Proteolytic Activity is Increased in Lymphocytes from Patients with Alzheimer’s Disease

[1]  Philip W. Landfield,et al.  Increase in Single L-Type Calcium Channels in Hippocampal Neurons During Aging , 1996, Science.

[2]  M. Alberoni,et al.  Erythrocytic calpain-calpastatin system in Alzheimer’s disease , 1996, Aging.

[3]  K. Blomgren,et al.  Increased proteolytic activity in lymphocytes from patients with early onset Alzheimer's disease , 1995, Neurobiology of Aging.

[4]  A. Martínez-Serrano,et al.  Altered cell calcium regulation in synaptosomes and brain cells of the 30-month-old rat: Prominent effects in hippocampus , 1995, Neurobiology of Aging.

[5]  E. Melloni,et al.  Reversible inactivation of calpain isoforms by nitric oxide. , 1995, Biochemical and biophysical research communications.

[6]  R. Scott,et al.  Alzheimer's disease and down syndrome: leukocyte membrane fluidity alterations , 1994, Mechanisms of Ageing and Development.

[7]  R. Nixon,et al.  Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer disease: a potential molecular basis for neuronal degeneration. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[8]  E. Mignot,et al.  Platelet cytosolic free-calcium concentration is increased in aging and Alzheimer's disease , 1993, Biological Psychiatry.

[9]  E. Villacres,et al.  Intracellular calcium response is reduced in CD4+ lymphocytes in Alzheimer's disease and in older persons with down's syndrome , 1993, Neurobiology of Aging.

[10]  C. Peterson Changes in Calcium's Role As a Messenger during Aging in Neuronal and Nonneuronal Cells a , 1992, Annals of the New York Academy of Sciences.

[11]  P. Whitehouse,et al.  Intracellular membranes are more fluid in platelets of Alzheimer's disease patients , 1991, Neurobiology of Aging.

[12]  A. Adunsky,et al.  Increased cytosolic free calcium in lymphocytes of Alzheimer patients , 1991, Journal of Neuroimmunology.

[13]  G. Bosman,et al.  Erythrocyte membrane characteristics indicate abnormal cellular aging in patients with Alzheimer's disease , 1991, Neurobiology of Aging.

[14]  G. Lynch,et al.  Increased spectrin proteolysis in fibroblasts from aged and Alzheimer donors , 1991, Neuroscience Letters.

[15]  K. Blomgren,et al.  Calpain and calpastatin in normal and Alzheimer-degenerated human brain tissue , 1990, Neurobiology of Aging.

[16]  R. Levy,et al.  Platelet and erythrocyte membrane changes in Alzheimer's disease. , 1990, Biochimica et biophysica acta.

[17]  E. Hogan,et al.  Ganglioside‐Modulated Proteolysis by Ca2+‐Activated Neutral Proteinase (CANP): A Role of Glycoconjugates in CANP Regulation , 1990, Journal of neurochemistry.

[18]  F. Di Lisa,et al.  Isovalerylcarnitine is a specific activator of the high calcium requiring calpain forms. , 1990, Biochemical and biophysical research communications.

[19]  K. Suzuki,et al.  Calcium activated neutral protease--structure-function relationship and functional implications. , 1990, Cell structure and function.

[20]  T. A. Pitler,et al.  Prolonged Ca2+-dependent afterhyperpolarizations in hippocampal neurons of aged rats. , 1984, Science.

[21]  D. Blumenthal,et al.  Identification and partial purification of a factor that stimulates calcium-dependent proteases. , 1982, Biochemistry.

[22]  L. Adam,et al.  Identification of a latent Ca2+/calmodulin dependent protein kinase II phosphorylation site in vascular calpain II. , 1994, Journal of biochemistry.