论文信息 - Synthesis and antimicrobialactivity of 2‐alkylcarbamato‐2,3‐dihydro‐5‐propylthio‐1H‐1,3,2‐benzodiazaphosphole 2‐oxides

Synthesis and antimicrobialactivity of 2‐alkylcarbamato‐2,3‐dihydro‐5‐propylthio‐1H‐1,3,2‐benzodiazaphosphole 2‐oxides

Novel 2-alkylcarbamato/thiocarbama-to-2,3-dihydro-5-propylthio-1H-1,3,2-benzodiazaphos-phole 2-oxides (4a–J) were synthesized by cyclization of 4-propylthio-1,2-phenylenediamine (3) with the corresponding dichlorophosphoryl carbamates/thiocarbamates (2a–J) that were obtained by the addition of alcohols/thiols to isocyanatophosphoryl dichloride (1). The structures of the title compounds were confirmed by the 1H, 13C, 31P NMR, and mass spectral studies. Some of these products were found to possess significant antimicrobial activity. © 2000 John Wiley & Sons, Inc. Heteroatom Chem 11:336–340, 2000

D. Srinivasulu | C. D. Reddy | B. S. Reddy

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