Cohesin, a chromatin engagement ring.

[1]  M. Bermudez-lopez,et al.  A SUMO-Dependent Step during Establishment of Sister Chromatid Cohesion , 2012, Current Biology.

[2]  A. Jarmuz,et al.  SUMOylation of the α-Kleisin Subunit of Cohesin Is Required for DNA Damage-Induced Cohesion , 2012, Current Biology.

[3]  Gabriele Gillessen-Kaesbach,et al.  HDAC8 mutations in Cornelia de Lange Syndrome affect the cohesin acetylation cycle , 2012, Nature.

[4]  Hongtao Yu,et al.  Scc1 sumoylation by Mms21 promotes sister chromatid recombination through counteracting Wapl. , 2012, Genes & development.

[5]  J. Javerzat,et al.  Pds5 promotes cohesin acetylation and stable cohesin–chromosome interaction , 2012, EMBO reports.

[6]  A. Pendás,et al.  Shugoshins: from protectors of cohesion to versatile adaptors at the centromere. , 2012, Trends in genetics : TIG.

[7]  E. de Álava,et al.  Meiotic cohesin complexes are essential for the formation of the axial element in mice , 2012, The Journal of cell biology.

[8]  D. Pisano,et al.  The specific contributions of cohesin-SA1 to cohesion and gene expression , 2012, Cell cycle.

[9]  I. Krantz,et al.  RAD21 mutations cause a human cohesinopathy. , 2012, American journal of human genetics.

[10]  K. Shirahige,et al.  The Prereplication Complex Recruits XEco2 to Chromatin to Promote Cohesin Acetylation in Xenopus Egg Extracts , 2012, Current Biology.

[11]  R. Jessberger Age‐related aneuploidy through cohesion exhaustion , 2012, EMBO reports.

[12]  M. Blasco,et al.  Cohesin‐SA1 deficiency drives aneuploidy and tumourigenesis in mice due to impaired replication of telomeres , 2012, The EMBO journal.

[13]  D. Pisano,et al.  A unique role of cohesin‐SA1 in gene regulation and development , 2012, The EMBO journal.

[14]  A. Ashworth,et al.  APRIN is a cell cycle specific BRCA2‐interacting protein required for genome integrity and a predictor of outcome after chemotherapy in breast cancer , 2012, The EMBO journal.

[15]  M. Torres-Padilla,et al.  Control of ground-state pluripotency by allelic regulation of Nanog , 2012, Nature.

[16]  Raymond K. Auerbach,et al.  Extensive Promoter-Centered Chromatin Interactions Provide a Topological Basis for Transcription Regulation , 2012, Cell.

[17]  G. Legube,et al.  Cohesin Protects Genes against γH2AX Induced by DNA Double-Strand Breaks , 2012, PLoS genetics.

[18]  G. Eichele,et al.  Cohesin acetyltransferase Esco2 is a cell viability factor and is required for cohesion in pericentric heterochromatin , 2011, The EMBO journal.

[19]  R. Skibbens Sticking a fork in cohesin--it's not done yet! , 2011, Trends in genetics : TIG.

[20]  D. Dorsett,et al.  Cohesin Selectively Binds and Regulates Genes with Paused RNA Polymerase , 2011, Current Biology.

[21]  K. Nasmyth,et al.  Cohesin's Concatenation of Sister DNAs Maintains Their Intertwining , 2011, Molecular cell.

[22]  K. Nasmyth Cohesin: a catenase with separate entry and exit gates? , 2011, Nature Cell Biology.

[23]  A. Lander,et al.  Multifactorial Origins of Heart and Gut Defects in nipbl-Deficient Zebrafish, a Model of Cornelia de Lange Syndrome , 2011, PLoS biology.

[24]  C. Barroso,et al.  Loading of Meiotic Cohesin by SCC-2 Is Required for Early Processing of DSBs and for the DNA Damage Checkpoint , 2011, Current Biology.

[25]  W. Taylor,et al.  Regulation of sororin by Cdk1-mediated phosphorylation , 2011, Journal of Cell Science.

[26]  Hongtao Yu,et al.  Mutational Inactivation of STAG2 Causes Aneuploidy in Human Cancer , 2011, Science.

[27]  D. Schatz,et al.  A role for cohesin in T cell receptor rearrangement and thymocyte differentiation , 2011, Nature.

[28]  K. Shirahige,et al.  Spo11-Accessory Proteins Link Double-Strand Break Sites to the Chromosome Axis in Early Meiotic Recombination , 2011, Cell.

[29]  L. Schöckel,et al.  Cleavage of cohesin rings coordinates the separation of centrioles and chromatids , 2011, Nature Cell Biology.

[30]  J. R. Daum,et al.  Cohesion Fatigue Induces Chromatid Separation in Cells Delayed at Metaphase , 2011, Current Biology.

[31]  Hong-Guo Yu,et al.  Scc2 regulates gene expression by recruiting cohesin to the chromosome as a transcriptional activator during yeast meiosis , 2011, Molecular biology of the cell.

[32]  A. Egashira,et al.  Double-Strand Break Repair-Independent Role for BRCA2 in Blocking Stalled Replication Fork Degradation by MRE11 , 2011, Cell.

[33]  C. Print,et al.  A Zebrafish Model of Roberts Syndrome Reveals That Esco2 Depletion Interferes with Development by Disrupting the Cell Cycle , 2011, PloS one.

[34]  Nicholas J. Schork,et al.  CCCTC-binding factor (CTCF) and cohesin influence the genomic architecture of the Igh locus and antisense transcription in pro-B cells , 2011, Proceedings of the National Academy of Sciences.

[35]  Nicholas A. Lyons,et al.  Cdk1-dependent destruction of Eco1 prevents cohesion establishment after S phase. , 2011, Molecular cell.

[36]  Y. Kim,et al.  Conserved, developmentally regulated mechanism couples chromosomal looping and heterochromatin barrier activity at the homeobox gene A locus , 2011, Proceedings of the National Academy of Sciences.

[37]  D. Dorsett Cohesin: genomic insights into controlling gene transcription and development. , 2011, Current opinion in genetics & development.

[38]  M. McKay,et al.  Can corruption of chromosome cohesion create a conduit to cancer? , 2011, Nature Reviews Cancer.

[39]  M. Groudine,et al.  Cohesin Mediates Chromatin Interactions That Regulate Mammalian β-globin Expression* , 2011, The Journal of Biological Chemistry.

[40]  R. Paro,et al.  Polycomb purification by in vivo biotinylation tagging reveals cohesin and Trithorax group proteins as interaction partners , 2011, Proceedings of the National Academy of Sciences.

[41]  F. Uhlmann,et al.  Cohesin loading and sliding , 2011, Journal of Cell Science.

[42]  J. Javerzat,et al.  Psm3 Acetylation on Conserved Lysine Residues Is Dispensable for Viability in Fission Yeast but Contributes to Eso1-Mediated Sister Chromatid Cohesion by Antagonizing Wpl1 , 2011, Molecular and Cellular Biology.

[43]  K. Nasmyth,et al.  ATP Hydrolysis Is Required for Relocating Cohesin from Sites Occupied by Its Scc2/4 Loading Complex , 2011, Current Biology.

[44]  K. Nasmyth,et al.  A positively charged channel within the Smc1/Smc3 hinge required for sister chromatid cohesion , 2010, The EMBO journal.

[45]  P. Jallepalli,et al.  Sister acts: coordinating DNA replication and cohesion establishment. , 2010, Genes & development.

[46]  Daniel Rico,et al.  Cohesin organizes chromatin loops at DNA replication factories. , 2010, Genes & development.

[47]  A. Hyman,et al.  Sororin Mediates Sister Chromatid Cohesion by Antagonizing Wapl , 2010, Cell.

[48]  Jian-hua Song,et al.  Sororin cooperates with the acetyltransferase Eco2 to ensure DNA replication-dependent sister chromatid cohesion , 2010, Proceedings of the National Academy of Sciences.

[49]  Helen R. Flynn,et al.  Hos1 deacetylates Smc3 to close the cohesin acetylation cycle. , 2010, Molecular cell.

[50]  K. Nasmyth,et al.  An Smc3 acetylation cycle is essential for establishment of sister chromatid cohesion. , 2010, Molecular cell.

[51]  Kathryn E. Crosier,et al.  Positive regulation of c-Myc by cohesin is direct, and evolutionarily conserved. , 2010, Developmental biology.

[52]  J. Malaterre,et al.  Rad21-Cohesin Haploinsufficiency Impedes DNA Repair and Enhances Gastrointestinal Radiosensitivity in Mice , 2010, PloS one.

[53]  D. Dorsett,et al.  Dosage-Sensitive Regulation of Cohesin Chromosome Binding and Dynamics by Nipped-B, Pds5, and Wapl , 2010, Molecular and Cellular Biology.

[54]  D. Koshland,et al.  Genetic Evidence that the Acetylation of the Smc3p Subunit of Cohesin Modulates Its ATP-Bound State to Promote Cohesion Establishment in Saccharomyces cerevisiae , 2010, Genetics.

[55]  David A. Orlando,et al.  Mediator and Cohesin Connect Gene Expression and Chromatin Architecture , 2010, Nature.

[56]  D. Gordenin,et al.  Cohesin Is Limiting for the Suppression of DNA Damage–Induced Recombination between Homologous Chromosomes , 2010, PLoS genetics.

[57]  Xuewen Pan,et al.  Genome-wide Reinforcement of Cohesin Binding at Pre-existing Cohesin Sites in Response to Ionizing Radiation in Human Cells* , 2010, The Journal of Biological Chemistry.

[58]  V. Guacci,et al.  Systematic Reduction of Cohesin Differentially Affects Chromosome Segregation, Condensation, and DNA Repair , 2010, Current Biology.

[59]  L. Ström,et al.  S-phase and DNA damage activated establishment of sister chromatid cohesion--importance for DNA repair. , 2010, Experimental cell research.

[60]  D. J. Clarke,et al.  Rad21 is required for centrosome integrity in human cells independently of its role in chromosome cohesion. , 2010, Cell cycle.

[61]  T. Hirano,et al.  Sister chromatid resolution: a cohesin releasing network and beyond , 2010, Chromosoma.

[62]  Petra C. Schwalie,et al.  A CTCF-independent role for cohesin in tissue-specific transcription. , 2010, Genome research.

[63]  Marco Foiani,et al.  Maintaining genome stability at the replication fork , 2010, Nature Reviews Molecular Cell Biology.

[64]  Ryan Dale,et al.  Cell type specificity of chromatin organization mediated by CTCF and cohesin , 2010, Proceedings of the National Academy of Sciences.

[65]  R. Gordân,et al.  Drosophila ORC localizes to open chromatin and marks sites of cohesin complex loading. , 2010, Genome research.

[66]  Ilan Davis,et al.  Cohesin cleavage and Cdk inhibition trigger formation of daughter nuclei , 2010, Nature Cell Biology.

[67]  Kim Nasmyth,et al.  Cohesin: its roles and mechanisms. , 2009, Annual review of genetics.

[68]  P. Jallepalli,et al.  Cohesin acetylation speeds the replication fork , 2009, Nature.

[69]  Susan Smith,et al.  Differential regulation of telomere and centromere cohesion by the Scc3 homologues SA1 and SA2, respectively, in human cells , 2009, The Journal of cell biology.

[70]  T. Hirano,et al.  Releasing cohesin from chromosome arms in early mitosis: opposing actions of Wapl-Pds5 and Sgo1. , 2009, Genes & development.

[71]  J. Peters,et al.  The cohesin complex is required for the DNA damage‐induced G2/M checkpoint in mammalian cells , 2009, The EMBO journal.

[72]  B. Hallgrímsson,et al.  Multiple Organ System Defects and Transcriptional Dysregulation in the Nipbl +/− Mouse, a Model of Cornelia de Lange Syndrome , 2009, PLoS genetics.

[73]  C. Schildkraut,et al.  Mammalian Telomeres Resemble Fragile Sites and Require TRF1 for Efficient Replication , 2009, Cell.

[74]  I. Krantz,et al.  Dosage Effects of Cohesin Regulatory Factor PDS5 on Mammalian Development: Implications for Cohesinopathies , 2009, PloS one.

[75]  Zhe Zhang,et al.  Transcriptional Dysregulation in NIPBL and Cohesin Mutant Human Cells , 2009, PLoS biology.

[76]  Karl Mechtler,et al.  Building sister chromatid cohesion: smc3 acetylation counteracts an antiestablishment activity. , 2009, Molecular cell.

[77]  T. Itoh,et al.  Budding Yeast Wpl1(Rad61)-Pds5 Complex Counteracts Sister Chromatid Cohesion-Establishing Reaction , 2009, Current Biology.

[78]  V. Guacci,et al.  Sister chromatid cohesion: a simple concept with a complex reality. , 2008, Annual review of cell and developmental biology.

[79]  Steven P. Gygi,et al.  A Molecular Determinant for the Establishment of Sister Chromatid Cohesion , 2008, Science.

[80]  Philip East,et al.  Eco1-Dependent Cohesin Acetylation During Establishment of Sister Chromatid Cohesion , 2008, Science.

[81]  J. Hurwitz,et al.  Cdc7-Drf1 kinase links chromosome cohesion to the initiation of DNA replication in Xenopus egg extracts. , 2008, Genes & development.

[82]  Xuewen Pan,et al.  Acetylation of Smc3 by Eco1 is required for S phase sister chromatid cohesion in both human and yeast. , 2008, Molecular cell.

[83]  H. Aburatani,et al.  Cohesin mediates transcriptional insulation by CCCTC-binding factor , 2008, Nature.

[84]  C. K. Schmidt,et al.  Cell‐cycle regulation of cohesin stability along fission yeast chromosomes , 2008, The EMBO journal.

[85]  Michael B. Eisen,et al.  Association of cohesin and Nipped-B with transcriptionally active regions of the Drosophila melanogaster genome , 2008, Chromosoma.

[86]  M. Speicher,et al.  Persistence of DNA threads in human anaphase cells suggests late completion of sister chromatid decatenation , 2007, Chromosoma.

[87]  J. Milbrandt,et al.  Mice lacking sister chromatid cohesion protein PDS5B exhibit developmental abnormalities reminiscent of Cornelia de Lange syndrome , 2007, Development.

[88]  Karl Mechtler,et al.  Sororin Is Required for Stable Binding of Cohesin to Chromatin and for Sister Chromatid Cohesion in Interphase , 2007, Current Biology.

[89]  D. Koshland,et al.  A Multi-Step Pathway for the Establishment of Sister Chromatid Cohesion , 2006, PLoS genetics.

[90]  T. Hirano,et al.  Human Wapl Is a Cohesin-Binding Protein that Promotes Sister-Chromatid Resolution in Mitotic Prophase , 2006, Current Biology.

[91]  J. Peters,et al.  Wapl Controls the Dynamic Association of Cohesin with Chromatin , 2006, Cell.

[92]  K. Nasmyth,et al.  Evidence that Loading of Cohesin Onto Chromosomes Involves Opening of Its SMC Hinge , 2006, Cell.

[93]  J. Ellenberg,et al.  Live-Cell Imaging Reveals a Stable Cohesin-Chromatin Interaction after but Not before DNA Replication , 2006, Current Biology.

[94]  Y. Toyoda,et al.  Coordinated requirements of human topo II and cohesin for metaphase centromere alignment under Mad2-dependent spindle checkpoint surveillance. , 2006, Molecular biology of the cell.

[95]  D. Dorsett,et al.  Effects of sister chromatid cohesion proteins on cut gene expression during wing development in Drosophila , 2005, Development.

[96]  H. Zou,et al.  Two human orthologues of Eco1/Ctf7 acetyltransferases are both required for proper sister-chromatid cohesion. , 2005, Molecular biology of the cell.

[97]  T. Hirano,et al.  Functional contribution of Pds5 to cohesin-mediated cohesion in human cells and Xenopus egg extracts , 2005, Journal of Cell Science.

[98]  E. Jabs,et al.  Roberts syndrome is caused by mutations in ESCO2, a human homolog of yeast ECO1 that is essential for the establishment of sister chromatid cohesion , 2005, Nature Genetics.

[99]  T. Hirano,et al.  Cohesin release is required for sister chromatid resolution, but not for condensin-mediated compaction, at the onset of mitosis. , 2002, Genes & development.

[100]  Mihoko Kai,et al.  Establishment and maintenance of sister chromatid cohesion in fission yeast by a unique mechanism , 2001, The EMBO journal.

[101]  K. Nasmyth,et al.  Sister chromatid cohesion is required for postreplicative double-strand break repair in Saccharomyces cerevisiae , 2001, Current Biology.

[102]  C. Rieder,et al.  Greatwall kinase , 2004, The Journal of cell biology.

[103]  A. Murray,et al.  Sister chromatid separation in frog egg extracts requires DNA topoisomerase II activity during anaphase , 1992, The Journal of cell biology.