EGR2 induces apoptosis in various cancer cell lines by direct transactivation of BNIP3L and BAK

[1]  Yusuke Nakamura,et al.  Growth-suppressive effects of BPOZ and EGR2, two genes involved in the PTEN signaling pathway , 2001, Oncogene.

[2]  G. Evan,et al.  Caspase‐8 in Apoptosis: The Beginning of “The End”? , 2000, IUBMB life.

[3]  Yusuke Nakamura,et al.  AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1 , 2000, Nature Genetics.

[4]  Yusuke Nakamura,et al.  Bcl-2/E1B 19 kDa-interacting protein 3-like protein (Bnip3L) interacts with Bcl-2/Bcl-xL and induces apoptosis by altering mitochondrial membrane permeability , 1999, Oncogene.

[5]  J. Martinou.  Apoptosis: Key to the mitochondrial gate , 1999, Nature.

[6]  V. Dixit,et al.  Apoptosis control by death and decoy receptors. , 1999, Current opinion in cell biology.

[7]  J. Ashwell,et al.  Role of Egr-2 in Up-regulation of Fas Ligand in Normal T Cells and Aberrant Double-negative lpr and gld T Cells* , 1999, The Journal of Biological Chemistry.

[8]  Lianfa Shi,et al.  Nix and Nip3 Form a Subfamily of Pro-apoptotic Mitochondrial Proteins* , 1999, The Journal of Biological Chemistry.

[9]  E. Reddy,et al.  Modulation of life and death by the TNF receptor superfamily , 1998, Oncogene.

[10]  T. Mak,et al.  High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice , 1998, Current Biology.

[11]  J. Lupski,et al.  Mutations in the early growth response 2 (EGR2) gene are associated with hereditary myelinopathies , 1998, Nature Genetics.

[12]  T. Fujiwara,et al.  Isolation, mapping, and functional analysis of a novel human cDNA (BNIP3L) encoding a protein homologous to human NIP3 , 1998, Genes, chromosomes & cancer.

[13]  S. Srinivasula,et al.  Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade , 1997, Cell.

[14]  W. K. Alfred Yung,et al.  Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers , 1997, Nature Genetics.

[15]  M. Wigler,et al.  PTEN, a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer , 1997, Science.

[16]  R. Meadows,et al.  Structure of Bcl-xL-Bak Peptide Complex: Recognition Between Regulators of Apoptosis , 1997, Science.

[17]  S. Scherer,et al.  The Transcription Factors SCIP and Krox-20 Mark Distinct Stages and Cell Fates in Schwann Cell Differentiation , 1996, Molecular and Cellular Neuroscience.

[18]  D. MacEwan.  Elevated cPLA2 levels as a mechanism by which the p70 TNF and p75 NGF receptors enhance apoptosis , 1996, FEBS letters.

[19]  J. Martinou,et al.  Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K , 1995, Nature.

[20]  Matthew J. Brauer,et al.  Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak , 1995, Nature.

[21]  G. Evan,et al.  Induction of apoptosis by the Bcl-2 homologue Bak , 1995, Nature.

[22]  S. Korsmeyer,et al.  Bad, a heterodimeric partner for Bcl-xL and Bcl-2, displaces bax and promotes cell death , 1995, Cell.

[23]  S. Schneider-Maunoury,et al.  Krox-20 controls myelination in the peripheral nervous system , 1994, Nature.

[24]  L. Butcher,et al.  Induction of apoptosis by the low-affinity NGF receptor. , 1993, Science.

[25]  R. Krumlauf,et al.  The zinc finger gene Krox20 regulates HoxB2 (Hox2.8) during hindbrain segmentation , 1993, Cell.

[26]  R. Abramson,et al.  Detection of specific polymerase chain reaction product by utilizing the 5'----3' exonuclease activity of Thermus aquaticus DNA polymerase. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[27]  Toby J. Gibson,et al.  Base sequence discrimination by zinc-finger DNA-binding domains , 1991, Nature.

[28]  M. Vigneron,et al.  The segment‐specific gene Krox‐20 encodes a transcription factor with binding sites in the promoter region of the Hox‐1.4 gene. , 1990, The EMBO journal.

[29]  M. Zerial,et al.  A gene encoding a protein with zinc fingers is activated during G0/G1 transition in cultured cells. , 1988, The EMBO journal.