LNA derivatives of a kissing aptamer targeted to the trans-activating responsive RNA element of HIV-1.
暂无分享,去创建一个
[1] Ignacio Tinoco,et al. Unusual mechanical stability of a minimal RNA kissing complex , 2006, Proceedings of the National Academy of Sciences.
[2] C. Di Primo,et al. Aptamers targeted to an RNA hairpin show improved specificity compared to that of complementary oligonucleotides. , 2006, Biochemistry.
[3] Deepak Bhatnagar,et al. Promising nucleic acid analogs and mimics: characteristic features and applications of PNA, LNA, and morpholino , 2006, Applied Microbiology and Biotechnology.
[4] G. Palù,et al. Inhibitors of HIV-1 Tat-mediated transactivation. , 2006, Current medicinal chemistry.
[5] J. Toulmé,et al. Hexitol nucleic acid-containing aptamers are efficient ligands of HIV-1 TAR RNA. , 2005, Biochemistry.
[6] B. Peterlin,et al. A New Paradigm in Eukaryotic Biology: HIV Tat and the Control of Transcriptional Elongation , 2005, PLoS biology.
[7] C. Wahlestedt,et al. Locked nucleic acid (LNA) mediated improvements in siRNA stability and functionality , 2005, Nucleic acids research.
[8] J. Wengel,et al. LNA (locked nucleic acid): high-affinity targeting of complementary RNA and DNA. , 2004, Biochemistry.
[9] J. Wengel,et al. Locked nucleic acid: a potent nucleic acid analog in therapeutics and biotechnology. , 2004, Oligonucleotides.
[10] S. Douthwaite,et al. Improved RNA cleavage by LNAzyme derivatives of DNAzymes. , 2004, Biochemical Society transactions.
[11] C. Di Primo,et al. Molecular dynamics reveals the stabilizing role of loop closing residues in kissing interactions: comparison between TAR-TAR* and TAR-aptamer. , 2003, Nucleic acids research.
[12] C. Di Primo,et al. 2'-O-methyl-RNA hairpins generate loop-loop complexes and selectively inhibit HIV-1 Tat-mediated transcription. , 2002, Biochemistry.
[13] C. Di Primo,et al. Loop–loop interaction of HIV-1 TAR RNA with N3′ → P5′ deoxyphosphoramidate aptamers inhibits in vitro Tat-mediated transcription , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[14] Michael Petersen,et al. Locked nucleic acid (LNA) recognition of RNA: NMR solution structures of LNA:RNA hybrids. , 2002, Journal of the American Chemical Society.
[15] J. Wengel,et al. NUCLEOSIDES, NUCLEOTIDES & NUCLEIC ACIDS, 20(4–7), 389–396 (2001) LNA (LOCKED NUCLEIC ACID) AND THE DIASTEREOISOMERIC α-L-LNA: CONFORMATIONAL TUNING AND HIGH-AFFINITY RECOGNITION OF DNA/RNA TARGETS , 2003 .
[16] M. Egli,et al. Synthetic oligonucleotides as RNA mimetics: 2′-modified RNAs and N3′→P5′ phosphoramidates , 2000, Cellular and Molecular Life Sciences CMLS.
[17] J. Wengel,et al. Structural studies of LNA:RNA duplexes by NMR: conformations and implications for RNase H activity. , 2000, Chemistry.
[18] A. Shilatifard,et al. Control of elongation by RNA polymerase II. , 2000, Trends in biochemical sciences.
[19] F. Ducongé,et al. Is a Closing “GA Pair” a Rule for Stable Loop-Loop RNA Complexes?* , 2000, The Journal of Biological Chemistry.
[20] F. Ducongé,et al. In vitro selection identifies key determinants for loop-loop interactions: RNA aptamers selective for the TAR RNA element of HIV-1. , 1999, RNA.
[21] D. Crothers,et al. Characterization of the solution conformations of unbound and Tat peptide-bound forms of HIV-1 TAR RNA. , 1999, Biochemistry.
[22] J. Toulmé,et al. DNA Aptamers Selected Against the HIV-1trans-Activation-responsive RNA Element Form RNA-DNA Kissing Complexes* , 1999, The Journal of Biological Chemistry.
[23] D. Crothers,et al. The solution structure of an RNA loop-loop complex: the ColE1 inverted loop sequence. , 1998, Structure.
[24] J. Wengel,et al. Synthesis of Novel Bicyclo[2.2.1] Ribonucleosides: 2'-Amino- and 2'-Thio-LNA Monomeric Nucleosides. , 1998, The Journal of organic chemistry.
[25] I. Tinoco,et al. The structure of an RNA "kissing" hairpin complex of the HIV TAR hairpin loop and its complement. , 1997, Journal of molecular biology.
[26] J. Karn,et al. High affinity binding of TAR RNA by the human immunodeficiency virus type-1 tat protein requires base-pairs in the RNA stem and amino acid residues flanking the basic region. , 1993, Journal of molecular biology.
[27] J. Szostak,et al. In vitro selection of RNA molecules that bind specific ligands , 1990, Nature.
[28] L. Gold,et al. Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. , 1990, Science.
[29] S. Kauppinen,et al. Locked Nucleic Acid: High-Affinity Targeting of Complementary RNA for RNomics , 2006, Handbook of experimental pharmacology.
[30] C. Di Primo,et al. LNA/DNA chimeric oligomers mimic RNA aptamers targeted to the TAR RNA element of HIV-1. , 2004, Nucleic Acids Research.
[31] C. Di Primo,et al. Modulation of RNA function by oligonucleotides recognizing RNA structure. , 2001, Progress in nucleic acid research and molecular biology.
[32] J. Wengel,et al. The conformations of locked nucleic acids (LNA) , 2000, Journal of molecular recognition : JMR.