Regression of pulmonary metastatic disease associated with intralesional bcg therapy of intracutaneous melanoma metastases

A 77‐year‐old white man with 64 intracutaneous melanoma metastases and a pulmonary metastatic deposit was treated with immunotherapy. Over an 8‐month period, 17 intracutaneous lesions were inoculated with BCG. All 17 injected lesions and all 47 uninjected intracutaneous lesions resolved; no new nodules appeared and the pulmonary metastasis regressed (> 50%). This is the first documeted case of a pulmonary metastatic focus responding to intralesional BCG therapy of intracutaneous metastases.