Differentially Regulated by IL-18 and IL-12 Effector T Cells Is + Development of CD 8

[1]  Stephen P. Schoenberger,et al.  T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions , 1998, Nature.

[2]  Polly Matzinger,et al.  A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell , 1998, Nature.

[3]  Richard A. Flavell,et al.  Help for cytotoxic-T-cell responses is mediated by CD40 signalling , 1998, Nature.

[4]  L. Moretta,et al.  IL‐12‐induced up‐regulation of NKRP1A expression in human NK cells and consequent NKRP1A‐ mediated down‐regulation of NK cell activation , 1998, European journal of immunology.

[5]  H. Okamura,et al.  Differential capacities of CD4+, CD8+, and CD4-CD8- T cell subsets to express IL-18 receptor and produce IFN-gamma in response to IL-18. , 1998, Journal of immunology.

[6]  L. Moretta,et al.  Regulation of KIR expression in human T cells: a safety mechanism that may impair protective T-cell responses. , 1998, Immunology today.

[7]  G. Trinchieri,et al.  Recombinant interleukin 12 enhances cellular immune responses to vaccination only after a period of suppression. , 1998, Cancer research.

[8]  H. Cantor,et al.  Suppression of immune responses by CD8 cells. I. Superantigen-activated CD8 cells induce unidirectional Fas-mediated apoptosis of antigen-activated CD4 cells. , 1998, Journal of immunology.

[9]  R. Kastelein,et al.  IGIF Does Not Drive Th1 Development but Synergizes with IL-12 for Interferon-γ Production and Activates IRAK and NFκB , 1997 .

[10]  H. Okamura,et al.  A mechanism underlying synergy between IL-12 and IFN-gamma-inducing factor in enhanced production of IFN-gamma. , 1997, Journal of immunology.

[11]  A. Enk,et al.  Production of IL-18 (IFN-gamma-inducing factor) messenger RNA and functional protein by murine keratinocytes. , 1997, Journal of immunology.

[12]  M Kurimoto,et al.  IFN-gamma-inducing factor (IGIF) is a costimulatory factor on the activation of Th1 but not Th2 cells and exerts its effect independently of IL-12. , 1997, Journal of immunology.

[13]  A. Fauci,et al.  Human CD8+ T lymphocyte subsets that express HLA class I-specific inhibitory receptors represent oligoclonally or monoclonally expanded cell populations. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[14]  H. Hengartner,et al.  Different roles for cytotoxic T cells in the control of infections with cytopathic versus noncytopathic viruses. , 1996, Current opinion in immunology.

[15]  T. Tanimoto,et al.  Interferon‐γ‐inducing factor enhances T helper 1 cytokine production by stimulated human T cells: synergism with interleukin‐12 for interferon‐γ production , 1996 .

[16]  H. Okamura,et al.  Cloning of the cDNA for human IFN-gamma-inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein. , 1996, Journal of immunology.

[17]  T. Ohtsuki,et al.  Regulation of cytokine production by sugi allergen-pullulan conjugate. , 1996, Cellular immunology.

[18]  H. Okamura,et al.  Cloning of a new cytokine that induces IFN-γ production by T cells , 1995, Nature.

[19]  R. Dutton,et al.  Relative perforin- and Fas-mediated lysis in T1 and T2 CD8 effector populations. , 1995, Journal of immunology.

[20]  Yao-Tseng Chen,et al.  Influence of interleukin 12 on p53 peptide vaccination against established Meth A sarcoma. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[21]  T. Mosmann,et al.  Cytokine-induced differentiation of precursor mouse CD8+ T cells into cytotoxic CD8+ T cells secreting Th1 or Th2 cytokines. , 1995, Immunity.

[22]  G. Trinchieri,et al.  CD4 T cells inhibit in vivo the CD8‐mediated immune response against murine colon carcinoma cells transduced with interleukin‐12 genes , 1995, European journal of immunology.

[23]  G. Trinchieri,et al.  Interleukin 12 induces the differentiation of major histocompatibility complex class I-primed cytotoxic T-lymphocyte precursors into allospecific cytotoxic effectors. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[24]  M. Hirokawa,et al.  The role of transforming growth factor beta in the generation of suppression: an interaction between CD8+ T and NK cells , 1994, The Journal of experimental medicine.

[25]  M. Croft,et al.  Generation of polarized antigen-specific CD8 effector populations: reciprocal action of interleukin (IL)-4 and IL-12 in promoting type 2 versus type 1 cytokine profiles , 1994, The Journal of experimental medicine.

[26]  P. Henkart Lymphocyte-mediated cytotoxicity: two pathways and multiple effector molecules. , 1994, Immunity.

[27]  T. Inoue,et al.  Second signal activity of IL-12 on the proliferation and IL-2R expression of T helper cell-1 clone. , 1994, Journal of immunology.

[28]  J. Horváth,et al.  Cellular and molecular mechanisms of the IL-12-induced increase in allospecific murine cytolytic T cell activity. Implications for the age-related decline in CTL. , 1994, Journal of immunology.

[29]  P. Srivastava,et al.  Cellular requirements for tumor-specific immunity elicited by heat shock proteins: tumor rejection antigen gp96 primes CD8+ T cells in vivo. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[30]  H. Auchincloss,et al.  Indirect recognition by helper cells can induce donor-specific cytotoxic T lymphocytes in vivo , 1994, The Journal of experimental medicine.

[31]  J. Orange,et al.  Effects of IL-12 on the response and susceptibility to experimental viral infections. , 1994, Journal of immunology.

[32]  J. Siegel,et al.  Effects of IL-12 on the generation of cytotoxic activity in human CD8+ T lymphocytes. , 1993, Journal of immunology.

[33]  Susanne A. Fischer,et al.  Interleukin‐12/T cell stimulating factor, a cytokine with multiple effects on T helper type 1 (Th1) but not on Th2 cells , 1993, European journal of immunology.

[34]  C. Hsieh,et al.  Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages. , 1993, Science.

[35]  E. Maraskovsky,et al.  IL-2 and IFN-gamma are two necessary lymphokines in the development of cytolytic T cells. , 1989, Journal of immunology.

[36]  S. Landolfo,et al.  Monoclonal antibody against IFN-gamma inhibits Moloney murine sarcoma virus-specific cytotoxic T lymphocyte differentiation. , 1988, Journal of immunology.

[37]  G. Shearer,et al.  Role of cytotoxic T lymphocytes in the prevention of lupus-like disease occurring in a murine model of graft-vs-host disease. , 1987, Journal of immunology.

[38]  S. Pals,et al.  Graft-versus-host reactions: clues to the etiopathology of a spectrum of immunological diseases. , 1984, Immunology today.

[39]  J. Forman,et al.  Helper activity is required for the in vivo generation of cytotoxic T lymphocytes , 1982, The Journal of experimental medicine.

[40]  L. Pilarski A requirement for antigen-specific helper T cells in the generation of cytotoxic T cells from thymocyte precursors , 1977, The Journal of experimental medicine.

[41]  G. Shearer,et al.  T-cell interactions in autoimmunity: insights from a murine model of graft-versus-host disease. , 1988, Immunology today.

[42]  F. Bach,et al.  Interferon: a cytotoxic T lymphocyte differentiation signal , 1986, European journal of immunology.