Brachytherapy Seed Localization from Fluoroscopic Images Using a Statistical Classifier

A method to determine the number and location of seed images in clusters on a fluoroscopic image was developed based on a statistical analysis of cluster size in simulated fluoroscopic images. A modified 3-film technique was used to reconstruct the 3D positions of seeds from their image locations. Preliminary results suggest that this new method can identify all the seeds and localize them to an average precision of 0.55 mm. This is an important step toward intraoperative radiation dose analysis.