Tetramerization and DNA ligase IV interaction of the DNA double-strand break repair protein XRCC4 are mutually exclusive.
暂无分享,去创建一个
R. Ghirlando | Wei Yang | R. Kanaar | M. Gellert | M. Modesti | M. Junop | M. van de Rakt | M. W. van de Rakt
[1] P. Jeggo,et al. Identification of a DNA Nonhomologous End-Joining Complex in Bacteria , 2002, Science.
[2] D. Ramsden,et al. Association of DNA Polymerase μ (pol μ) with Ku and Ligase IV: Role for pol μ in End-Joining Double-Strand Break Repair , 2002, Molecular and Cellular Biology.
[3] S. West,et al. Involvement of human polynucleotide kinase in double‐strand break repair by non‐homologous end joining , 2002, The EMBO journal.
[4] M. Gellert. V(D)J recombination: RAG proteins, repair factors, and regulation. , 2002, Annual review of biochemistry.
[5] L. Chin,et al. Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions. , 2001, Molecular cell.
[6] B. L. Sibanda,et al. Crystal structure of an Xrcc4–DNA ligase IV complex , 2001, Nature Structural Biology.
[7] M. Gellert,et al. Intermediates in V(D)J recombination: A stable RAG1/2 complex sequesters cleaved RSS ends , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[8] A. Fischer,et al. Artemis, a Novel DNA Double-Strand Break Repair/V(D)J Recombination Protein, Is Mutated in Human Severe Combined Immune Deficiency , 2001, Cell.
[9] J. Hoeijmakers,et al. Chromosomal stability and the DNA double-stranded break connection , 2001, Nature Reviews Genetics.
[10] R. Ghirlando,et al. Crystal structure of the Xrcc4 DNA repair protein and implications for end joining , 2000, The EMBO journal.
[11] Kyung-Jong Lee,et al. DNA Ligase IV and XRCC4 Form a Stable Mixed Tetramer That Functions Synergistically with Other Repair Factors in a Cell-free End-joining System* , 2000, The Journal of Biological Chemistry.
[12] F. Alt,et al. Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development , 2000, Nature.
[13] S. Jackson,et al. Ku, a DNA repair protein with multiple cellular functions? , 1999, Mutation research.
[14] M. Gellert,et al. DNA binding of Xrcc4 protein is associated with V(D)J recombination but not with stimulation of DNA ligase IV activity , 1999, The EMBO journal.
[15] M. Lieber. The biochemistry and biological significance of nonhomologous DNA end joining: an essential repair process in multicellular eukaryotes , 1999, Genes to cells : devoted to molecular & cellular mechanisms.
[16] T. Stamato,et al. Absence of DNA ligase IV protein in XR-1 cells: evidence for stabilization by XRCC4. , 1999, Mutation research.
[17] D. Barnes,et al. Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice , 1998, Current Biology.
[18] F. Alt,et al. A Critical Role for DNA End-Joining Proteins in Both Lymphogenesis and Neurogenesis , 1998, Cell.
[19] F. Alt,et al. Late embryonic lethality and impaired V (D)J recombination in mice lacking DNA ligase IV , 1998, Nature.
[20] M. Sternberg,et al. Structure of an XRCC1 BRCT domain: a new protein–protein interaction module , 1998, The EMBO journal.
[21] K. Schwarz,et al. DNA ligase IV is essential for V(D)J recombination and DNA double-strand break repair in human precursor lymphocytes. , 1998, Molecular cell.
[22] S. Jackson,et al. DNA end-joining: from yeast to man. , 1998, Trends in biochemical sciences.
[23] M. Lieber,et al. Requirement for an Interaction of XRCC4 with DNA Ligase IV for Wild-type V(D)J Recombination and DNA Double-strand Break Repairin Vivo * , 1998, The Journal of Biological Chemistry.
[24] Y. Yamaguchi-Iwai,et al. Homologous recombination and non‐homologous end‐joining pathways of DNA double‐strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells , 1998, The EMBO journal.
[25] B. Wickstead,et al. Role of a BRCT domain in the interaction of DNA ligase III-α with the DNA repair protein XRCC1 , 1998, Current Biology.
[26] F. Alt,et al. Molecular genetic characterization of XRCC4 function. , 1997, International immunology.
[27] S. Jackson,et al. Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV , 1997, Current Biology.
[28] M. Lieber,et al. Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells , 1997, Nature.
[29] J. Hoeijmakers,et al. Disruption of Mouse RAD54 Reduces Ionizing Radiation Resistance and Homologous Recombination , 1997, Cell.
[30] D. Schatz,et al. RAG1 and RAG2 Form a Stable Postcleavage Synaptic Complex with DNA Containing Signal Ends in V(D)J Recombination , 1997, Cell.
[31] J. Mornon,et al. From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair , 1997, FEBS letters.
[32] T. Lindahl,et al. DNA Ligase IV from HeLa Cell Nuclei* , 1996, The Journal of Biological Chemistry.
[33] F. Alt,et al. The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination , 1995, Cell.
[34] D. Barnes,et al. Molecular cloning and expression of human cDNAs encoding a novel DNA ligase IV and DNA ligase III, an enzyme active in DNA repair and recombination , 1995, Molecular and cellular biology.
[35] J E Hesse,et al. Expression and V(D)J recombination activity of mutated RAG-1 proteins. , 1994, Nucleic acids research.
[36] F. Alt,et al. Impairment of V(D)J recombination in double-strand break repair mutants. , 1993, Science.
[37] J. Dixon,et al. Eukaryotic proteins expressed in Escherichia coli: an improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase. , 1991, Analytical biochemistry.
[38] Stephen J. Perkins,et al. Protein volumes and hydration effects , 1986 .
[39] A. Giaccia,et al. Isolation of cell cycle-dependent gamma ray-sensitive Chinese hamster ovary cell , 1983, Somatic cell genetics.