Physiological effects of extremely high x-ray intensities and dosages on mice.

The physiological effects of high-intensity x-irradiation (2 x 105 r/min.) and dosages of 1 x 106 r on mice (head and abdomen) were investigated. An increase in pulmonary and heart rates were observed. Electrocardiographic recordings after irradiation demonstrated reversal of wave components and increase of amplitudes. Blood counts present no changes except for a drop in leukocyte counts. Hemoglobin remained unchanged. A considerable increase in serum potassium was noted and some indications of methemoglobin production. Head-irradiated animals yielded a higher incidence of auricular congestion and brain hemorrhage in contrast to animals receiving abdominal irradiation.