Gait asymmetries in unilateral symptomatic hip osteoarthritis and their association with radiographic severity and pain

Introduction: Little is known about the loading patterns in unilateral hip osteoarthritis (OA) and their relationship to radiographic severity and pain. We aimed to examine the loading patterns at the hips of those with unilateral symptomatic hip OA and identify associations between radiographic severity and pain with loading alterations. Methods: 61 subjects with symptomatic unilateral hip OA underwent gait analyses and evaluation for radiographic severity (Kellgren-Lawrence [KL]-grade) and pain (visual analogue scale) at bilateral hips. Results: Hip OA subjects had greater range of motion and higher hip flexion, adduction, internal and external rotation moments at the contralateral, asymptomatic hip compared to the ipsilateral hip (p < 0.05). Correlations were noted between increasing KL-grade and increasing asymmetry of contralateral to ipsilateral hip loading (p < 0.05). There were no relationships with pain and loading asymmetry. Discussion: Unilateral symptomatic hip OA subjects demonstrate asymmetry in loading between the hips, with relatively greater loads at the contralateral hip. These loading asymmetries were directly related to the radiographic severity of symptomatic hip OA and not with pain. Conclusion: Additional research is needed to determine the role of gait asymmetries in disease progression.

[1]  T. P. Andriacchi,et al.  Gait Analysis as a Tool to Assess Joint Kinetics , 1985 .

[2]  James G Richards,et al.  A method for analyzing joint symmetry and normalcy, with an application to analyzing gait. , 2006, Gait & posture.

[3]  M. Dougados,et al.  Radiological progression of hip osteoarthritis: definition, risk factors and correlations with clinical status. , 1996, Annals of the rheumatic diseases.

[4]  J. Block,et al.  Relationship between pain and medial knee joint loading in mild radiographic knee osteoarthritis. , 2007, Arthritis and rheumatism.

[5]  Yuqing Zhang,et al.  Epidemiology of osteoarthritis. , 2013, Rheumatic diseases clinics of North America.

[6]  Najia Shakoor,et al.  Asymmetric loading and bone mineral density at the asymptomatic knees of patients with unilateral hip osteoarthritis. , 2011, Arthritis and rheumatism.

[7]  Najia Shakoor,et al.  Asymmetries and relationships between dynamic loading, muscle strength, and proprioceptive acuity at the knees in symptomatic unilateral hip osteoarthritis , 2014, Arthritis Research & Therapy.

[8]  H. Akiyama,et al.  Associations of radiographic degeneration and pain with daily cumulative hip loading in patients with secondary hip osteoarthritis , 2016, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[9]  Lars Nordsletten,et al.  Sagittal plane gait characteristics in hip osteoarthritis patients with mild to moderate symptoms compared to healthy controls: a cross-sectional study , 2012, BMC Musculoskeletal Disorders.

[10]  M. Maly Abnormal and cumulative loading in knee osteoarthritis. , 2008, Current opinion in rheumatology.

[11]  D. Hurwitz,et al.  Asymmetric knee loading in advanced unilateral hip osteoarthritis. , 2003, Arthritis and rheumatism.

[12]  P. Kutílek,et al.  Kinematic quantification of gait asymmetry in patients with peroneal nerve palsy based on bilateral cyclograms. , 2013, Journal of musculoskeletal & neuronal interactions.

[13]  C. Christiansen,et al.  Weight-bearing asymmetry in relation to measures of impairment and functional mobility for people with knee osteoarthritis. , 2010, Archives of physical medicine and rehabilitation.

[14]  K. An,et al.  Gait characteristics of patients with knee osteoarthritis. , 2001, Journal of biomechanics.

[15]  Laure Gossec,et al.  Gait analysis as a quantifiable outcome measure in hip or knee osteoarthritis: a systematic review. , 2010, Joint, bone, spine : revue du rhumatisme.

[16]  T. Andriacchi,et al.  Musculoskeletal dynamics, locomotion, and clinical applications , 1991 .

[17]  C. Helmick,et al.  Projections of US prevalence of arthritis and associated activity limitations. , 2006, Arthritis and rheumatism.

[18]  J Mizrahi,et al.  Some gait characteristics of below-knee amputees and their reflection on the ground reaction forces. , 1986, Engineering in medicine.

[19]  Najia Shakoor,et al.  Nonrandom evolution of end-stage osteoarthritis of the lower limbs. , 2002, Arthritis and rheumatism.

[20]  T. Andriacchi,et al.  Gait compensations in patients with osteoarthritis of the hip and their relationship to pain and passive hip motion , 1997, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[21]  I. Arostegui,et al.  Prevalence of knee and hip osteoarthritis and the appropriateness of joint replacement in an older population. , 2008, Archives of internal medicine.

[22]  C. Goldsmith,et al.  Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. , 1988, The Journal of rheumatology.

[23]  J. Kellgren,et al.  Radiological Assessment of Osteo-Arthrosis , 1957, Annals of the rheumatic diseases.

[24]  J. Sekiya,et al.  A clinically relevant review of hip biomechanics. , 2010, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[25]  T. Andriacchi Dynamics of pathological motion: applied to the anterior cruciate deficient knee. , 1990, Journal of biomechanics.

[26]  T. Andriacchi,et al.  The influence of total knee-replacement design on walking and stair-climbing. , 1982, The Journal of bone and joint surgery. American volume.

[27]  L. Nordsletten,et al.  Gait Characteristics, Symptoms, and Function in Persons With Hip Osteoarthritis: A Longitudinal Study With 6 to 7 Years of Follow-up. , 2015, The Journal of orthopaedic and sports physical therapy.

[28]  M. Wimmer,et al.  Contralateral hip and knee gait biomechanics are unchanged by total hip replacement for unilateral hip osteoarthritis. , 2012, Gait & posture.

[29]  Paul Ornetti,et al.  Three-dimensional kinematics of the lower limbs in hip osteoarthritis during walking. , 2011, Journal of back and musculoskeletal rehabilitation.

[30]  Jennifer M. Hootman,et al.  Prevalence of Doctor-Diagnosed Arthritis and Arthritis-Attributable Activity Limitation — United States, 2010–2012 , 2013, MMWR. Morbidity and mortality weekly report.

[31]  Bryan R. Schlink,et al.  Sagittal plane hip motion reversals during walking are associated with disease severity and poorer function in subjects with hip osteoarthritis. , 2012, Journal of biomechanics.

[32]  T D Cooke,et al.  The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hip. , 1991, Arthritis and rheumatism.

[33]  T. Andriacchi,et al.  A relationship between gait and clinical changes following high tibial osteotomy. , 1985, The Journal of bone and joint surgery. American volume.

[34]  S. Nho,et al.  Impact of Femoroacetabular Impingement Morphology on Gait Assessment in Symptomatic Patients , 2015, Sports health.

[35]  Debra E Hurwitz,et al.  Normalization of joint moments during gait: a comparison of two techniques. , 2003, Journal of biomechanics.