A Critical Review of Magnetic Resonance Spectroscopy Studies of Obsessive-Compulsive Disorder

[1]  C. Kucukali,et al.  Genetic variants in nuclear-encoded mitochondrial proteins are associated with oxidative stress in obsessive compulsive disorders. , 2012, Journal of psychiatric research.

[2]  Daniel Güllmar,et al.  White matter structure and symptom dimensions in obsessive-compulsive disorder. , 2012, Journal of psychiatric research.

[3]  J. Castro-Fornieles,et al.  Proton magnetic resonance spectroscopy in pediatric obsessive–compulsive disorder: Longitudinal study before and after treatment , 2012, Psychiatry Research: Neuroimaging.

[4]  S. Whiteside,et al.  The effect of behavior therapy on caudate N-acetyl-l-aspartic acid in adults with obsessive–compulsive disorder , 2012, Psychiatry Research: Neuroimaging.

[5]  N. Salamon,et al.  MRSI correlates of cognitive–behavioral therapy in pediatric obsessive–compulsive disorder , 2012, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[6]  C. Pittenger,et al.  Glutamate abnormalities in obsessive compulsive disorder: neurobiology, pathophysiology, and treatment. , 2011, Pharmacology & therapeutics.

[7]  Melissa Terpstra,et al.  Noninvasive quantification of ascorbate and glutathione concentration in the elderly human brain , 2011, NMR in biomedicine.

[8]  Ö. Ünal,et al.  The involvement of distinct neural systems in patients with obsessive–compulsive disorder with autogenous and reactive obsessions , 2011, Acta psychiatrica Scandinavica.

[9]  S. E. Stewart,et al.  Association Between Polymorphisms in GRIK2 Gene and Obsessive‐Compulsive Disorder: A Family‐Based Study , 2011, CNS neuroscience & therapeutics.

[10]  U. Ziemann,et al.  Combined 1H and 31P spectroscopy provides new insights into the pathobiochemistry of brain damage in multiple sclerosis , 2011, NMR in biomedicine.

[11]  Dan J Stein,et al.  Cortico-striatal oxidative status, dopamine turnover and relation with stereotypy in the deer mouse , 2011, Physiology & Behavior.

[12]  S. Chantal,et al.  Brain magnetic resonance spectroscopy in obsessive–compulsive disorder: The importance of considering subclinical symptoms of anxiety and depression , 2011, Psychiatry Research: Neuroimaging.

[13]  S. Rauch,et al.  Comprehensive family‐based association study of the glutamate transporter gene SLC1A1 in obsessive‐compulsive disorder , 2011, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[14]  Dost Öngür,et al.  Magnetic Resonance Spectroscopy Studies of Glutamate-Related Abnormalities in Mood Disorders , 2010, Biological Psychiatry.

[15]  Ke-min Chen,et al.  Increased N‐Acetylaspartate/creatine ratio in the medial prefrontal cortex among unmedicated obsessive–compulsive disorder patients , 2010, Psychiatry and clinical neurosciences.

[16]  Joaquim Radua,et al.  Meta-analytical comparison of voxel-based morphometry studies in obsessive-compulsive disorder vs other anxiety disorders. , 2010, Archives of general psychiatry.

[17]  Dost Öngür,et al.  Rapid Enhancement of Glutamatergic Neurotransmission in Bipolar Depression Following Treatment with Riluzole , 2010, Neuropsychopharmacology.

[18]  J. Raduà,et al.  Voxel-wise meta-analysis of grey matter changes in obsessive-compulsive disorder. , 2009, The British journal of psychiatry : the journal of mental science.

[19]  S. Rauch,et al.  A family‐based association study of the glutamate transporter gene SLC1A1 in obsessive–compulsive disorder in 378 families , 2009, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[20]  B. Devlin,et al.  Neural correlates of symptom dimensions in pediatric obsessive-compulsive disorder: a functional magnetic resonance imaging study. , 2009, Journal of the American Academy of Child and Adolescent Psychiatry.

[21]  M. Atmaca,et al.  Neurochemistry of the hippocampus in patients with obsessive–compulsive disorder , 2009, Psychiatry and clinical neurosciences.

[22]  Dost Öngür,et al.  Quantification of J‐resolved proton spectra in two‐dimensions with LCModel using GAMMA‐simulated basis sets at 4 Tesla , 2009, NMR in biomedicine.

[23]  D. Rosenberg,et al.  Glutamate receptor gene (GRIN2B) associated with reduced anterior cingulate glutamatergic concentration in pediatric obsessive–compulsive disorder , 2009, Psychiatry Research: Neuroimaging.

[24]  Dost Öngür,et al.  Creatine abnormalities in schizophrenia and bipolar disorder , 2009, Psychiatry Research: Neuroimaging.

[25]  D. Murphy,et al.  A haplotype containing quantitative trait loci for SLC1A1 gene expression and its association with obsessive-compulsive disorder. , 2009, Archives of general psychiatry.

[26]  B. Aouizerate,et al.  Meta-Analysis of Brain Volume Changes in Obsessive-Compulsive Disorder , 2009, Biological Psychiatry.

[27]  Guoping Feng,et al.  Glutamatergic Synaptic Dysfunction and Obsessive-Compulsive Disorder , 2008, Current chemical genomics.

[28]  M. Keshavan,et al.  Brain structure and symptom dimension relationships in obsessive-compulsive disorder: a voxel-based morphometry study. , 2008, Journal of affective disorders.

[29]  G. Starck,et al.  A 1H magnetic resonance spectroscopy study in adults with obsessive compulsive disorder: relationship between metabolite concentrations and symptom severity , 2008, Journal of Neural Transmission.

[30]  B. Harrison,et al.  Anterior Cingulate Glutamate–Glutamine Levels Predict Symptom Severity in Women With Obsessive–Compulsive Disorder , 2008, The Australian and New Zealand journal of psychiatry.

[31]  S. Selek,et al.  Oxidative imbalance in obsessive compulsive disorder patients: A total evaluation of oxidant–antioxidant status , 2008, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[32]  S. E. Stewart,et al.  Association of the SLC1A1 glutamate transporter gene and obsessive‐compulsive disorder , 2007, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[33]  Mark A Frye,et al.  Increased Anterior Cingulate/Medial Prefrontal Cortical Glutamate and Creatine in Bipolar Depression , 2007, Neuropsychopharmacology.

[34]  R. Robinson,et al.  In vivo proton magnetic resonance spectroscopy in patients with mood disorders: A technically oriented review , 2007, Journal of magnetic resonance imaging : JMRI.

[35]  Mari A. Smith,et al.  Proton magnetic resonance spectroscopy in obsessive-compulsive disorder: A pilot investigation comparing treatment responders and non-responders , 2007, Psychiatry Research: Neuroimaging.

[36]  J. Kwon,et al.  White matter abnormalities in drug‐naïve patients with obsessive–compulsive disorder: a Diffusion Tensor Study before and after citalopram treatment , 2007, Acta psychiatrica Scandinavica.

[37]  S. Dudek,et al.  Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice , 2007, Nature.

[38]  Dennis Velakoulis,et al.  Functional and biochemical alterations of the medial frontal cortex in obsessive-compulsive disorder. , 2007, Archives of general psychiatry.

[39]  Martin G Pomper,et al.  In vivo differentiation of N‐acetyl aspartyl glutamate from N‐acetyl aspartate at 3 Tesla , 2007, Magnetic resonance in medicine.

[40]  R. Delorme,et al.  A genetic family-based association study of OLIG2 in obsessive-compulsive disorder. , 2007, Archives of general psychiatry.

[41]  J. Moffett,et al.  N-Acetylaspartate in the CNS: From neurodiagnostics to neurobiology , 2007, Progress in Neurobiology.

[42]  T. Ohmori,et al.  Proton magnetic resonance spectroscopy reveals an abnormality in the anterior cingulate of a subgroup of obsessive–compulsive disorder patients , 2007, Psychiatry Research: Neuroimaging.

[43]  A. Nieoullon,et al.  The neuronal excitatory amino acid transporter EAAC1/EAAT3: does it represent a major actor at the brain excitatory synapse? , 2006, Journal of neurochemistry.

[44]  T. Someya,et al.  Parietal white matter abnormalities in obsessive–compulsive disorder: a magnetic resonance spectroscopy study at 3‐Tesla , 2006, Acta psychiatrica Scandinavica.

[45]  D. Dickel,et al.  Association testing of the positional and functional candidate gene SLC1A1/EAAC1 in early-onset obsessive-compulsive disorder. , 2006, Archives of general psychiatry.

[46]  J. Kennedy,et al.  Glutamate transporter gene SLC1A1 associated with obsessive-compulsive disorder. , 2006, Archives of general psychiatry.

[47]  J. Kwon,et al.  A proton MRSI study of brain N-acetylaspartate level after 12 weeks of citalopram treatment in drug-naive patients with obsessive-compulsive disorder. , 2006, American Journal of Psychiatry.

[48]  D. Ankerst,et al.  Review of 1H magnetic resonance spectroscopy findings in major depressive disorder: A meta-analysis , 2006, Psychiatry Research: Neuroimaging.

[49]  S. Whiteside,et al.  A magnetic resonance spectroscopy investigation of obsessive–compulsive disorder and anxiety , 2006, Psychiatry Research: Neuroimaging.

[50]  P. Renshaw,et al.  Increased Medial Thalamic Creatine-Phosphocreatine Found by Proton Magnetic Resonance Spectroscopy in Children With Obsessive-Compulsive Disorder Versus Major Depression and Healthy Controls , 2006, Journal of child neurology.

[51]  Blaise deB. Frederick,et al.  Grey and white matter GABA level differences in the human brain using two‐dimensional, J‐resolved spectroscopic imaging , 2005, NMR in biomedicine.

[52]  Manzar Ashtari,et al.  White matter abnormalities in obsessive-compulsive disorder: a diffusion tensor imaging study. , 2005, Archives of general psychiatry.

[53]  David Mataix-Cols,et al.  A multidimensional model of obsessive-compulsive disorder. , 2005, The American journal of psychiatry.

[54]  Dick J. Veltman,et al.  Amygdala activity in obsessive-compulsive disorder with contamination fear: a study with oxygen-15 water positron emission tomography , 2004, Psychiatry Research: Neuroimaging.

[55]  D. Rosenberg,et al.  Reduced anterior cingulate glutamatergic concentrations in childhood OCD and major depression versus healthy controls. , 2004, Journal of the American Academy of Child and Adolescent Psychiatry.

[56]  S. E. Stewart,et al.  Long‐term outcome of pediatric obsessive–compulsive disorder: a meta‐analysis and qualitative review of the literature , 2004, Acta psychiatrica Scandinavica.

[57]  M. Phillips,et al.  Distinct neural correlates of washing, checking, and hoarding symptom dimensions in obsessive-compulsive disorder. , 2004, Archives of general psychiatry.

[58]  H. Sackeim,et al.  Dorsolateral prefrontal cortical pathology in generalized anxiety disorder: a proton magnetic resonance spectroscopic imaging study. , 2004, The American journal of psychiatry.

[59]  D. Rosenberg,et al.  Association of a glutamate (NMDA) subunit receptor gene (GRIN2B) with obsessive-compulsive disorder: a preliminary study , 2004, Psychopharmacology.

[60]  D. Rosenberg,et al.  Increased medial thalamic choline found in pediatric patients with obsessive-compulsive disorder versus major depression or healthy control subjects: a magnetic resonance spectroscopy study , 2003, Biological Psychiatry.

[61]  D. Rosenberg,et al.  Neurochemical analyses in pediatric obsessive-compulsive disorder in patients treated with cognitive-behavioral therapy. , 2003, Journal of the American Academy of Child and Adolescent Psychiatry.

[62]  J. Kwon,et al.  Neural correlates of clinical symptoms and cognitive dysfunctions in obsessive–compulsive disorder , 2003, Psychiatry Research: Neuroimaging.

[63]  K. Kanamori,et al.  Glial uptake of neurotransmitter glutamate from the extracellular fluid studied in vivo by microdialysis and 13C NMR , 2002, Journal of neurochemistry.

[64]  Sung-Cheng Huang,et al.  Differential cerebral metabolic changes with paroxetine treatment of obsessive-compulsive disorder vs major depression. , 2002, Archives of general psychiatry.

[65]  J. Leckman,et al.  Adults with early-onset obsessive-compulsive disorder. , 2001, The American journal of psychiatry.

[66]  Jun Soo Kwon,et al.  Grey matter abnormalities in obsessive–compulsive disorder , 2001, British Journal of Psychiatry.

[67]  D. Rosenberg,et al.  Increased Medial Thalamic Choline in Pediatric Obsessive-Compulsive Disorder as Detected by Quantitative in Vivo Spectroscopic Imaging , 2001, Journal of child neurology.

[68]  D. Rosenberg,et al.  Case study: caudate glutamatergic changes with paroxetine persist after medication discontinuation in pediatric OCD. , 2001, Journal of the American Academy of Child and Adolescent Psychiatry.

[69]  M W Weiner,et al.  Region and tissue differences of metabolites in normally aged brain using multislice 1H magnetic resonance spectroscopic imaging , 2001, Magnetic resonance in medicine.

[70]  M. Keshavan,et al.  Decrease in caudate glutamatergic concentrations in pediatric obsessive-compulsive disorder patients taking paroxetine. , 2000, Journal of the American Academy of Child and Adolescent Psychiatry.

[71]  S. Rauch,et al.  Functional neuroimaging and the neuroanatomy of obsessive-compulsive disorder. , 2000, The Psychiatric clinics of North America.

[72]  S. Holland,et al.  fMRI of neuronal activation with symptom provocation in unmedicated patients with obsessive compulsive disorder. , 2000, Journal of psychiatric research.

[73]  V. Govindaraju,et al.  Proton NMR chemical shifts and coupling constants for brain metabolites , 2000, NMR in biomedicine.

[74]  D. Rosenberg,et al.  Proton spectroscopic imaging of the thalamus in treatment-naive pediatric obsessive–compulsive disorder∗ , 2000, Biological Psychiatry.

[75]  H. Isoda,et al.  Proton magnetic resonance spectroscopy of lenticular nuclei in obsessive–compulsive disorder , 1999, Psychiatry Research: Neuroimaging.

[76]  R W Neufeld,et al.  A short echo 1H spectroscopy and volumetric MRI study of the corpus striatum in patients with obsessive-compulsive disorder and comparison subjects. , 1998, The American journal of psychiatry.

[77]  R. Shulman,et al.  Functional Energy Metabolism:In vivo 13C-NMR Spectroscopy Evidence for Coupling of Cerebral Glucose Consumption and Gl utamatergic Neuronal Activity , 1998, Developmental Neuroscience.

[78]  D. Rosenberg,et al.  Case study: caudate glutamatergic changes with paroxetine therapy for pediatric obsessive-compulsive disorder. , 1998, Journal of the American Academy of Child and Adolescent Psychiatry.

[79]  J. Coyle.  The Nagging Question of the Function ofN-Acetylaspartylglutamate , 1997, Neurobiology of Disease.

[80]  J. Pierri,et al.  Frontostriatal measurement in treatment-naive children with obsessive-compulsive disorder. , 1997, Archives of general psychiatry.

[81]  O. Speck,et al.  1H-magnetic resonance spectroscopy in obsessive-compulsive disorder: evidence for neuronal loss in the cingulate gyrus and the right striatum , 1997, Psychiatry Research: Neuroimaging.

[82]  J. Frahm,et al.  Differential distribution of NAA and NAAG in human brain as determined by quantitative localized proton MRS , 1997, NMR in biomedicine.

[83]  J. R. Baker,et al.  Functional magnetic resonance imaging of symptom provocation in obsessive-compulsive disorder. , 1996, Archives of general psychiatry.

[84]  D J Jenden,et al.  In vivo 1H MRS choline: correlation with in vitro chemistry/histology. , 1996, Life sciences.

[85]  J. Coyle,et al.  N-Acetylaspartate in neuropsychiatric disorders , 1995, Progress in Neurobiology.

[86]  M Ashtari,et al.  Reduced caudate nucleus volume in obsessive-compulsive disorder. , 1995, Archives of general psychiatry.

[87]  G. Fein,et al.  Axonal injury and membrane alterations in Alzheimer's disease suggested by in vivo proton magnetic resonance spectroscopic imaging , 1994, Annals of neurology.

[88]  B. Rosen,et al.  Evidence for irnnairment of energy metabofism in vivo in Huntington's disease using localized 1H NMR spectroscopy , 1993, Neurology.

[89]  J. Mazziotta,et al.  Caudate glucose metabolic rate changes with both drug and behavior therapy for obsessive-compulsive disorder. , 1992, Archives of general psychiatry.

[90]  P Pietrini,et al.  Cerebral glucose metabolism in childhood-onset obsessive-compulsive disorder. Revisualization during pharmacotherapy. , 1992, Archives of general psychiatry.

[91]  P M Matthews,et al.  Proton magnetic resonance spectroscopic imaging for metabolic characterization of demyelinating plaques , 1992, Annals of neurology.

[92]  D. Murphy,et al.  Local cerebral glucose metabolic rates in obsessive-compulsive disorder. Patients treated with clomipramine. , 1990, Archives of general psychiatry.

[93]  J. Rapoport,et al.  Cerebral glucose metabolism in childhood-onset obsessive-compulsive disorder. , 1989, Archives of general psychiatry.

[94]  T. Nordahl,et al.  Cerebral glucose metabolic rates in obsessive compulsive disorder. , 1989, Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.

[95]  J. Mazziotta,et al.  Local cerebral glucose metabolic rates in obsessive-compulsive disorder. A comparison with rates in unipolar depression and in normal controls. , 1987, Archives of general psychiatry.

[96]  Dan J Stein,et al.  The epidemiology of obsessive-compulsive disorder in the National Comorbidity Survey Replication , 2010, Molecular Psychiatry.

[97]  Nikos Makris,et al.  A diffusion tensor imaging study of white matter in obsessive–compulsive disorder , 2007, Depression and anxiety.

[98]  R. Swanson,et al.  Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse , 2006, Nature Neuroscience.

[99]  M. Jenike.  Clinical practice. Obsessive-compulsive disorder. , 2004, The New England journal of medicine.

[100]  D. Rosenberg,et al.  Localized functional neurochemical marker abnormalities in dorsolateral prefrontal cortex in pediatric obsessive-compulsive disorder. , 2003, Journal of child and adolescent psychopharmacology.

[101]  N. Alpert,et al.  Regional cerebral blood flow measured during symptom provocation in obsessive-compulsive disorder using oxygen 15-labeled carbon dioxide and positron emission tomography. , 1994, Archives of general psychiatry.

[102]  B R Rosen,et al.  Evidence for impairment of energy metabolism in vivo in Huntington's disease using localized 1H NMR spectroscopy. , 1993, Neurology.