Hydrogenolyse von Trimethylsilylenolethern unter Verwendung eines sauren Rutheniumdiwasserstoff‐Komplexes als Katalysator

Die heterolytische Spaltung von H2ist der Schlusselschritt in der durch [RuCl(η2-H2)(dppe)2]OTf (dppe=1,2-Bis(diphenylphosphanyl)ethan, OTf=Trifluormethansulfonat) katalysierten Hydrogenolyse von Trimethylsilylenolethern, bei der ein Keton und Me3SiH die Produkte sind (siehe Schema). Die ebenfalls beschriebene stochiometrische, Ruthenium-unterstutzte Protonierung eines prochiralen Lithiumenolats mit H2 liefert hochenantioselektiv das chirale Keton (bis 75% ee).

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