous system: influence on brain pharmacokinetics and contribution to neurodegenerative disorders , 2010, Expert opinion on drug metabolism & toxicology.

[3]  N. Fitz,et al.  The role of ATP-binding cassette transporter A1 in Alzheimer's disease and neurodegeneration. , 2010, Biochimica et biophysica acta.

[4]  A. Graham,et al.  Overexpression of steroidogenic acute regulatory protein increases macrophage cholesterol efflux to apolipoprotein AI. , 2010, Cardiovascular research.

[5]  T. Kusaka,et al.  Transporters in the brain endothelial barrier. , 2010, Current medicinal chemistry.

[6]  Curtis D. Klaassen,et al.  Xenobiotic, Bile Acid, and Cholesterol Transporters: Function and Regulation , 2010, Pharmacological Reviews.

[7]  C. Weickert,et al.  SELECTION OF REFERENCE GENE EXPRESSION IN A SCHIZOPHRENIA BRAIN COHORT , 2010, Schizophrenia Research.

[8]  R. Kim,et al.  Blood−brain barrier transporters and response to CNS-active drugs , 2009, European Journal of Clinical Pharmacology.

[9]  S. D. de Morais,et al.  Comparative gene expression profiles of ABC transporters in brain microvessel endothelial cells and brain in five species including human. , 2009, Pharmacological research.

[10]  G. M. Pollack,et al.  Assessment of Blood–Brain Barrier Permeability Using the In Situ Mouse Brain Perfusion Technique , 2009, Pharmaceutical Research.

[11]  M. Hayden,et al.  Specific Loss of Brain ABCA1 Increases Brain Cholesterol Uptake and Influences Neuronal Structure and Function , 2009, The Journal of Neuroscience.

[12]  J. Nicolazzo,et al.  Drug transport across the blood-brain barrier and the impact of breast cancer resistance protein (ABCG2). , 2009, Current topics in medicinal chemistry.

[13]  L. Fenart,et al.  Transcriptional profiles of receptors and transporters involved in brain cholesterol homeostasis at the blood–brain barrier: Use of an in vitro model , 2009, Brain Research.

[14]  S. Cisternino,et al.  In Situ Mouse Carotid Perfusion Model: Glucose and Cholesterol Transport in the Eye and Brain , 2008, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[15]  K. Beyreuther,et al.  Independent Inhibition of Alzheimer Disease β- and γ-Secretase Cleavage by Lowered Cholesterol Levels* , 2008, Journal of Biological Chemistry.

[16]  John Woulfe,et al.  Cholesterol retention in Alzheimer's brain is responsible for high β- and γ-secretase activities and Aβ production , 2008, Neurobiology of Disease.

[17]  T. Abe,et al.  Brain‐to‐blood elimination of 24S‐hydroxycholesterol from rat brain is mediated by organic anion transporting polypeptide 2 (oatp2) at the blood–brain barrier , 2007, Journal of neurochemistry.

[18]  V. Meininger,et al.  Minocycline and riluzole brain disposition: interactions with p‐glycoprotein at the blood–brain barrier , 2007, Journal of neurochemistry.

[19]  Lilit Vardanian,et al.  The effects of ABCA1 on cholesterol efflux and Aβ levels in vitro and in vivo , 2006, Journal of neurochemistry.

[20]  C. Lim,et al.  Quantitation of ATP-binding cassette subfamily-A transporter gene expression in primary human brain cells , 2006, Neuroreport.

[21]  Jonathan D. Smith,et al.  Reevaluation of the role of the multidrug-resistant P-glycoprotein in cellular cholesterol homeostasis Published, JLR Papers in Press, October 7, 2005. , 2006, Journal of Lipid Research.

[22]  E. Favari,et al.  Probucol Inhibits ABCA1-Mediated Cellular Lipid Efflux , 2004, Arteriosclerosis, thrombosis, and vascular biology.

[23]  H. Takanaga,et al.  mRNA expression of the ATP-binding cassette transporter subfamily A (ABCA) in rat and human brain capillary endothelial cells. , 2004, Biological & pharmaceutical bulletin.

[24]  J. Genest,et al.  Molecular interactions between apoE and ABCA1: impact on apoE lipidation. , 2004, Journal of lipid research.

[25]  S. Cisternino,et al.  Expression, up-regulation, and transport activity of the multidrug-resistance protein Abcg2 at the mouse blood-brain barrier. , 2004, Cancer research.

[26]  D. Russell,et al.  Quantitation of two pathways for cholesterol excretion from the brain in normal mice and mice with neurodegeneration Published, JLR Papers in Press, June 16, 2003. DOI 10.1194/jlr.M300164-JLR200 , 2003, Journal of Lipid Research.

[27]  T. Janvilisri,et al.  Sterol Transport by the Human Breast Cancer Resistance Protein (ABCG2) Expressed in Lactococcus lactis* , 2003, Journal of Biological Chemistry.

[28]  C. Rousselle,et al.  Apparent Lack of Mrp1-Mediated Efflux at the Luminal Side of Mouse Blood-Brain Barrier Endothelial Cells , 2003, Pharmaceutical Research.

[29]  M. Linton,et al.  Reverse Transcriptase-Polymerase Chain Reaction , 2020, Definitions.

[30]  Z. Balázs,et al.  ABCA1 and Scavenger Receptor Class B, Type I, Are Modulators of Reverse Sterol Transport at an in Vitro Blood-Brain Barrier Constituted of Porcine Brain Capillary Endothelial Cells* , 2002, The Journal of Biological Chemistry.

[31]  B. McManus,et al.  ABCA1 mRNA and Protein Distribution Patterns Predict Multiple Different Roles and Levels of Regulation , 2002, Laboratory Investigation.

[32]  C. Gabel,et al.  High density lipoprotein deficiency and foam cell accumulation in mice with targeted disruption of ATP-binding cassette transporter-1. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[33]  C. Rousselle,et al.  New advances in the transport of doxorubicin through the blood-brain barrier by a peptide vector-mediated strategy. , 2000, Molecular pharmacology.

[34]  Christophe Rousselle,et al.  Development of an In Situ Mouse Brain Perfusion Model and its Application to mdr1a P-Glycoprotein-Deficient Mice , 2000, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[35]  D. Lütjohann,et al.  Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[36]  P. Morell,et al.  Cholesterol for Synthesis of Myelin Is Made Locally, Not Imported into Brain , 1995, Journal of neurochemistry.

[37]  R. Béliveau,et al.  Purification and characterization of metabolically active capillaries of the blood-brain barrier. , 1991, The Biochemical journal.

[38]  W. Pardridge,et al.  Capillary Depletion Method for Quantification of Blood–Brain Barrier Transport of Circulating Peptides and Plasma Proteins , 1990, Journal of neurochemistry.

[39]  S. Rapoport,et al.  An in situ brain perfusion technique to study cerebrovascular transport in the rat. , 1984, The American journal of physiology.

[40]  W. Pardridge,et al.  Palmitate and Cholesterol Transport Through the Blood‐Brain Barrier , 1980, Journal of neurochemistry.

[41]  D. Elliott,et al.  Increased ATP-binding cassette transporter A1 expression in Alzheimer's disease hippocampal neurons. , 2010, Journal of Alzheimer's disease : JAD.

[42]  L. Lue,et al.  Cholesterol retention in Alzheimer's brain is responsible for high beta- and gamma-secretase activities and Abeta production. , 2008, Neurobiology of disease.

[43]  T. Ishikawa,et al.  Human ABC transporters ABCG2 (BCRP) and ABCG4. , 2008, Xenobiotica; the fate of foreign compounds in biological systems.