Simple and an efficient method for the synthesis of 1-[2-dimethylamino-1-(4-methoxy-phenyl)-ethyl]-cyclohexanol hydrochloride: (+/-) venlafaxine racemic mixtures.
暂无分享,去创建一个
[1] S. Preskorn,et al. Evidence of the dual mechanisms of action of venlafaxine. , 2000, Archives of general psychiatry.
[2] H. Brown,et al. Diborane as a Mild Reducing Agent for the Conversion of Primary, Secondary, and Tertiary Amides into the Corresponding Amines , 1964 .
[3] C. Tilford,et al. Diuretics. α,α-Disubstituted 2-Piperidine-ethanols and 3,3-Disubstituted Octahydropyrid[1,2-c]oxazines , 1954 .
[4] S. Montgomery. Predicting response: noradrenaline reuptake inhibition. , 1999, International clinical psychopharmacology.
[5] Feighner Jp. The new generation of antidepressants. , 1983 .
[6] H. Brown,et al. Selective reductions. XII. Explorations in some representative applications of aluminum hydride for selective reductions , 1968 .
[7] M. James,et al. 2-Phenyl-2-(1-hydroxycycloalkyl)ethylamine derivatives: synthesis and antidepressant activity. , 1990, Journal of medicinal chemistry.
[8] J. Zajecka. Importance of establishing the diagnosis of persistent anxiety. , 1997, The Journal of clinical psychiatry.
[9] J. Seyden-Penne,et al. Factors controlling the regioselectivity of additions to α-enones—VI: Reactions of acetonitrile and phenylacetonitrile anions , 1978 .