Pharmacokinetics, tissue distribution, and excretion of Korean Red ginseng components using radioisotopes in a rat model
暂无分享,去创建一个
Sung Won Kim | S. Hyun | S. So | Chang-Kyun Han | Gyo In | Chae-Kyu Park | Byung-Cheol Han
[1] D. Oh,et al. Complete conversion of all typical glycosylated protopanaxatriol ginsenosides to aglycon protopanaxatriol by combined bacterial β-glycosidases , 2018, AMB Express.
[2] Bi-hong Hong,et al. A Study of 11-[3H]-Tetrodotoxin Absorption, Distribution, Metabolism and Excretion (ADME) in Adult Sprague-Dawley Rats , 2017, Marine drugs.
[3] Dong-Hyun Kim. Gut microbiota-mediated pharmacokinetics of ginseng saponins , 2017, Journal of ginseng research.
[4] Xinya Duan,et al. Anticancer effects of ginsenoside Rg3 (Review). , 2017, International journal of molecular medicine.
[5] W. Setzer,et al. Ginsenoside Rb1 as a neuroprotective agent: A review , 2016, Brain Research Bulletin.
[6] J. Wan,et al. Anticancer Activities of Protopanaxadiol- and Protopanaxatriol-Type Ginsenosides and Their Metabolites , 2016, Evidence-based complementary and alternative medicine : eCAM.
[7] Ming-qing Li,et al. The antitumor activity study of ginsenosides and metabolites in lung cancer cell. , 2016, American journal of translational research.
[8] Seong-eun Park,et al. Biotransformation of major ginsenosides in ginsenoside model culture by lactic acid bacteria , 2015, Journal of ginseng research.
[9] Min-Jung Seo,et al. Ginsenoside Rg1 suppresses early stage of adipocyte development via activation of C/EBP homologous protein-10 in 3T3-L1 and attenuates fat accumulation in high fat diet-induced obese zebrafish , 2015, Journal of ginseng research.
[10] Deok-Chun Yang,et al. Biosynthesis and biotechnological production of ginsenosides. , 2015, Biotechnology advances.
[11] Sang Myung Lee,et al. Characterization of Korean Red Ginseng (Panax ginseng Meyer): History, preparation method, and chemical composition , 2015, Journal of ginseng research.
[12] Hyuck-Jai Choi,et al. Anti-stress effects of 20(S)-protopanaxadiol and 20(S)-protopanaxatriol in immobilized mice. , 2015, Biological & pharmaceutical bulletin.
[13] S. Kwon,et al. Chemical diversity of ginseng saponins from Panax ginseng☆ , 2015, Journal of ginseng research.
[14] Shuying Liu,et al. Chemical and antihyperglycemic activity changes of ginseng pectin induced by heat processing. , 2014, Carbohydrate polymers.
[15] J. Ro,et al. 20(S)-Protopanaxatriol inhibits release of inflammatory mediators in immunoglobulin E-mediated mast cell activation , 2014, Journal of ginseng research.
[16] H. Zhai,et al. Effects of Ginsenoside Rg1 on the Expression of Toll-Like Receptor 3, 4 and Their Signalling Transduction Factors in the NG108-15 Murine Neuroglial Cell Line , 2014, Molecules.
[17] Jong-Hoon Kim,et al. A review on the medicinal potentials of ginseng and ginsenosides on cardiovascular diseases , 2014, Journal of ginseng research.
[18] Hyung-Ki Kim. Pharmacokinetics of ginsenoside Rb1 and its metabolite compound K after oral administration of Korean Red Ginseng extract , 2013, Journal of ginseng research.
[19] Q. Wang,et al. Different pharmacokinetics of the two structurally similar dammarane sapogenins, protopanaxatriol and protopanaxadiol, in rats. , 2013, Fitoterapia.
[20] Dong Hyun Kim,et al. Ginseng in Traditional Herbal Prescriptions , 2012, Journal of ginseng research.
[21] Meng Chen,et al. Panax notoginseng and its components decreased hypertension via stimulation of endothelial-dependent vessel dilatation. , 2012, Vascular pharmacology.
[22] Hui Wang,et al. Ginsenosides as Anticancer Agents: In vitro and in vivo Activities, Structure–Activity Relationships, and Molecular Mechanisms of Action , 2012, Front. Pharmacol..
[23] J. Wan,et al. Comparative study on saponin fractions from Panax notoginseng inhibiting inflammation-induced endothelial adhesion molecule expression and monocyte adhesion , 2011, Chinese medicine.
[24] C. Leung,et al. 20(S)-Protopanaxadiol, a metabolite of ginsenosides, induced cell apoptosis through endoplasmic reticulum stress in human hepatocarcinoma HepG2 cells. , 2011, European journal of pharmacology.
[25] Yan Wu,et al. North American ginseng protects the heart from ischemia and reperfusion injury via upregulation of endothelial nitric oxide synthase. , 2011, Pharmacological research.
[26] N. Gu,et al. Ginsenoside Rg1 Enhances Endothelial Progenitor Cell Angiogenic Potency and Prevents Senescence In Vitro , 2011, The Journal of international medical research.
[27] Zhi Wang,et al. Ginsenoside Rb1 prevents homocysteine-induced endothelial dysfunction via PI3K/Akt activation and PKC inhibition. , 2011, Biochemical pharmacology.
[28] J. Chen,et al. Development of a UPLC-ESI-MS/MS Assay for 20(S)-Protopanaxadiol and Pharmacokinetic Application of Its Two Formulations in Rats , 2010, Analytical sciences : the international journal of the Japan Society for Analytical Chemistry.
[29] Sun-Mee Lee,et al. The effects of ginseng total saponin, panaxadiol and panaxatriol on ischemia/reperfusion injury in isolated rat heart. , 2010, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[30] Xiumei Gao,et al. Absorption and Disposition of Ginsenosides after Oral Administration of Panax notoginseng Extract to Rats , 2009, Drug Metabolism and Disposition.
[31] L. Sheng,et al. Sensitive determination of 20(S)-protopanaxadiol in rat plasma using HPLC-APCI-MS: application of pharmacokinetic study in rats. , 2008, Journal of pharmaceutical and biomedical analysis.
[32] Sung Dae Kim,et al. Protopanaxadiol modulates LPS-induced inflammatory activity in murinemacrophage RAW264.7 cells , 2006 .
[33] Z. Cai,et al. In vivo rat metabolism and pharmacokinetic studies of ginsenoside Rg3. , 2005, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
[34] M. Schubert-Zsilavecz,et al. Degradation of ginsenosides in humans after oral administration. , 2003, Drug metabolism and disposition: the biological fate of chemicals.
[35] Xiao-ling Fang,et al. Pharmacokinetics and bioavailability of ginsenoside Rb1 and Rg1 from Panax notoginseng in rats. , 2003, Journal of ethnopharmacology.
[36] E. Perry,et al. Non‐ginsenoside nicotinic activity in ginseng species , 1999, Phytotherapy research : PTR.
[37] Y. Benno,et al. Role of Human Intestinal Prevotella oris in Hydrolyzing Ginseng Saponins , 1997, Planta medica.
[38] Y. Yoo,et al. Inhibitory effect of tumor metastasis in mice by saponins, ginsenoside-Rb2, 20(R)- and 20(S)-ginsenoside-Rg3, of red ginseng. , 1995, Biological & pharmaceutical bulletin.
[39] T. Miyase,et al. Studies on absorption, distribution, excretion and metabolism of ginseng saponins. VII. Comparison of the decomposition modes of ginsenoside-Rb1 and -Rb2 in the digestive tract of rats. , 1991, Chemical & pharmaceutical bulletin.
[40] M. Nagai,et al. Chemical Studies on the Oriental Plant Drugs. XXVIII. Saponins and Sapogenins of Ginseng : Stereochemistry of the Sapogenin of Ginsenosides-Rb1, -Rb2 and -Rc , 1972 .
[41] Guo-ping Yang,et al. A review of biotransformation and pharmacology of ginsenoside compound K. , 2015, Fitoterapia.
[42] Lars P Christensen,et al. Ginsenosides chemistry, biosynthesis, analysis, and potential health effects. , 2009, Advances in food and nutrition research.
[43] Jae-Kwan Hwang,et al. Ginsenoside 20(S)-Protopanaxatriol (PPT) activates peroxisome proliferator-activated receptor γ (PPARγ) in 3T3-L1 adipocytes , 2006 .
[44] 刘勇,et al. Metabolism and pharmacokinetics of ginsenosides , 2006 .