Induction of lipogenesis in white fat during cold exposure in mice: link to lean phenotype

[1]  P. Arner,et al.  An AMP-activated protein kinase–stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice , 2016, Nature Medicine.

[2]  D. Mutch,et al.  Reduced ATGL-mediated lipolysis attenuates β-adrenergic-induced AMPK signaling, but not the induction of PKA-targeted genes, in adipocytes and adipose tissue. , 2016, American journal of physiology. Cell physiology.

[3]  M. Cowley,et al.  A BAT-Centric Approach to the Treatment of Diabetes: Turn on the Brain. , 2016, Cell metabolism.

[4]  H. Rodewald,et al.  Of Mouse Models of Mast Cell Deficiency and Metabolic Syndrome. , 2016, Cell metabolism.

[5]  H. Sul,et al.  AMPK Phosphorylates Desnutrin/ATGL and Hormone-Sensitive Lipase To Regulate Lipolysis and Fatty Acid Oxidation within Adipose Tissue , 2016, Molecular and Cellular Biology.

[6]  R. Lecomte,et al.  Metabolic activity of brown, "beige," and white adipose tissues in response to chronic adrenergic stimulation in male mice. , 2016, American journal of physiology. Endocrinology and metabolism.

[7]  J. Kopecký,et al.  Early differences in metabolic flexibility between obesity-resistant and obesity-prone mice. , 2016, Biochimie.

[8]  S. Kersten,et al.  Brown adipose tissue takes up plasma triglycerides mostly after lipolysis , 2015, Journal of Lipid Research.

[9]  J. Horton,et al.  A high-fat diet suppresses de novo lipogenesis and desaturation but not elongation and triglyceride synthesis in mice[S] , 2014, Journal of Lipid Research.

[10]  J. Granneman,et al.  Coupling of lipolysis and de novo lipogenesis in brown, beige, and white adipose tissues during chronic β3-adrenergic receptor activation , 2014, Journal of Lipid Research.

[11]  J. Romijn,et al.  Sympathetic nervous system control of triglyceride metabolism: novel concepts derived from recent studies , 2014, Journal of Lipid Research.

[12]  P. Flachs,et al.  Stimulation of mitochondrial oxidative capacity in white fat independent of UCP1: a key to lean phenotype. , 2013, Biochimica et biophysica acta.

[13]  O. Muzik,et al.  15O PET Measurement of Blood Flow and Oxygen Consumption in Cold-Activated Human Brown Fat , 2013, The Journal of Nuclear Medicine.

[14]  M. Czech,et al.  Insulin signalling mechanisms for triacylglycerol storage , 2013, Diabetologia.

[15]  P. Flachs,et al.  Anti-obesity effect of n-3 polyunsaturated fatty acids in mice fed high-fat diet is independent of cold-induced thermogenesis. , 2013, Physiological research.

[16]  R. Gimeno,et al.  The breadth of FGF21's metabolic actions are governed by FGFR1 in adipose tissue. , 2013, Molecular metabolism.

[17]  Y. Hiraoka,et al.  Active involvement of micro-lipid droplets and lipid-droplet-associated proteins in hormone-stimulated lipolysis in adipocytes , 2012, Journal of Cell Science.

[18]  J. Granneman,et al.  Lipolytic Products Activate Peroxisome Proliferator-activated Receptor (PPAR) α and δ in Brown Adipocytes to Match Fatty Acid Oxidation with Supply* , 2012, The Journal of Biological Chemistry.

[19]  M. Blüher,et al.  A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism , 2012, Nature.

[20]  J. Timmons,et al.  Recruited vs. nonrecruited molecular signatures of brown, "brite," and white adipose tissues. , 2012, American journal of physiology. Endocrinology and metabolism.

[21]  P. Flachs,et al.  Synergistic induction of lipid catabolism and anti-inflammatory lipids in white fat of dietary obese mice in response to calorie restriction and n-3 fatty acids , 2011, Diabetologia.

[22]  F. Villarroya,et al.  Thermogenic Activation Induces FGF21 Expression and Release in Brown Adipose Tissue* , 2011, The Journal of Biological Chemistry.

[23]  Oliver T. Bruns,et al.  Brown adipose tissue activity controls triglyceride clearance , 2011, Nature Medicine.

[24]  G. Heldmaier,et al.  Adaptive thermogenesis and thermal conductance in wild-type and UCP1-KO mice. , 2010, American journal of physiology. Regulatory, integrative and comparative physiology.

[25]  Matej Oresic,et al.  Peroxisomal and Microsomal Lipid Pathways Associated with Resistance to Hepatic Steatosis and Reduced Pro-inflammatory State* , 2010, The Journal of Biological Chemistry.

[26]  Qing Yang,et al.  Fibroblast growth factor 21 regulates energy metabolism by activating the AMPK–SIRT1–PGC-1α pathway , 2010, Proceedings of the National Academy of Sciences.

[27]  L. Kozak Brown fat and the myth of diet-induced thermogenesis. , 2010, Cell metabolism.

[28]  Cyrus F. Khambatta,et al.  Calorie restriction increases fatty acid synthesis and whole body fat oxidation rates , 2010, American journal of physiology. Endocrinology and metabolism.

[29]  C. Dani,et al.  Contribution of Adipose Triglyceride Lipase and Hormone-sensitive Lipase to Lipolysis in hMADS Adipocytes* , 2009, The Journal of Biological Chemistry.

[30]  P. Flachs,et al.  n-3 Fatty acids and rosiglitazone improve insulin sensitivity through additive stimulatory effects on muscle glycogen synthesis in mice fed a high-fat diet , 2009, Diabetologia.

[31]  Stephen F Previs,et al.  Triglyceride Synthesis in Epididymal Adipose Tissue , 2009, Journal of Biological Chemistry.

[32]  Satoshi Haramizu,et al.  Different contribution of muscle and liver lipid metabolism to endurance capacity and obesity susceptibility of mice. , 2009, Journal of applied physiology.

[33]  S. Kalhan,et al.  Reassessing Triglyceride Synthesis in Adipose Tissue , 2022 .

[34]  Robert V Farese,et al.  Thematic review series: glycerolipids. DGAT enzymes and triacylglycerol biosynthesis. , 2008, Journal of lipid research.

[35]  E. Pastalkova,et al.  Induction of muscle thermogenesis by high-fat diet in mice: association with obesity-resistance. , 2008, American journal of physiology. Endocrinology and metabolism.

[36]  K. Rosenblatt,et al.  βKlotho is required for metabolic activity of fibroblast growth factor 21 , 2007, Proceedings of the National Academy of Sciences.

[37]  J. Ukropec,et al.  UCP1-independent Thermogenesis in White Adipose Tissue of Cold-acclimated Ucp1-/- Mice* , 2006, Journal of Biological Chemistry.

[38]  S. Cinti The adipose organ. , 2005, Prostaglandins, leukotrienes, and essential fatty acids.

[39]  E. Nisoli,et al.  Regional-dependent Increase of Sympathetic Innervation in Rat White Adipose Tissue during Prolonged Fasting , 2005, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[40]  J. Gromada,et al.  FGF-21 as a novel metabolic regulator. , 2005, The Journal of clinical investigation.

[41]  Frank Eisenhaber,et al.  Fat Mobilization in Adipose Tissue Is Promoted by Adipose Triglyceride Lipase , 2004, Science.

[42]  Jan Nedergaard,et al.  Brown adipose tissue: function and physiological significance. , 2004, Physiological reviews.

[43]  J. Granneman,et al.  White adipose tissue contributes to UCP1-independent thermogenesis. , 2003, American journal of physiology. Endocrinology and metabolism.

[44]  S. Tilghman,et al.  Glyceroneogenesis and the Triglyceride/Fatty Acid Cycle* , 2003, Journal of Biological Chemistry.

[45]  R. Hammer,et al.  Glyceroneogenesis comes of age , 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[46]  S. Tilghman,et al.  A mutation in the peroxisome proliferator-activated receptor γ-binding site in the gene for the cytosolic form of phosphoenolpyruvate carboxykinase reduces adipose tissue size and fat content in mice , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[47]  Thomas D. Schmittgen,et al.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.

[48]  P. Watson,et al.  Differential regulation of leptin expression and function in A/J vs. C57BL/6J mice during diet-induced obesity. , 2000, American journal of physiology. Endocrinology and metabolism.

[49]  K. Walsh,et al.  Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity. , 1998, The Journal of clinical investigation.

[50]  Y. Deshaies,et al.  β-Adrenergic modulation of triglyceridemia under increased energy expenditure. , 1998, American journal of physiology. Regulatory, integrative and comparative physiology.

[51]  B. Lowell,et al.  β3-Adrenergic Receptors on White and Brown Adipocytes Mediate β3-Selective Agonist-induced Effects on Energy Expenditure, Insulin Secretion, and Food Intake , 1997, The Journal of Biological Chemistry.

[52]  R. Surwit,et al.  Strain-Specific Response toβ 3-Adrenergic Receptor Agonist Treatment of Diet-Induced Obesity in Mice1. , 1997, Endocrinology.

[53]  I. Kettelhut,et al.  Effect of acute cold exposure on norepinephrine turnover rates in rat white adipose tissue. , 1996, Journal of the autonomic nervous system.

[54]  P. Trayhurn,et al.  Acute cold-induced suppression of ob (obese) gene expression in white adipose tissue of mice: mediation by the sympathetic system. , 1995, The Biochemical journal.

[55]  J. Kinney,et al.  Effect of carbohydrate intake on de novo lipogenesis in human adipose tissue. , 1987, The American journal of physiology.

[56]  P. Trayhurn Fatty acid synthesis in mouse brown adipose tissue. The influence of environmental temperature on the proportion of whole-body fatty acid synthesis in brown adipose tissue and the liver. , 1981, Biochimica et biophysica acta.

[57]  P. Trayhurn Fatty acid synthesis in vivo in brown adipose tissue, liver and white adipose tissue of the cold‐acclimated rat , 1979, FEBS letters.

[58]  L. Landsberg,et al.  Effect of diet and cold exposure on norepinephrine turnover in pancreas and liver. , 1979, The American journal of physiology.

[59]  M. Frydman,et al.  Nonshivering thermogenesis in the rat. II. Measurements of blood flow with microspheres point to brown adipose tissue as the dominant site of the calorigenesis induced by noradrenaline. , 1978, Canadian journal of physiology and pharmacology.

[60]  Newsholme Ea,et al.  Substrate cycles: their metabolic, energetic and thermic consequences in man. , 1978 .

[61]  P. Björntorp,et al.  Effects of glucose infusions on adipose tissue lipogenesis in man. , 2009, Acta medica Scandinavica.